Senescence_CNS - Brain - Hippocampus (MMHCC)_GSE5078 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5078
Similar Terms
Downloads & Tools

Genes

600 genes differentially expressed during Senescence_CNS - Brain - Hippocampus (MMHCC)_GSE5078 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
CTSS cathepsin S 3.80834
SCN1B sodium channel, voltage gated, type I beta subunit 3.23686
GBAS glioblastoma amplified sequence 2.93521
C1QC complement component 1, q subcomponent, C chain 2.90448
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 2.87628
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 2.84402
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 2.83708
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 2.78141
SQSTM1 sequestosome 1 2.76208
ANKH ANKH inorganic pyrophosphate transport regulator 2.75499
SBF2 SET binding factor 2 2.75482
MECP2 methyl CpG binding protein 2 2.69876
NPC1 Niemann-Pick disease, type C1 2.66921
SGPL1 sphingosine-1-phosphate lyase 1 2.65097
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 2.64809
AHI1 Abelson helper integration site 1 2.62964
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.59833
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 2.57595
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.55671
TPD52L1 tumor protein D52-like 1 2.54717
S100A6 S100 calcium binding protein A6 2.53833
S100B S100 calcium binding protein B 2.51554
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 2.5074
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 2.47431
BIRC6 baculoviral IAP repeat containing 6 2.47191
PFDN2 prefoldin subunit 2 2.46463
CNN3 calponin 3, acidic 2.46408
TFCP2L1 transcription factor CP2-like 1 2.4213
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 2.42077
SREBF1 sterol regulatory element binding transcription factor 1 2.40684
DSTN destrin (actin depolymerizing factor) 2.40546
NPY neuropeptide Y 2.37958
PSAT1 phosphoserine aminotransferase 1 2.37911
LY86 lymphocyte antigen 86 2.36694
ADGRL2 adhesion G protein-coupled receptor L2 2.36468
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.35758
EID1 EP300 interacting inhibitor of differentiation 1 2.33991
WDR7 WD repeat domain 7 2.30962
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 2.30798
PAIP2B poly(A) binding protein interacting protein 2B 2.30691
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28 2.29953
ARGLU1 arginine and glutamate rich 1 2.29657
C1QB complement component 1, q subcomponent, B chain 2.29209
LPIN1 lipin 1 2.28404
RHOB ras homolog family member B 2.26463
SMAD1 SMAD family member 1 2.26025
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 2.25467
HLA-A major histocompatibility complex, class I, A 2.25302
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 2.24789
ARHGAP21 Rho GTPase activating protein 21 2.24184
GJA1 gap junction protein, alpha 1, 43kDa 2.23731
SCG5 secretogranin V 2.21998
PARL presenilin associated, rhomboid-like 2.2175
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.21491
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 2.18909
COPE coatomer protein complex, subunit epsilon 2.18325
PABPN1 poly(A) binding protein, nuclear 1 2.17201
SMNDC1 survival motor neuron domain containing 1 2.17063
C1QA complement component 1, q subcomponent, A chain 2.16998
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.15027
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.1415
ANXA5 annexin A5 2.14063
TSNAX translin-associated factor X 2.13762
HTRA1 HtrA serine peptidase 1 2.13643
DOCK9 dedicator of cytokinesis 9 2.13316
TEX30 testis expressed 30 2.11544
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.111
SYAP1 synapse associated protein 1 2.1019
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 2.09047
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 2.09018
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 2.08887
ANXA2 annexin A2 2.0636
CCDC94 coiled-coil domain containing 94 2.06244
TEX261 testis expressed 261 2.04465
ORC6 origin recognition complex, subunit 6 2.04378
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 2.02606
LRRC58 leucine rich repeat containing 58 2.02052
MAPK3 mitogen-activated protein kinase 3 2.01694
CADPS Ca++-dependent secretion activator 2.01036
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) 1.99932
