SUP-M2 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Human anaplastic large cell lymphoma (ALCL) cell line; derived from the cerebrospinal fluid of a 5-year-old girl with refractory malignant histiocytosis. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004775)
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Genes

179 genes with high or low copy number in SUP-M2 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
G0S2 G0/G1 switch 2 3.12177
RBBP5 retinoblastoma binding protein 5 3.12177
PM20D1 peptidase M20 domain containing 1 3.12177
PLXNA2 plexin A2 3.12177
USH2A Usher syndrome 2A (autosomal recessive, mild) 3.12177
KCTD3 potassium channel tetramerization domain containing 3 3.12177
TRAF3IP3 TRAF3 interacting protein 3 3.12177
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 3.12177
TMEM81 transmembrane protein 81 3.12177
ASCL5 achaete-scute family bHLH transcription factor 5 3.12177
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 3.12177
IRF6 interferon regulatory factor 6 3.12177
MIR205HG MIR205 host gene 3.12177
LAD1 ladinin 1 3.12177
SMYD2 SET and MYND domain containing 2 3.12177
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 3.12177
ANGEL2 angel homolog 2 (Drosophila) 3.12177
IPO9 importin 9 3.12177
SERTAD4 SERTA domain containing 4 3.12177
MYBPH myosin binding protein H 3.12177
LOC148696 uncharacterized LOC148696 3.12177
DIEXF digestive organ expansion factor homolog (zebrafish) 3.12177
CD34 CD34 molecule 3.12177
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 3.12177
CDK18 cyclin-dependent kinase 18 3.12177
LOC284578 uncharacterized LOC284578 3.12177
MIR205 microRNA 205 3.12177
TNNI1 troponin I type 1 (skeletal, slow) 3.12177
PKP1 plakophilin 1 3.12177
TNNT2 troponin T type 2 (cardiac) 3.12177
DSTYK dual serine/threonine and tyrosine protein kinase 3.12177
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 3.12177
LOC148709 actin pseudogene 3.12177
SLC26A9 solute carrier family 26 (anion exchanger), member 9 3.12177
NUAK2 NUAK family, SNF1-like kinase, 2 3.12177
CSRP1 cysteine and glycine-rich protein 1 3.12177
SERTAD4-AS1 SERTAD4 antisense RNA 1 3.12177
VASH2 vasohibin 2 3.12177
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 3.12177
FAM72A family with sequence similarity 72, member A 3.12177
LEMD1 LEM domain containing 1 3.12177
CAMK1G calcium/calmodulin-dependent protein kinase IG 3.12177
CNTN2 contactin 2 (axonal) 3.12177
CYB5R1 cytochrome b5 reductase 1 3.12177
LINC00538 long intergenic non-protein coding RNA 538 3.12177
LEMD1-AS1 LEMD1 antisense RNA 1 3.12177
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 3.12177
ADIPOR1 adiponectin receptor 1 3.12177
MIR135B microRNA 135b 3.12177
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 3.12177
MFSD4 major facilitator superfamily domain containing 4 3.12177
KLHDC8A kelch domain containing 8A 3.12177
SYT14 synaptotagmin XIV 3.12177
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 3.12177
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 3.12177
TATDN3 TatD DNase domain containing 3 3.12177
KLHL12 kelch-like family member 12 3.12177
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 3.12177
GPATCH2 G patch domain containing 2 3.12177
C1ORF74 chromosome 1 open reading frame 74 3.12177
LOC284581 uncharacterized LOC284581 3.12177
BATF3 basic leucine zipper transcription factor, ATF-like 3 3.12177
PROX1 prospero homeobox 1 3.12177
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 3.12177
LAMB3 laminin, beta 3 3.12177
SPATA17 spermatogenesis associated 17 3.12177
MIR4260 microRNA 4260 3.12177
MYOG myogenin (myogenic factor 4) 3.12177
TMEM183A transmembrane protein 183A 3.12177
RABIF RAB interacting factor 3.12177
LINC00210 long intergenic non-protein coding RNA 210 3.12177
ADORA1 adenosine A1 receptor 3.12177
KIF21B kinesin family member 21B 3.12177
NSL1 NSL1, MIS12 kinetochore complex component 3.12177
KCNK2 potassium channel, two pore domain subfamily K, member 2 3.12177
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.12177
HHAT hedgehog acyltransferase 3.12177
RNPEP arginyl aminopeptidase (aminopeptidase B) 3.12177
SLC45A3 solute carrier family 45, member 3 3.12177
TMEM9 transmembrane protein 9 3.12177
TMCC2 transmembrane and coiled-coil domain family 2 3.12177
RPS10P7 ribosomal protein S10 pseudogene 7 3.12177
FLVCR1-AS1 FLVCR1 antisense RNA 1 (head to head) 3.12177
LMOD1 leiomodin 1 (smooth muscle) 3.12177
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 3.12177
SHISA4 shisa family member 4 3.12177
