Schizophrenia Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness. (Human Disease Ontology, DOID_5419)
External Link https://www.ebi.ac.uk/gwas/search?query=Schizophrenia
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Genes

66 genes associated with the Schizophrenia phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
TRIM26 tripartite motif containing 26 0.910257
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.725138
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.673878
TSPAN18 tetraspanin 18 0.656287
MIR137HG MIR137 host gene 0.637972
LSM1 LSM1, U6 small nuclear RNA associated 0.592545
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.592545
NOTCH4 notch 4 0.572839
TSNARE1 t-SNARE domain containing 1 0.572839
TCF4 transcription factor 4 0.560615
NT5C2 5'-nucleotidase, cytosolic II 0.499091
HHAT hedgehog acyltransferase 0.455873
QPCT glutaminyl-peptide cyclotransferase 0.449549
SLCO6A1 solute carrier organic anion transporter family, member 6A1 0.439318
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.434785
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like 0.434785
ZEB2 zinc finger E-box binding homeobox 2 0.434785
MPC2 mitochondrial pyruvate carrier 2 0.434785
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.405958
NGEF neuronal guanine nucleotide exchange factor 0.405958
CSMD1 CUB and Sushi multiple domains 1 0.405958
C12ORF65 chromosome 12 open reading frame 65 0.405958
SDCCAG8 serologically defined colon cancer antigen 8 0.389385
RENBP renin binding protein 0.377988
ZSWIM6 zinc finger, SWIM-type containing 6 0.377988
CTC-436P18.1 uncharacterized LOC101928630 0.377988
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.362242
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.351407
LOC101928882 uncharacterized LOC101928882 0.342586
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 0.342586
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.342586
BRD1 bromodomain containing 1 0.314454
ZNF804A zinc finger protein 804A 0.314454
VRK2 vaccinia related kinase 2 0.295129
POM121L2 POM121 transmembrane nucleoporin-like 2 0.280662
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.246511
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.246511
SNX29 sorting nexin 29 0.22914
RELN reelin 0.22914
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.220915
CCDC60 coiled-coil domain containing 60 0.220915
CDH13 cadherin 13 0.220915
PTPRG protein tyrosine phosphatase, receptor type, G 0.165905
CALN1 calneuron 1 0.165905
AGBL1 ATP/GTP binding protein-like 1 0.165905
PLAA phospholipase A2-activating protein 0.165905
CLC Charcot-Leyden crystal galectin 0.165905
PLCB2 phospholipase C, beta 2 0.129504
RERE arginine-glutamic acid dipeptide (RE) repeats 0.129504
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.129504
LINC01255 long intergenic non-protein coding RNA 1255 0.129504
MSRA methionine sulfoxide reductase A 0.104568
PRRC2A proline-rich coiled-coil 2A 0.104568
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.104568
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.104568
RORA RAR-related orphan receptor A 0.104568
ARHGAP31 Rho GTPase activating protein 31 0.085234
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.085234
FBXO11 F-box protein 11 0.070053
CNTNAP5 contactin associated protein-like 5 0.070053
SHISA9 shisa family member 9 0.070053
TENM3 teneurin transmembrane protein 3 0.070053
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.057619
KIF26B kinesin family member 26B 0.057619
NLRC5 NLR family, CARD domain containing 5 0.048624
ZFYVE28 zinc finger, FYVE domain containing 28 0.042592