Schizophrenia Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness. (Human Disease Ontology, DOID_5419)
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Genes

82 genes associated with the trait Schizophrenia in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
TRIM26 tripartite motif containing 26 1.0562
NKAPL NFKB activating protein-like 1.02473
TSPAN18 tetraspanin 18 1.01477
LSM1 LSM1, U6 small nuclear RNA associated 0.944178
NOTCH4 notch 4 0.922056
TCF4 transcription factor 4 0.807263
MPC2 mitochondrial pyruvate carrier 2 0.763999
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.731179
CSMD1 CUB and Sushi multiple domains 1 0.731179
NT5C2 5'-nucleotidase, cytosolic II 0.711358
SDCCAG8 serologically defined colon cancer antigen 8 0.685324
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.67572
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.64828
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.609816
ZNF804A zinc finger protein 804A 0.609816
RELN reelin 0.50886
CCDC60 coiled-coil domain containing 60 0.50084
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.50084
FAM69A family with sequence similarity 69, member A 0.497798
PLAA phospholipase A2-activating protein 0.443956
CALN1 calneuron 1 0.443956
PTPRG protein tyrosine phosphatase, receptor type, G 0.443956
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.443956
AGBL1 ATP/GTP binding protein-like 1 0.443956
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.435233
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.406869
RUNDC3B RUN domain containing 3B 0.406869
RERE arginine-glutamic acid dipeptide (RE) repeats 0.406869
PLCB2 phospholipase C, beta 2 0.406869
MSRA methionine sulfoxide reductase A 0.378873
RNLS renalase, FAD-dependent amine oxidase 0.366472
TRAF3 TNF receptor-associated factor 3 0.356676
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.356676
ERBB4 erb-b2 receptor tyrosine kinase 4 0.354498
TNIK TRAF2 and NCK interacting kinase 0.33862
SHISA9 shisa family member 9 0.33862
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.33862
RPL5 ribosomal protein L5 0.318735
CBX2 chromobox homolog 2 0.294905
KIAA0391 KIAA0391 0.280395
NALCN sodium leak channel, non selective 0.264819
PPP1R36 protein phosphatase 1, regulatory subunit 36 0.246291
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.242118
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.242118
OPCML opioid binding protein/cell adhesion molecule-like 0.226067
CDH13 cadherin 13 0.221103
SLC35A5 solute carrier family 35, member A5 0.202915
NRG1 neuregulin 1 0.199315
TC2N tandem C2 domains, nuclear 0.198924
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.182006
KMT2C lysine (K)-specific methyltransferase 2C 0.17671
ANKRD11 ankyrin repeat domain 11 0.173256
CAPN14 calpain 14 0.171576
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 0.167665
BTLA B and T lymphocyte associated 0.167029
PGPEP1 pyroglutamyl-peptidase I 0.161199
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.157131
SPTBN1 spectrin, beta, non-erythrocytic 1 0.153785
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 0.153511
KDM4C lysine (K)-specific demethylase 4C 0.149441
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 0.140513
ELP3 elongator acetyltransferase complex subunit 3 0.138406
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.131621
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 0.128991
KYNU kynureninase 0.128991
NREP neuronal regeneration related protein 0.128991
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 0.127124
HPGDS hematopoietic prostaglandin D synthase 0.126433
ARSG arylsulfatase G 0.125748
CERCAM cerebral endothelial cell adhesion molecule 0.125067
CCDC13 coiled-coil domain containing 13 0.111476
MACROD2 MACRO domain containing 2 0.104855
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.102995
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.092657
WWOX WW domain containing oxidoreductase 0.08923
ANO3 anoctamin 3 0.07985
NRCAM neuronal cell adhesion molecule 0.067999
PRMT7 protein arginine methyltransferase 7 0.067633
EMC2 ER membrane protein complex subunit 2 0.065921
CCSER1 coiled-coil serine-rich protein 1 0.063303
FHIT fragile histidine triad 0.059235
NINJ2 ninjurin 2 0.058196