FAM71A family with sequence similarity 71, member A 2.93899
AVPR1B arginine vasopressin receptor 1B 2.93899
CD46 CD46 molecule, complement regulatory protein 2.93899
YOD1 YOD1 deubiquitinase 2.93899
C1ORF116 chromosome 1 open reading frame 116 2.93899
RCOR3 REST corepressor 3 2.93899
PIGR polymeric immunoglobulin receptor 2.93899
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2.93899
ARL8A ADP-ribosylation factor-like 8A 2.93899
FCAMR Fc receptor, IgA, IgM, high affinity 2.93899
EIF2D eukaryotic translation initiation factor 2D 2.93899
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 2.93899
GPR37L1 G protein-coupled receptor 37 like 1 2.93899
ESRRG estrogen-related receptor gamma 2.93899
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.93899
FCMR Fc fragment of IgM receptor 2.93899
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.93899
BTG2 BTG family, member 2 2.93899
TMEM206 transmembrane protein 206 2.93899
NEK2 NIMA-related kinase 2 2.93899
IL24 interleukin 24 2.93899
C4BPA complement component 4 binding protein, alpha 2.93899
C4BPB complement component 4 binding protein, beta 2.93899
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.93899
PPP1R12B protein phosphatase 1, regulatory subunit 12B 2.93899
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C 2.93899
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.93899
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.93899
CR1L complement component (3b/4b) receptor 1-like 2.93899
IL10 interleukin 10 2.93899
SYT2 synaptotagmin II 2.93899
C1ORF186 chromosome 1 open reading frame 186 2.93899
IL20 interleukin 20 2.93899
C1ORF106 chromosome 1 open reading frame 106 2.93899
CTSE cathepsin E 2.93899
CHIT1 chitinase 1 (chitotriosidase) 2.93899
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.93899
MIR29C microRNA 29c 2.93899
IL19 interleukin 19 2.93899
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2.93899
CENPF centromere protein F, 350/400kDa 2.93899
KDM5B lysine (K)-specific demethylase 5B 2.93899
CR2 complement component (3d/Epstein Barr virus) receptor 2 2.93899
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 2.93899
NENF neudesin neurotrophic factor 2.93899
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.93899
SNORA16B small nucleolar RNA, H/ACA box 16B 2.93899
ATF3 activating transcription factor 3 2.93899
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 2.93899
MIR3122 microRNA 3122 2.93899
UBE2T ubiquitin-conjugating enzyme E2T 2.93899
INTS7 integrator complex subunit 7 2.93899
FMOD fibromodulin 2.76305
REN renin 2.76305
LRRN2 leucine rich repeat neuronal 2 2.76305
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 2.76305
MDM4 MDM4, p53 regulator 2.76305
KISS1 KiSS-1 metastasis-suppressor 2.76305
NFASC neurofascin 2.76305
LINC00628 long intergenic non-protein coding RNA 628 2.76305
ETNK2 ethanolamine kinase 2 2.76305
PPP1R15B protein phosphatase 1, regulatory subunit 15B 2.76305
PTPRVP protein tyrosine phosphatase, receptor type, V, pseudogene 2.76305
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 2.76305
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.76305
GOLT1A golgi transport 1A 2.76305
PLEKHA6 pleckstrin homology domain containing, family A member 6 2.76305
ZC3H11A zinc finger CCCH-type containing 11A 2.64759
SNORA77 small nucleolar RNA, H/ACA box 77 2.64759
SNRPE small nuclear ribonucleoprotein polypeptide E 2.64759
OPTC opticin 2.64759
LAX1 lymphocyte transmembrane adaptor 1 2.64759
ZBED6 zinc finger, BED-type containing 6 2.64759
LINC00303 long intergenic non-protein coding RNA 303 2.64759
SOX13 SRY (sex determining region Y)-box 13 2.64759
LINC00260 long intergenic non-protein coding RNA 260 2.64759
PRELP proline/arginine-rich end leucine-rich repeat protein 2.64759
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 2.64759
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.14116
NAV1 neuron navigator 1 2.14116
MIR1231 microRNA 1231 2.14116
MIR5191 microRNA 5191 2.14116
LINC00467 long intergenic non-protein coding RNA 467 2.12703
TRAF5 TNF receptor-associated factor 5 2.12703
RD3 retinal degeneration 3 2.12703

low copy number

Symbol Name Standardized Value
TRAV20 T cell receptor alpha variable 20 -2.86689
TRD T cell receptor delta locus -2.85728
TRA T cell receptor alpha locus -2.83328
TRGC2 T cell receptor gamma constant 2 -2.83274
TRAC T cell receptor alpha constant -2.8212
TRDC T cell receptor delta constant -2.80776
TARP TCR gamma alternate reading frame protein -2.79573
STS steroid sulfatase (microsomal), isozyme S -2.7778