ANGEL2 angel homolog 2 (Drosophila) 1.99886
ADIPOR2 adiponectin receptor 2 1.99615
CHD4 chromodomain helicase DNA binding protein 4 1.99615
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.99107
PDCD5 programmed cell death 5 1.96874
PGLYRP1 peptidoglycan recognition protein 1 1.95099
WNK2 WNK lysine deficient protein kinase 2 1.94829
IL17RA interleukin 17 receptor A 1.94556
RRAGC Ras-related GTP binding C 1.94518
TBCE tubulin folding cofactor E 1.94349
MYEOV2 myeloma overexpressed 2 1.92933
SDCBP syndecan binding protein (syntenin) 1.91147
RERE arginine-glutamic acid dipeptide (RE) repeats 1.89274
ETFB electron-transfer-flavoprotein, beta polypeptide 1.89081
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 1.89069
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 1.88979
RAD23B RAD23 homolog B (S. cerevisiae) 1.8837
USP48 ubiquitin specific peptidase 48 1.86279
MRPL16 mitochondrial ribosomal protein L16 1.85961
PELI1 pellino E3 ubiquitin protein ligase 1 1.8596
CELF4 CUGBP, Elav-like family member 4 1.85814
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.85044
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 1.84953
SUMO3 small ubiquitin-like modifier 3 1.84791
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.84764
TYROBP TYRO protein tyrosine kinase binding protein 1.8458
ILF3 interleukin enhancer binding factor 3, 90kDa 1.83463
TBK1 TANK-binding kinase 1 1.83381
GFAP glial fibrillary acidic protein 1.82955
SURF1 surfeit 1 1.82267
SRCAP Snf2-related CREBBP activator protein 1.81872
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 1.81785
CLIC4 chloride intracellular channel 4 1.81771
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.81627
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 1.81323
DCTN2 dynactin 2 (p50) 1.80467
COQ9 coenzyme Q9 1.80038
SRRT serrate, RNA effector molecule 1.79635
ACSL1 acyl-CoA synthetase long-chain family member 1 1.79428
PNO1 partner of NOB1 homolog (S. cerevisiae) 1.79231
SLC35E1 solute carrier family 35, member E1 1.79093
ECI2 enoyl-CoA delta isomerase 2 1.79085
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 1.78938
SELK selenoprotein K 1.78841
TMEM176A transmembrane protein 176A 1.78661
RPS26 ribosomal protein S26 1.77367
CENPI centromere protein I 1.7628
TRAPPC3 trafficking protein particle complex 3 1.76073
PDLIM1 PDZ and LIM domain 1 1.75831
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.75699
GTF2A2 general transcription factor IIA, 2, 12kDa 1.75684
CLDND1 claudin domain containing 1 1.75477
ELOVL5 ELOVL fatty acid elongase 5 1.7532
CDC42SE2 CDC42 small effector 2 1.74789
SWI5 SWI5 recombination repair homolog (yeast) 1.74722
TBRG1 transforming growth factor beta regulator 1 1.74013
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.73698
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.73086
CYHR1 cysteine/histidine-rich 1 1.72941
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 1.72133
DEGS1 delta(4)-desaturase, sphingolipid 1 1.72106
FHL1 four and a half LIM domains 1 1.72021
ROMO1 reactive oxygen species modulator 1 1.71223
WDR81 WD repeat domain 81 1.71203
PPAP2B phosphatidic acid phosphatase type 2B 1.71122
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.70937
SELPLG selectin P ligand 1.7066
VAMP4 vesicle-associated membrane protein 4 1.70586
C16ORF70 chromosome 16 open reading frame 70 1.69668
SRSF3 serine/arginine-rich splicing factor 3 1.69265
TMEM62 transmembrane protein 62 1.69213
RPL22 ribosomal protein L22 1.69158
TMEM176B transmembrane protein 176B 1.6914
TK2 thymidine kinase 2, mitochondrial 1.68401
MKL1 megakaryoblastic leukemia (translocation) 1 1.68313
GNAS GNAS complex locus 1.67819
ANLN anillin, actin binding protein 1.67794
RSL24D1 ribosomal L24 domain containing 1 1.67455
MPDU1 mannose-P-dolichol utilization defect 1 1.67432
RBM3 RNA binding motif (RNP1, RRM) protein 3 1.67172
B2M beta-2-microglobulin 1.67145
DOCK7 dedicator of cytokinesis 7 1.66066
PKP4 plakophilin 4 1.65972
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 1.65909
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 1.65468
FAM76B family with sequence similarity 76, member B 1.6491
TNRC6A trinucleotide repeat containing 6A 1.64682
NAGLU N-acetylglucosaminidase, alpha 1.64349
UXS1 UDP-glucuronate decarboxylase 1 1.63843
