Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Sarcoma_SARC (The Cancer Genome Atlas)
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Genes

458 genes with high or low expression in Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACTL7A actin-like 7A
ACTL7B actin-like 7B
ADGRE5 adhesion G protein-coupled receptor E5
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKIP1 A kinase (PRKA) interacting protein 1
ANKRD10 ankyrin repeat domain 10
ANKRD49 ankyrin repeat domain 49
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA13 annexin A13
ARHGAP1 Rho GTPase activating protein 1
ARL4D ADP-ribosylation factor-like 4D
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARL9 ADP-ribosylation factor-like 9
ASB16-AS1 ASB16 antisense RNA 1
ATL2 atlastin GTPase 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3
ATXN1 ataxin 1
AXIN1 axin 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GAT1 beta-1,3-glucuronyltransferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCAR4 breast cancer anti-estrogen resistance 4 (non-protein coding)
BCL9L B-cell CLL/lymphoma 9-like
BOLA1 bolA family member 1
BUD13 BUD13 homolog (S. cerevisiae)
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C11ORF84 chromosome 11 open reading frame 84
C15ORF32 chromosome 15 open reading frame 32
C16ORF58 chromosome 16 open reading frame 58
C16ORF62 chromosome 16 open reading frame 62
C16ORF91 chromosome 16 open reading frame 91
C1ORF220 chromosome 1 open reading frame 220
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C20ORF141 chromosome 20 open reading frame 141
C20ORF195 chromosome 20 open reading frame 195
C20ORF27 chromosome 20 open reading frame 27
C2ORF81 chromosome 2 open reading frame 81
C3ORF18 chromosome 3 open reading frame 18
C5 complement component 5
C9ORF3 chromosome 9 open reading frame 3
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CATSPER2P1 cation channel, sperm associated 2 pseudogene 1
CATSPERB catsper channel auxiliary subunit beta
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC15 coiled-coil domain containing 15
CCDC6 coiled-coil domain containing 6
CCDC71 coiled-coil domain containing 71
CCDC74A coiled-coil domain containing 74A
CCDC81 coiled-coil domain containing 81
CCDC82 coiled-coil domain containing 82
CCDC84 coiled-coil domain containing 84
CCDC87 coiled-coil domain containing 87
CCIN calicin
CCNA1 cyclin A1
CCNF cyclin F
CCNY cyclin Y
CD24 CD24 molecule
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK1 cyclin-dependent kinase 1
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDR2 cerebellar degeneration-related protein 2, 62kDa
CENPK centromere protein K
CEP164 centrosomal protein 164kDa
CHEK1 checkpoint kinase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CISD1 CDGSH iron sulfur domain 1
CKAP2 cytoskeleton associated protein 2
CLDN23 claudin 23
CLUAP1 clusterin associated protein 1
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNGA4 cyclic nucleotide gated channel alpha 4
CNIH2 cornichon family AMPA receptor auxiliary protein 2
CNKSR3 CNKSR family member 3
COG7 component of oligomeric golgi complex 7
COLCA2 colorectal cancer associated 2
CREB3L4 cAMP responsive element binding protein 3-like 4
CRMP1 collapsin response mediator protein 1
CTBS chitobiase, di-N-acetyl-
CTNNBL1 catenin, beta like 1
CTU1 cytosolic thiouridylase subunit 1
CWC22 CWC22 spliceosome-associated protein
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DCST2 DC-STAMP domain containing 2
DCTN5 dynactin 5 (p25)
DCX doublecortin
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
DFNB59 deafness, autosomal recessive 59
DGUOK deoxyguanosine kinase
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DIRC3 disrupted in renal carcinoma 3
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPYSL4 dihydropyrimidinase-like 4
E4F1 E4F transcription factor 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFCAB1 EF-hand calcium binding domain 1
EHD1 EH-domain containing 1
EI24 etoposide induced 2.4
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHB4 EPH receptor B4
EPO erythropoietin
ERI2 ERI1 exoribonuclease family member 2
ESYT3 extended synaptotagmin-like protein 3
ETAA1 Ewing tumor-associated antigen 1
FAM117A family with sequence similarity 117, member A
FAM124A family with sequence similarity 124A
