Sarcoma, Ewing Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cancer (Genetic Association Database)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D012512
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Genes

105 genes/proteins associated with the disease Sarcoma, Ewing from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CIZ1 CDKN1A interacting zinc finger protein 1 2.88009
EWSR1 EWS RNA-binding protein 1 2.88009
FLI1 Fli-1 proto-oncogene, ETS transcription factor 2.88009
GSTP1 glutathione S-transferase pi 1 1.68612
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.57641
CDK2 cyclin-dependent kinase 2 1.51004
BAX BCL2-associated X protein 1.50248
PARP1 poly (ADP-ribose) polymerase 1 1.49584
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.46304
BCL2 B-cell CLL/lymphoma 2 1.46093
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.40925
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.4065
TP53 tumor protein p53 1.40316
VEGFA vascular endothelial growth factor A 1.39114
RBM17 RNA binding motif protein 17 1.38242
FHL1 four and a half LIM domains 1 1.36648
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.35618
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.35386
BCL2A1 BCL2-related protein A1 1.32339
IL6 interleukin 6 1.30087
H2AFX H2A histone family, member X 1.28827
TOP2A topoisomerase (DNA) II alpha 170kDa 1.28827
MCL1 myeloid cell leukemia 1 1.27533
TNF tumor necrosis factor 1.26298
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.26205
EMP3 epithelial membrane protein 3 1.2509
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.24275
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.2208
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.21337
HMGA2 high mobility group AT-hook 2 1.21337
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.21173
CHEK2 checkpoint kinase 2 1.21108
GPX3 glutathione peroxidase 3 1.21108
BCL2L1 BCL2-like 1 1.21108
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.21076
BAK1 BCL2-antagonist/killer 1 1.20848
IL23A interleukin 23, alpha subunit p19 1.20784
MAPK3 mitogen-activated protein kinase 3 1.19312
SP1 Sp1 transcription factor 1.19213
BTG2 BTG family, member 2 1.19179
MAPK1 mitogen-activated protein kinase 1 1.18521
TYMP thymidine phosphorylase 1.17431
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.17399
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.17034
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.16866
PLAU plasminogen activator, urokinase 1.16799
FASLG Fas ligand (TNF superfamily, member 6) 1.16533
TYMS thymidylate synthetase 1.16302
GSTM1 glutathione S-transferase mu 1 1.15695
CYCS cytochrome c, somatic 1.15627
CAT catalase 1.1556
BIRC3 baculoviral IAP repeat containing 3 1.15357
EGR1 early growth response 1 1.14404
FAS Fas cell surface death receptor 1.14268
RGL1 ral guanine nucleotide dissociation stimulator-like 1 1.13793
STK17A serine/threonine kinase 17a 1.12838
STAT1 signal transducer and activator of transcription 1, 91kDa 1.12634
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.12495
SOD2 superoxide dismutase 2, mitochondrial 1.12461
HRAS Harvey rat sarcoma viral oncogene homolog 1.12014
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.11536
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.1122
CDK4 cyclin-dependent kinase 4 1.10424
ATG7 autophagy related 7 1.09822
BID BH3 interacting domain death agonist 1.09083
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.08726
CCNA2 cyclin A2 1.08655
FOS FBJ murine osteosarcoma viral oncogene homolog 1.08161
TXNRD1 thioredoxin reductase 1 1.08019
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.06844
RUNX3 runt-related transcription factor 3 1.06808
CDC25C cell division cycle 25C 1.06661
BBC3 BCL2 binding component 3 1.06044
DUSP2 dual specificity phosphatase 2 1.05828
KAT2B K(lysine) acetyltransferase 2B 1.05423
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.052
BIRC2 baculoviral IAP repeat containing 2 1.05163
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.04868
CFLAR CASP8 and FADD-like apoptosis regulator 1.04831
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.04684
TXNIP thioredoxin interacting protein 1.04574
EDNRB endothelin receptor type B 1.03864
BCL2L2 BCL2-like 2 1.03864
BRCA1 breast cancer 1, early onset 1.03715
BIRC5 baculoviral IAP repeat containing 5 1.03456
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.03419
TUBA4A tubulin, alpha 4a 1.03308
SGK1 serum/glucocorticoid regulated kinase 1 1.02896
GADD45A growth arrest and DNA-damage-inducible, alpha 1.02746
RBBP4 retinoblastoma binding protein 4 1.02634
MT1G metallothionein 1G 1.02634
F3 coagulation factor III (thromboplastin, tissue factor) 1.02634
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.02522
PROCR protein C receptor, endothelial 1.0241
ERBB2 erb-b2 receptor tyrosine kinase 2 1.02373
MGMT O-6-methylguanine-DNA methyltransferase 1.02003
CHEK1 checkpoint kinase 1 1.02003
BAG1 BCL2-associated athanogene 1.01814
TGFB1 transforming growth factor, beta 1 1.01663
NOS2 nitric oxide synthase 2, inducible 1.01625
ATM ATM serine/threonine kinase 1.01625
CCNB1 cyclin B1 1.01474
ATR ATR serine/threonine kinase 1.01286
CD44 CD44 molecule (Indian blood group) 1.01212
VCAM1 vascular cell adhesion molecule 1 1.01174