TMED7 transmembrane emp24 protein transport domain containing 7 1.63632
TFCP2 transcription factor CP2 1.63609
TPD52 tumor protein D52 1.63364
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.63171
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 1.6315
PCNA proliferating cell nuclear antigen 1.62344
ZFR2 zinc finger RNA binding protein 2 1.62334
CD47 CD47 molecule 1.62289
INPP5K inositol polyphosphate-5-phosphatase K 1.62199
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.62163
WNT10A wingless-type MMTV integration site family, member 10A 1.61796
SPARCL1 SPARC-like 1 (hevin) 1.61794
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.61381
RIN2 Ras and Rab interactor 2 1.61364
PVALB parvalbumin 1.60688
APOA1BP apolipoprotein A-I binding protein 1.60675
RREB1 ras responsive element binding protein 1 1.60614
RAB4A RAB4A, member RAS oncogene family 1.60601
NDRG1 N-myc downstream regulated 1 1.60202
HIAT1 hippocampus abundant transcript 1 1.60002
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 1.59684
RBBP4 retinoblastoma binding protein 4 1.59446
FAM32A family with sequence similarity 32, member A 1.59105
MERTK MER proto-oncogene, tyrosine kinase 1.59015
SCN1A sodium channel, voltage gated, type I alpha subunit 1.5886
PTGES3 prostaglandin E synthase 3 (cytosolic) 1.58472
MBNL1 muscleblind-like splicing regulator 1 1.58428
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.58239
PRPS1 phosphoribosyl pyrophosphate synthetase 1 1.57852
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.57764
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 1.57421
SDHAF1 succinate dehydrogenase complex assembly factor 1 1.57234
RAB8A RAB8A, member RAS oncogene family 1.57162
FERMT3 fermitin family member 3 1.56772
GNG5 guanine nucleotide binding protein (G protein), gamma 5 1.56744
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.56574
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 1.56405
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.56076
CARHSP1 calcium regulated heat stable protein 1, 24kDa 1.55894
TMC6 transmembrane channel-like 6 1.5552
SKAP2 src kinase associated phosphoprotein 2 1.5545
CPNE3 copine III 1.55444
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 1.55427
IGF1R insulin-like growth factor 1 receptor 1.55185
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.55147
UPP2 uridine phosphorylase 2 1.55042
CTSZ cathepsin Z 1.54982
RALBP1 ralA binding protein 1 1.54779
STXBP1 syntaxin binding protein 1 1.5451
CTAGE5 CTAGE family, member 5 1.54465
VRK3 vaccinia related kinase 3 1.54042
SMAD6 SMAD family member 6 1.53989
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 1.53965
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.53847
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 1.53773
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.53658
GOLGA4 golgin A4 1.53551
NKAIN1 Na+/K+ transporting ATPase interacting 1 1.53044
TNPO3 transportin 3 1.53034
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.52749
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.50796
MRPL48 mitochondrial ribosomal protein L48 1.50794
TTC33 tetratricopeptide repeat domain 33 1.50537
SEPHS2 selenophosphate synthetase 2 1.50515
LAPTM4A lysosomal protein transmembrane 4 alpha 1.50026
HDAC3 histone deacetylase 3 1.49864
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 1.49759
MYH9 myosin, heavy chain 9, non-muscle 1.49592
SKP1 S-phase kinase-associated protein 1 1.49154
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 1.49069
CSNK1A1 casein kinase 1, alpha 1 1.48229
ADGRL1 adhesion G protein-coupled receptor L1 1.48091
YTHDC1 YTH domain containing 1 1.47748
EIF5 eukaryotic translation initiation factor 5 1.4737
GCLC glutamate-cysteine ligase, catalytic subunit 1.47366
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.47097
RPS25 ribosomal protein S25 1.47032
LDLR low density lipoprotein receptor 1.46934
RNF208 ring finger protein 208 1.46715
FAM192A family with sequence similarity 192, member A 1.45618
ZNF639 zinc finger protein 639 1.45593
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.45341
ZRANB1 zinc finger, RAN-binding domain containing 1 1.44736
EGFL8 EGF-like-domain, multiple 8 1.4469
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.44535
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.44398