FAM131B family with sequence similarity 131, member B
FAM174B family with sequence similarity 174, member B
FAM189B family with sequence similarity 189, member B
FAM209A family with sequence similarity 209, member A
FAM72B family with sequence similarity 72, member B
FAM72D family with sequence similarity 72, member D
FAM83H family with sequence similarity 83, member H
FAM86C1 family with sequence similarity 86, member C1
FAM89B family with sequence similarity 89, member B
FAR1 fatty acyl CoA reductase 1
FAR2 fatty acyl CoA reductase 2
FBRS fibrosin
FBXL19 F-box and leucine-rich repeat protein 19
FDXACB1 ferredoxin-fold anticodon binding domain containing 1
FILIP1L filamin A interacting protein 1-like
FLYWCH1 FLYWCH-type zinc finger 1
FOXH1 forkhead box H1
FOXL2NB FOXL2 neighbor
FOXO1 forkhead box O1
FOXRED1 FAD-dependent oxidoreductase domain containing 1
GAB2 GRB2-associated binding protein 2
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIP gastric inhibitory polypeptide
GLB1L2 galactosidase, beta 1-like 2
GLB1L3 galactosidase, beta 1-like 3
GLIPR2 GLI pathogenesis-related 2
GLIS1 GLIS family zinc finger 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GPR161 G protein-coupled receptor 161
GPR21 G protein-coupled receptor 21
GPR35 G protein-coupled receptor 35
GRTP1 growth hormone regulated TBC protein 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H2C GTF2H2 family member C
GYLTL1B glycosyltransferase-like 1B
H2AFX H2A histone family, member X
HARBI1 harbinger transposase derived 1
HAUS1 HAUS augmin-like complex, subunit 1
HDDC2 HD domain containing 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HGFAC HGF activator
HINFP histone H4 transcription factor
HIRIP3 HIRA interacting protein 3
HMBS hydroxymethylbilane synthase
HOPX HOP homeobox
HOXD10 homeobox D10
HOXD11 homeobox D11
HOXD9 homeobox D9
HPCAL1 hippocalcin-like 1
HS1BP3 HCLS1 binding protein 3
HULC hepatocellular carcinoma up-regulated long non-coding RNA
HYLS1 hydrolethalus syndrome 1
IFT46 intraflagellar transport 46
IFT88 intraflagellar transport 88
INO80E INO80 complex subunit E
INTS3 integrator complex subunit 3
IQCF5 IQ motif containing F5
ITFG3 integrin alpha FG-GAP repeat containing 3
JADE3 jade family PHD finger 3
JMJD4 jumonji domain containing 4
JMJD8 jumonji domain containing 8
JRKL JRK-like
KATNBL1 katanin p80 subunit B-like 1
KCTD5 potassium channel tetramerization domain containing 5
KIAA0226L KIAA0226-like
KIF14 kinesin family member 14
KIF2A kinesin heavy chain member 2A
KIN Kin17 DNA and RNA binding protein
KLHDC8B kelch domain containing 8B
KLHDC9 kelch domain containing 9
KLHL25 kelch-like family member 25
KLHL4 kelch-like family member 4
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KNOP1 lysine-rich nucleolar protein 1
KRBA1 KRAB-A domain containing 1
KRT9 keratin 9, type I
L3HYPDH L-3-hydroxyproline dehydratase (trans-)
LBH limb bud and heart development
LEFTY2 left-right determination factor 2
LGI2 leucine-rich repeat LGI family, member 2
LIG3 ligase III, DNA, ATP-dependent
LMNA lamin A/C
LOC100133985 uncharacterized LOC100133985
LOC150776 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) pseudogene
LOC388242 coiled-coil domain containing 101 pseudogene
LOC494141 solute carrier family 25, member 51 pseudogene
LOC613037 nuclear pore complex interacting protein pseudogene
LOC727896 cysteine and histidine-rich domain (CHORD) containing 1 pseudogene
LOC81691 exonuclease NEF-sp
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP12 low density lipoprotein receptor-related protein 12
LRRC46 leucine rich repeat containing 46
LRRC55 leucine rich repeat containing 55
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MCU mitochondrial calcium uniporter
MEAF6 MYST/Esa1-associated factor 6
MED17 mediator complex subunit 17
MESDC1 mesoderm development candidate 1
MESTIT1 MEST intronic transcript 1, antisense RNA
METRN meteorin, glial cell differentiation regulator
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MIMT1 MER1 repeat containing imprinted transcript 1 (non-protein coding)
MINA MYC induced nuclear antigen
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP10 matrix metallopeptidase 10
MMP28 matrix metallopeptidase 28
MORN5 MORN repeat containing 5
MOSPD3 motile sperm domain containing 3
