STOCK1N-35874-6583 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the STOCK1N-35874-6583 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARFIP1 ADP-ribosylation factor interacting protein 1
ASPH aspartate beta-hydroxylase
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BAX BCL2-associated X protein
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BTBD7 BTB (POZ) domain containing 7
C14ORF1 chromosome 14 open reading frame 1
C6ORF62 chromosome 6 open reading frame 62
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CHAF1A chromatin assembly factor 1, subunit A (p150)
CLN3 ceroid-lipofuscinosis, neuronal 3
COMMD10 COMM domain containing 10
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL3 chemokine (C-X-C motif) ligand 3
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCAF11 DDB1 and CUL4 associated factor 11
DCN decorin
DLG5 discs, large homolog 5 (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENO1 enolase 1, (alpha)
EP300 E1A binding protein p300
EXOC7 exocyst complex component 7
FHL1 four and a half LIM domains 1
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLE1 GLE1 RNA export mediator
GLUL glutamate-ammonia ligase
GTSE1 G-2 and S-phase expressed 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA8 heat shock 70kDa protein 8
IGFBP3 insulin-like growth factor binding protein 3
INPP5K inositol polyphosphate-5-phosphatase K
KDM4A lysine (K)-specific demethylase 4A
LDLR low density lipoprotein receptor
LIN7B lin-7 homolog B (C. elegans)
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCM4 minichromosome maintenance complex component 4
MDC1 mediator of DNA-damage checkpoint 1
MET MET proto-oncogene, receptor tyrosine kinase
MOB3B MOB kinase activator 3B
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCK1 NCK adaptor protein 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFYA nuclear transcription factor Y, alpha
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PDE4DIP phosphodiesterase 4D interacting protein
PEX6 peroxisomal biogenesis factor 6
PHF2 PHD finger protein 2
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
POLG polymerase (DNA directed), gamma
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCH protein kinase C, eta
PTBP1 polypyrimidine tract binding protein 1
RAB3B RAB3B, member RAS oncogene family
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
SCYL2 SCY1-like 2 (S. cerevisiae)
SIK3 SIK family kinase 3
SIRT6 sirtuin 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC41A3 solute carrier family 41, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPATS2L spermatogenesis associated, serine-rich 2-like
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STIP1 stress-induced phosphoprotein 1
TEX40 testis expressed 40
TMED2 transmembrane emp24 domain trafficking protein 2
TRADD TNFRSF1A-associated via death domain
U2AF2 U2 small nuclear RNA auxiliary factor 2
UBE4B ubiquitination factor E4B
WDR48 WD repeat domain 48
WWC2 WW and C2 domain containing 2
WWOX WW domain containing oxidoreductase
XYLT2 xylosyltransferase II
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36 ZFP36 ring finger protein
ZNF254 zinc finger protein 254

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADGRB2 adhesion G protein-coupled receptor B2
ALPK1 alpha-kinase 1
AMDHD2 amidohydrolase domain containing 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA10 annexin A10
ANXA2P3 annexin A2 pseudogene 3
APH1B APH1B gamma secretase subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP24 Rho GTPase activating protein 24
ARMCX2 armadillo repeat containing, X-linked 2
ARSJ arylsulfatase family, member J
ASTE1 asteroid homolog 1 (Drosophila)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C11ORF80 chromosome 11 open reading frame 80
C3 complement component 3
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK18 cyclin-dependent kinase 18
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CNTN1 contactin 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND2D DENN/MADD domain containing 2D
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAT4 FAT atypical cadherin 4
FBXL6 F-box and leucine-rich repeat protein 6
FHOD3 formin homology 2 domain containing 3
FIG4 FIG4 phosphoinositide 5-phosphatase
FLRT3 fibronectin leucine rich transmembrane protein 3
GHR growth hormone receptor
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GREB1L growth regulation by estrogen in breast cancer-like
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AJ histone cluster 1, H2aj
HOXC5 homeobox C5
IDI2-AS1 IDI2 antisense RNA 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0922 KIAA0922
KLHL3 kelch-like family member 3
LINC00341 long intergenic non-protein coding RNA 341
LMCD1 LIM and cysteine-rich domains 1
MANBA mannosidase, beta A, lysosomal
MAPK12 mitogen-activated protein kinase 12
MBD5 methyl-CpG binding domain protein 5
MRPL52 mitochondrial ribosomal protein L52
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
NDP Norrie disease (pseudoglioma)
ONECUT2 one cut homeobox 2
PALMD palmdelphin
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEX26 peroxisomal biogenesis factor 26
PLAC1 placenta-specific 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCH2 phospholipase C, eta 2
PRICKLE3 prickle homolog 3 (Drosophila)
PROL1 proline rich, lacrimal 1
PRSS16 protease, serine, 16 (thymus)
RAP1GAP2 RAP1 GTPase activating protein 2
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC22A18 solute carrier family 22, member 18
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAI2 snail family zinc finger 2
SPAG16 sperm associated antigen 16
SYT17 synaptotagmin XVII
TMEM180 transmembrane protein 180
TMEM184C transmembrane protein 184C
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TTN titin
TUBA3C tubulin, alpha 3c
UNC13A unc-13 homolog A (C. elegans)
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WASF1 WAS protein family, member 1
WDR91 WD repeat domain 91
ZBTB3 zinc finger and BTB domain containing 3
ZNF165 zinc finger protein 165
ZNF205 zinc finger protein 205
ZNF358 zinc finger protein 358