CANX calnexin 1.44113
TAOK3 TAO kinase 3 1.44111
RMI1 RecQ mediated genome instability 1 1.43998
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 1.43817
MAN1B1 mannosidase, alpha, class 1B, member 1 1.43729
EXOC7 exocyst complex component 7 1.43648
RAB11B RAB11B, member RAS oncogene family 1.43614
HARS histidyl-tRNA synthetase 1.43611
LGALS1 lectin, galactoside-binding, soluble, 1 1.43592
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.4316
CENPV centromere protein V 1.43104
GPX4 glutathione peroxidase 4 1.42954
ALOX15B arachidonate 15-lipoxygenase, type B 1.42802
SNAPIN SNAP-associated protein 1.42698
CST3 cystatin C 1.42696
ACTN4 actinin, alpha 4 1.42621
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 1.41476
SOD1 superoxide dismutase 1, soluble 1.4069
PITPNA phosphatidylinositol transfer protein, alpha 1.40501
THUMPD1 THUMP domain containing 1 1.40428
SCARB2 scavenger receptor class B, member 2 1.40371
C11ORF58 chromosome 11 open reading frame 58 1.40118
STX12 syntaxin 12 1.40046
SGK1 serum/glucocorticoid regulated kinase 1 1.39847
TFR2 transferrin receptor 2 1.39784
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 1.39415
EZR ezrin 1.3939
MVK mevalonate kinase 1.39228
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.39063
TBC1D15 TBC1 domain family, member 15 1.39004
ATRAID all-trans retinoic acid-induced differentiation factor 1.3898
METTL8 methyltransferase like 8 1.38835
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 1.38713
PNN pinin, desmosome associated protein 1.38674
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.38461
EIF4A2 eukaryotic translation initiation factor 4A2 1.38453
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 1.38347
CHMP5 charged multivesicular body protein 5 1.38338
RHOU ras homolog family member U 1.38188
ETF1 eukaryotic translation termination factor 1 1.37982
SRSF2 serine/arginine-rich splicing factor 2 1.37945
TUBB4A tubulin, beta 4A class IVa 1.37896
ITPKB inositol-trisphosphate 3-kinase B 1.37869
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.37452
MYO1D myosin ID 1.37101

decreased expression

Symbol Name Standardized Value
HDAC6 histone deacetylase 6 -3.57336
YBX1 Y box binding protein 1 -3.28846
BECN1 beclin 1, autophagy related -3.0762
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -3.02229
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -3.01267
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -2.96925
TUBG1 tubulin, gamma 1 -2.96659
DCTN3 dynactin 3 (p22) -2.92819
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -2.87469
FH fumarate hydratase -2.84809
IARS isoleucyl-tRNA synthetase -2.81039
DYNLL1 dynein, light chain, LC8-type 1 -2.7698
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.76684
ARF1 ADP-ribosylation factor 1 -2.73961
ATXN10 ataxin 10 -2.71272
CLTC clathrin, heavy chain (Hc) -2.709
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.62066
HTT huntingtin -2.59863
NTSR2 neurotensin receptor 2 -2.54993
PARP6 poly (ADP-ribose) polymerase family, member 6 -2.54543
RAP1GAP RAP1 GTPase activating protein -2.54014
LEMD2 LEM domain containing 2 -2.53729
HMGN1 high mobility group nucleosome binding domain 1 -2.51883
KIAA0100 KIAA0100 -2.50968
YIPF3 Yip1 domain family, member 3 -2.50611
LRP1 low density lipoprotein receptor-related protein 1 -2.50384
SAR1A secretion associated, Ras related GTPase 1A -2.49802
CS citrate synthase -2.49248
FAM98A family with sequence similarity 98, member A -2.46804
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -2.46491
LOC102288414 -2.45813
PTPRO protein tyrosine phosphatase, receptor type, O -2.45298
HSPA8 heat shock 70kDa protein 8 -2.45169
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -2.44233
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 -2.42958
WDR13 WD repeat domain 13 -2.42296
LARP1 La ribonucleoprotein domain family, member 1 -2.39573
PEX6 peroxisomal biogenesis factor 6 -2.38312
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.382
TMEM9B TMEM9 domain family, member B -2.3813
CCNDBP1 cyclin D-type binding-protein 1 -2.34746
FLII flightless I homolog (Drosophila) -2.34487
SKI SKI proto-oncogene -2.3181
LRRC59 leucine rich repeat containing 59 -2.31059
GTF2I general transcription factor IIi -2.30389
C18ORF32 chromosome 18 open reading frame 32 -2.29667