MPRIP myosin phosphatase Rho interacting protein
MROH6 maestro heat-like repeat family member 6
MRPS31 mitochondrial ribosomal protein S31
MRPS6 mitochondrial ribosomal protein S6
MSH5 mutS homolog 5
MSRB2 methionine sulfoxide reductase B2
MUS81 MUS81 structure-specific endonuclease subunit
MYCBPAP MYCBP associated protein
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NAT14 N-acetyltransferase 14 (GCN5-related, putative)
NEK3 NIMA-related kinase 3
NLN neurolysin (metallopeptidase M3 family)
NLRX1 NLR family member X1
NMRAL1 NmrA-like family domain containing 1
NPEPL1 aminopeptidase-like 1
NPR1 natriuretic peptide receptor 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NSRP1 nuclear speckle splicing regulatory protein 1
NSUN5 NOP2/Sun domain family, member 5
NTN1 netrin 1
NUBP2 nucleotide binding protein 2
NUF2 NUF2, NDC80 kinetochore complex component
OR2B2 olfactory receptor, family 2, subfamily B, member 2
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene)
OR51E2 olfactory receptor, family 51, subfamily E, member 2
ORC3 origin recognition complex, subunit 3
OSBPL5 oxysterol binding protein-like 5
PAGR1 PAXIP1 associated glutamate-rich protein 1
PAQR4 progestin and adipoQ receptor family member IV
PARN poly(A)-specific ribonuclease
PARVA parvin, alpha
PATE4 prostate and testis expressed 4
PCBP1 poly(rC) binding protein 1
PCSK4 proprotein convertase subtilisin/kexin type 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD7 programmed cell death 7
PDZD7 PDZ domain containing 7
PEG3 paternally expressed 3
PFKP phosphofructokinase, platelet
PFN4 profilin family, member 4
PGAP2 post-GPI attachment to proteins 2
PGM2 phosphoglucomutase 2
PGM2L1 phosphoglucomutase 2-like 1
PHF19 PHD finger protein 19
PIH1D2 PIH1 domain containing 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLAC1 placenta-specific 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK1 polo-like kinase 1
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2P1 postmeiotic segregation increased 2 pseudogene 1
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R12C protein phosphatase 1, regulatory subunit 12C
PRH1 proline-rich protein HaeIII subfamily 1
PRKCDBP protein kinase C, delta binding protein
PRPF3 pre-mRNA processing factor 3
PRR14 proline rich 14
PRSS27 protease, serine 27
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTS 6-pyruvoyltetrahydropterin synthase
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RAB23 RAB23, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAD51D RAD51 paralog D
RAP1A RAP1A, member of RAS oncogene family
RASIP1 Ras interacting protein 1
RBM24 RNA binding motif protein 24
RBM44 RNA binding motif protein 44
RELL1 RELT-like 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
REXO2 RNA exonuclease 2
RFC3 replication factor C (activator 1) 3, 38kDa
RFTN1 raftlin, lipid raft linker 1
RGPD8 RANBP2-like and GRIP domain containing 8
RGS2 regulator of G-protein signaling 2
RMI2 RecQ mediated genome instability 2
RNF115 ring finger protein 115
RNF151 ring finger protein 151
RNF214 ring finger protein 214
RNF26 ring finger protein 26
RNPEP arginyl aminopeptidase (aminopeptidase B)
RNPS1 RNA binding protein S1, serine-rich domain
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS10P7 ribosomal protein S10 pseudogene 7
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUVBL1 RuvB-like AAA ATPase 1
S100A7 S100 calcium binding protein A7
S100PBP S100P binding protein
SAMD1 sterile alpha motif domain containing 1
SAPCD1 suppressor APC domain containing 1
SARM1 sterile alpha and TIR motif containing 1
SDCBP2 syndecan binding protein (syntenin) 2
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans)
SEMG1 semenogelin I
SF3A2 splicing factor 3a, subunit 2, 66kDa
SF3B4 splicing factor 3b, subunit 4, 49kDa
SFT2D2 SFT2 domain containing 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35F3 solute carrier family 35, member F3
SLX4 SLX4 structure-specific endonuclease subunit
SNAP23 synaptosomal-associated protein, 23kDa
SNORA37 small nucleolar RNA, H/ACA box 37
SNX19 sorting nexin 19
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPDYA speedy/RINGO cell cycle regulator family member A
SPDYE3 speedy/RINGO cell cycle regulator family member E3
SREK1IP1 SREK1-interacting protein 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST5 suppression of tumorigenicity 5
