STOCK1N-35215-6422 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the STOCK1N-35215-6422 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABHD4 abhydrolase domain containing 4
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKT3 v-akt murine thymoma viral oncogene homolog 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOE apolipoprotein E
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATAT1 alpha tubulin acetyltransferase 1
ATF3 activating transcription factor 3
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BIN1 bridging integrator 1
C1ORF54 chromosome 1 open reading frame 54
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CD22 CD22 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL3A1 collagen, type III, alpha 1
CREM cAMP responsive element modulator
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DDIT3 DNA-damage-inducible transcript 3
DIO2 deiodinase, iodothyronine, type II
DMTN dematin actin binding protein
DTNA dystrobrevin, alpha
DUSP13 dual specificity phosphatase 13
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FBXO2 F-box protein 2
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
GABARAPL1 GABA(A) receptor-associated protein like 1
GCLM glutamate-cysteine ligase, modifier subunit
GMPR guanosine monophosphate reductase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GOSR2 golgi SNAP receptor complex member 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICA1 islet cell autoantigen 1, 69kDa
IL6R interleukin 6 receptor
IL9R interleukin 9 receptor
INO80B INO80 complex subunit B
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLHL24 kelch-like family member 24
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT8 keratin 8, type II
LAMC2 laminin, gamma 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MMP13 matrix metallopeptidase 13
MYH14 myosin, heavy chain 14, non-muscle
N4BP2L2 NEDD4 binding protein 2-like 2
NCAPH2 non-SMC condensin II complex, subunit H2
NF1 neurofibromin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NGDN neuroguidin, EIF4E binding protein
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUPR1 nuclear protein, transcriptional regulator, 1
OSGIN1 oxidative stress induced growth inhibitor 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHF20 PHD finger protein 20
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PQLC2 PQ loop repeat containing 2
PRDM10 PR domain containing 10
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTPRR protein tyrosine phosphatase, receptor type, R
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAB11B RAB11B, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RGCC regulator of cell cycle
RHBG Rh family, B glycoprotein (gene/pseudogene)
SCAPER S-phase cyclin A-associated protein in the ER
SGPL1 sphingosine-1-phosphate lyase 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SPN sialophorin
TCAF1 TRPM8 channel-associated factor 1
THAP3 THAP domain containing, apoptosis associated protein 3
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TKTL1 transketolase-like 1
TLDC1 TBC/LysM-associated domain containing 1
TMC5 transmembrane channel-like 5
TRIM16 tripartite motif containing 16
TUBA3C tubulin, alpha 3c
TXNRD1 thioredoxin reductase 1
UTRN utrophin
ZBTB7A zinc finger and BTB domain containing 7A
ZDHHC17 zinc finger, DHHC-type containing 17

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ARC activity-regulated cytoskeleton-associated protein
ARMC4 armadillo repeat containing 4
AXIN1 axin 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C2ORF68 chromosome 2 open reading frame 68
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CCDC25 coiled-coil domain containing 25
CCNO cyclin O
CCP110 centriolar coiled coil protein 110kDa
CDC7 cell division cycle 7
COG2 component of oligomeric golgi complex 2
CRMP1 collapsin response mediator protein 1
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAAF2 dynein, axonemal, assembly factor 2
E2F8 E2F transcription factor 8
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMID1 EMI domain containing 1
FAM131A family with sequence similarity 131, member A
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
GDF5 growth differentiation factor 5
GOLGA2P5 golgin A2 pseudogene 5
GPR19 G protein-coupled receptor 19
H2AFJ H2A histone family, member J
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H4C histone cluster 1, H4c
HMGB3P1 high mobility group box 3 pseudogene 1
HOXC13 homeobox C13
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
ITGA10 integrin, alpha 10
KCTD17 potassium channel tetramerization domain containing 17
LINS lines homolog (Drosophila)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LZTR1 leucine-zipper-like transcription regulator 1
MAGEF1 melanoma antigen family F1
MEIS2 Meis homeobox 2
METRN meteorin, glial cell differentiation regulator
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRPL17 mitochondrial ribosomal protein L17
MTMR6 myotubularin related protein 6
MXD3 MAX dimerization protein 3
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NUPL2 nucleoporin like 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PAQR6 progestin and adipoQ receptor family member VI
PCDHB8 protocadherin beta 8
PCNXL4 pecanex-like 4 (Drosophila)
PDE12 phosphodiesterase 12
PEX26 peroxisomal biogenesis factor 26
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCD protein kinase C, delta
PRR15L proline rich 15-like
PTCD2 pentatricopeptide repeat domain 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBM12 RNA binding motif protein 12
RBM4B RNA binding motif protein 4B
RGS16 regulator of G-protein signaling 16
RIBC2 RIB43A domain with coiled-coils 2
RIN1 Ras and Rab interactor 1
RNF38 ring finger protein 38
SLC38A10 solute carrier family 38, member 10
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLIT2 slit homolog 2 (Drosophila)
SRBD1 S1 RNA binding domain 1
SREBF1 sterol regulatory element binding transcription factor 1
SSFA2 sperm specific antigen 2
ST5 suppression of tumorigenicity 5
STON1 stonin 1
SYT17 synaptotagmin XVII
TBL3 transducin (beta)-like 3
TCTN1 tectonic family member 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLR5 toll-like receptor 5
TMEM183A transmembrane protein 183A
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
UBQLN4 ubiquilin 4
UPK3B uroplakin 3B
WRN Werner syndrome, RecQ helicase-like
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF358 zinc finger protein 358
ZSWIM1 zinc finger, SWIM-type containing 1
ZXDC ZXD family zinc finger C