ADAM11 ADAM metallopeptidase domain 11 -2.29511
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 -2.28637
GLRX3 glutaredoxin 3 -2.27717
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -2.26789
NUP85 nucleoporin 85kDa -2.26255
TSC2 tuberous sclerosis 2 -2.25876
ACSS1 acyl-CoA synthetase short-chain family member 1 -2.25481
HOXD13 homeobox D13 -2.24679
PPA1 pyrophosphatase (inorganic) 1 -2.24522
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.23733
NPDC1 neural proliferation, differentiation and control, 1 -2.2254
SRPR signal recognition particle receptor (docking protein) -2.22153
HSPA4L heat shock 70kDa protein 4-like -2.22092
AGRN agrin -2.2201
MAEA macrophage erythroblast attacher -2.20891
MRPS14 mitochondrial ribosomal protein S14 -2.20013
C7ORF43 chromosome 7 open reading frame 43 -2.19301
PRUNE prune exopolyphosphatase -2.18963
FBL fibrillarin -2.17863
ATF4 activating transcription factor 4 -2.17861
IFT172 intraflagellar transport 172 -2.17116
SRP68 signal recognition particle 68kDa -2.16863
SPNS1 spinster homolog 1 (Drosophila) -2.16822
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -2.16462
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.16044
COMMD7 COMM domain containing 7 -2.15432
REEP5 receptor accessory protein 5 -2.15175
TIPRL TOR signaling pathway regulator -2.15107
KLC1 kinesin light chain 1 -2.13991
LDHA lactate dehydrogenase A -2.13958
ZNF444 zinc finger protein 444 -2.12573
LMO2 LIM domain only 2 (rhombotin-like 1) -2.12028
LDOC1L leucine zipper, down-regulated in cancer 1-like -2.11828
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -2.11669
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -2.11427
TP53BP1 tumor protein p53 binding protein 1 -2.1075
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.1003
DTX1 deltex 1, E3 ubiquitin ligase -2.0963
SIPA1L2 signal-induced proliferation-associated 1 like 2 -2.0943
SLC25A39 solute carrier family 25, member 39 -2.08885
GRWD1 glutamate-rich WD repeat containing 1 -2.08227
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -2.06791
MRPS31 mitochondrial ribosomal protein S31 -2.06501
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -2.06368
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -2.05961
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -2.05385
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -2.05379
RANGAP1 Ran GTPase activating protein 1 -2.05334
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -2.05306
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -2.04835
EDF1 endothelial differentiation-related factor 1 -2.04667
CORO1B coronin, actin binding protein, 1B -2.04577
CHGA chromogranin A -2.04243
COPS6 COP9 signalosome subunit 6 -2.04234
HDAC5 histone deacetylase 5 -2.04181
ADARB1 adenosine deaminase, RNA-specific, B1 -2.03671
ALAS1 5'-aminolevulinate synthase 1 -2.03311
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -2.02392
LENG9 leukocyte receptor cluster (LRC) member 9 -2.02224
ATP6AP1L ATPase, H+ transporting, lysosomal accessory protein 1-like -2.01995
NECAP1 NECAP endocytosis associated 1 -2.01616
TMEM208 transmembrane protein 208 -2.01483
MRPL52 mitochondrial ribosomal protein L52 -2.01207
INTS3 integrator complex subunit 3 -2.00459
BCAT1 branched chain amino-acid transaminase 1, cytosolic -2.00148
RHOT1 ras homolog family member T1 -2.00005
NXT1 nuclear transport factor 2-like export factor 1 -1.99227
MRPS36 mitochondrial ribosomal protein S36 -1.98771
ARL2BP ADP-ribosylation factor-like 2 binding protein -1.98669
CUL4A cullin 4A -1.98555
PRPF8 pre-mRNA processing factor 8 -1.98084
MYDGF myeloid-derived growth factor -1.97783
OSBPL5 oxysterol binding protein-like 5 -1.97565
TNPO2 transportin 2 -1.96922
DDAH2 dimethylarginine dimethylaminohydrolase 2 -1.96835
SEC31A SEC31 homolog A (S. cerevisiae) -1.96787
AP3B1 adaptor-related protein complex 3, beta 1 subunit -1.96546
SPOP speckle-type POZ protein -1.96457
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -1.96281
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.96125
GSTM3 glutathione S-transferase mu 3 (brain) -1.95915
FAM136A family with sequence similarity 136, member A -1.9587
MAP2K5 mitogen-activated protein kinase kinase 5 -1.95845
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -1.94159
SCG2 secretogranin II -1.93805