STAC SH3 and cysteine rich domain
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STKLD1 serine/threonine kinase-like domain containing 1
STX1B syntaxin 1B
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TADA3 transcriptional adaptor 3
TAGLN transgelin
TAS2R50 taste receptor, type 2, member 50
TAS2R60 taste receptor, type 2, member 60
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D10B TBC1 domain family, member 10B
TBX6 T-box 6
TC2N tandem C2 domains, nuclear
TDRD1 tudor domain containing 1
TEAD2 TEA domain family member 2
TEAD3 TEA domain family member 3
TEX12 testis expressed 12
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFDP3 transcription factor Dp family, member 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THUMPD1 THUMP domain containing 1
TIPRL TOR signaling pathway regulator
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TKFC triokinase/FMN cyclase
TMEM132D transmembrane protein 132D
TMEM138 transmembrane protein 138
TMEM14A transmembrane protein 14A
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM200B transmembrane protein 200B
TMEM79 transmembrane protein 79
TMEM80 transmembrane protein 80
TMEM8A transmembrane protein 8A
TMSB15B thymosin beta 15B
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TNFAIP8L3 tumor necrosis factor, alpha-induced protein 8-like 3
TP53 tumor protein p53
TPD52L1 tumor protein D52-like 1
TPM4 tropomyosin 4
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIM45 tripartite motif containing 45
TRIM9 tripartite motif containing 9
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TROVE2 TROVE domain family, member 2
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TSC22D1 TSC22 domain family, member 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSIX TSIX transcript, XIST antisense RNA
TSPAN15 tetraspanin 15
TSPAN18 tetraspanin 18
TSPAN2 tetraspanin 2
TSSC4 tumor suppressing subtransferable candidate 4
TTBK1 tau tubulin kinase 1
TTC9C tetratricopeptide repeat domain 9C
TULP2 tubby like protein 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBA3 ubiquitin-like modifier activating enzyme 3
UBALD1 UBA-like domain containing 1
UBE2I ubiquitin-conjugating enzyme E2I
UBE2T ubiquitin-conjugating enzyme E2T
UBE4A ubiquitination factor E4A
UBFD1 ubiquitin family domain containing 1
UBQLN4 ubiquilin 4
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UFSP1 UFM1-specific peptidase 1 (non-functional)
USP2 ubiquitin specific peptidase 2
USP31 ubiquitin specific peptidase 31
USP35 ubiquitin specific peptidase 35
USP6 ubiquitin specific peptidase 6
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
UTS2B urotensin 2B
VAV3 vav 3 guanine nucleotide exchange factor
VMAC vimentin-type intermediate filament associated coiled-coil protein
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
VRK2 vaccinia related kinase 2
VSTM2L V-set and transmembrane domain containing 2 like
VSTM5 V-set and transmembrane domain containing 5
VWA7 von Willebrand factor A domain containing 7
WBSCR17 Williams-Beuren syndrome chromosome region 17
WBSCR27 Williams Beuren syndrome chromosome region 27
WDR24 WD repeat domain 24
WDR77 WD repeat domain 77
WT1 Wilms tumor 1
XKR6 XK, Kell blood group complex subunit-related family, member 6
XPO6 exportin 6
ZBTB3 zinc finger and BTB domain containing 3
ZBTB45 zinc finger and BTB domain containing 45
ZC3H3 zinc finger CCCH-type containing 3
ZNF189 zinc finger protein 189
ZNF213 zinc finger protein 213
ZNF22 zinc finger protein 22
ZNF232 zinc finger protein 232
ZNF239 zinc finger protein 239
ZNF263 zinc finger protein 263
ZNF34 zinc finger protein 34
ZNF48 zinc finger protein 48
ZNF517 zinc finger protein 517
ZNF598 zinc finger protein 598
ZNF688 zinc finger protein 688
ZNF747 zinc finger protein 747
ZNF764 zinc finger protein 764
ZNF775 zinc finger protein 775
ZNF785 zinc finger protein 785
ZNF830 zinc finger protein 830
ZNF837 zinc finger protein 837
ZYX zyxin

low expression

Symbol Name
FAM127B family with sequence similarity 127, member B
FAM127C family with sequence similarity 127, member C
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
SCLY selenocysteine lyase
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
ZNF449 zinc finger protein 449
ZNF75D zinc finger protein 75D