SPRED2 sprouty-related, EVH1 domain containing 2 -1.93737
ELOF1 elongation factor 1 homolog (S. cerevisiae) -1.93567
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -1.92858
BTBD17 BTB (POZ) domain containing 17 -1.92829
DMWD dystrophia myotonica, WD repeat containing -1.91706
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -1.91364
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -1.90776
MTMR10 myotubularin related protein 10 -1.90146
UNC50 unc-50 homolog (C. elegans) -1.89959
FAM20C family with sequence similarity 20, member C -1.8951
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 -1.89444
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -1.88876
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -1.88525
MMP17 matrix metallopeptidase 17 (membrane-inserted) -1.87728
DPF2 D4, zinc and double PHD fingers family 2 -1.86999
GAMT guanidinoacetate N-methyltransferase -1.86753
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 -1.85223
PGM1 phosphoglucomutase 1 -1.84894
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -1.84497
CACHD1 cache domain containing 1 -1.84381
C11ORF31 chromosome 11 open reading frame 31 -1.84356
PROM1 prominin 1 -1.84133
NGEF neuronal guanine nucleotide exchange factor -1.83886
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 -1.83668
GTPBP2 GTP binding protein 2 -1.83607
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -1.83204
TNKS1BP1 tankyrase 1 binding protein 1, 182kDa -1.83191
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -1.83099
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -1.82764
HSPH1 heat shock 105kDa/110kDa protein 1 -1.82513
TUBB3 tubulin, beta 3 class III -1.81926
RCOR2 REST corepressor 2 -1.81365
SIGMAR1 sigma non-opioid intracellular receptor 1 -1.81113
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.80975
FLCN folliculin -1.80914
ZNF706 zinc finger protein 706 -1.79529
LLGL1 lethal giant larvae homolog 1 (Drosophila) -1.79241
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -1.78868
TP53INP2 tumor protein p53 inducible nuclear protein 2 -1.78734
UROS uroporphyrinogen III synthase -1.78273
RGS14 regulator of G-protein signaling 14 -1.77992
PTGR1 prostaglandin reductase 1 -1.77926
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -1.77725
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -1.77461
DOC2B double C2-like domains, beta -1.77316
NAT8B N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) -1.76646
PIGM phosphatidylinositol glycan anchor biosynthesis, class M -1.76514
MRPL38 mitochondrial ribosomal protein L38 -1.75765
PABPC1 poly(A) binding protein, cytoplasmic 1 -1.75625
ATP13A2 ATPase type 13A2 -1.75496
DIAPH1 diaphanous-related formin 1 -1.75246
CACNB3 calcium channel, voltage-dependent, beta 3 subunit -1.74884
CALB1 calbindin 1, 28kDa -1.74737
ZFAND5 zinc finger, AN1-type domain 5 -1.73794
ICAM5 intercellular adhesion molecule 5, telencephalin -1.73667
ANKRD17 ankyrin repeat domain 17 -1.73543
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -1.73488
GGCT gamma-glutamylcyclotransferase -1.72164
CCT4 chaperonin containing TCP1, subunit 4 (delta) -1.72139
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -1.71944
EIF3D eukaryotic translation initiation factor 3, subunit D -1.71834
SRM spermidine synthase -1.71531
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -1.71423
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -1.71414
SIDT2 SID1 transmembrane family, member 2 -1.7109
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -1.70906
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -1.70906
PLK4 polo-like kinase 4 -1.70785
C20ORF24 chromosome 20 open reading frame 24 -1.70585
DEF8 differentially expressed in FDCP 8 homolog (mouse) -1.70351
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase -1.70275
BAG1 BCL2-associated athanogene -1.70148
UQCRHL ubiquinol-cytochrome c reductase hinge protein-like -1.70078
FAM50A family with sequence similarity 50, member A -1.69972
MOG myelin oligodendrocyte glycoprotein -1.69811
POU6F1 POU class 6 homeobox 1 -1.69653
NUP50 nucleoporin 50kDa -1.69568
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -1.69273
SOX4 SRY (sex determining region Y)-box 4 -1.68927
ADPRH ADP-ribosylarginine hydrolase -1.6876
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 -1.68622
MORF4L2 mortality factor 4 like 2 -1.68351
MARS methionyl-tRNA synthetase -1.68078
SIRT2 sirtuin 2 -1.67029
LEP leptin -1.67029
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -1.66842
NME1 NME/NM23 nucleoside diphosphate kinase 1 -1.66347
ESYT1 extended synaptotagmin-like protein 1 -1.65461
AGFG1 ArfGAP with FG repeats 1 -1.65193
DENND5A DENN/MADD domain containing 5A -1.63365
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.62684
MBD6 methyl-CpG binding domain protein 6 -1.62455
TMEM205 transmembrane protein 205 -1.62195
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -1.61842
CDK4 cyclin-dependent kinase 4 -1.6149
IL6ST interleukin 6 signal transducer -1.6118
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -1.60933
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 -1.6069
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -1.60575
HDHD2 haloacid dehalogenase-like hydrolase domain containing 2 -1.60228
ANKRD10 ankyrin repeat domain 10 -1.60177
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -1.60003
DLG3 discs, large homolog 3 (Drosophila) -1.59856
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -1.59782
MSH6 mutS homolog 6 -1.59651
NONO non-POU domain containing, octamer-binding -1.59358
FKBP1B FK506 binding protein 1B, 12.6 kDa -1.59354
CLDN11 claudin 11 -1.59336
TYSND1 trypsin domain containing 1 -1.59327
MTOR mechanistic target of rapamycin (serine/threonine kinase) -1.58989
MTCH2 mitochondrial carrier 2 -1.58123
JAGN1 jagunal homolog 1 (Drosophila) -1.57784
ACAD9 acyl-CoA dehydrogenase family, member 9 -1.57592
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -1.57349
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -1.57166
ARMCX2 armadillo repeat containing, X-linked 2 -1.57075
USP19 ubiquitin specific peptidase 19 -1.57026
INPP5B inositol polyphosphate-5-phosphatase, 75kDa -1.56972
GLO1 glyoxalase I -1.56871
GRAMD3 GRAM domain containing 3 -1.56845
AHCYL1 adenosylhomocysteinase-like 1 -1.56831
TESK1 testis-specific kinase 1 -1.56621
MFSD4 major facilitator superfamily domain containing 4 -1.56571
FNTA farnesyltransferase, CAAX box, alpha -1.56336
GSK3A glycogen synthase kinase 3 alpha -1.56065
SOCS5 suppressor of cytokine signaling 5 -1.55485
ZDHHC7 zinc finger, DHHC-type containing 7 -1.554
AATK apoptosis-associated tyrosine kinase -1.55132
AUP1 ancient ubiquitous protein 1 -1.55052
TRAF3 TNF receptor-associated factor 3 -1.54972
RBMX RNA binding motif protein, X-linked -1.54827
CCNG2 cyclin G2 -1.54525
TXN2 thioredoxin 2 -1.54422
BSDC1 BSD domain containing 1 -1.5384
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -1.53656
SLC16A6 solute carrier family 16, member 6 -1.53527
DCTN1 dynactin 1 -1.53477
DDA1 DET1 and DDB1 associated 1 -1.53458
TMTC2 transmembrane and tetratricopeptide repeat containing 2 -1.53438
BCKDK branched chain ketoacid dehydrogenase kinase -1.53409
TRAK2 trafficking protein, kinesin binding 2 -1.53115
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -1.52534
C8ORF37 chromosome 8 open reading frame 37 -1.52323
DOLPP1 dolichyldiphosphatase 1 -1.52162
NEO1 neogenin 1 -1.52085
EFHD2 EF-hand domain family, member D2 -1.5199
SCAMP3 secretory carrier membrane protein 3 -1.51865
RRM2 ribonucleotide reductase M2 -1.51829
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -1.51786
HAX1 HCLS1 associated protein X-1 -1.51609
RAB3IP RAB3A interacting protein -1.50746
RPF2 ribosome production factor 2 homolog (S. cerevisiae) -1.50724
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.50592
PPP1R15B protein phosphatase 1, regulatory subunit 15B -1.50553
PURB purine-rich element binding protein B -1.50493
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit -1.5042
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -1.5017
SQLE squalene epoxidase -1.50087
PTPRF protein tyrosine phosphatase, receptor type, F -1.49643
TSEN34 TSEN34 tRNA splicing endonuclease subunit -1.49346
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -1.49231
CXXC1 CXXC finger protein 1 -1.49121
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -1.48934
CDK18 cyclin-dependent kinase 18 -1.48663
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -1.48459
NUP62 nucleoporin 62kDa -1.48298
MARCKSL1 MARCKS-like 1 -1.47974
PPIB peptidylprolyl isomerase B (cyclophilin B) -1.4721
ACTL6B actin-like 6B -1.46841