STOCK1N-28457-6906 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the STOCK1N-28457-6906 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALMS1 Alstrom syndrome protein 1
ALPK1 alpha-kinase 1
APLP1 amyloid beta (A4) precursor-like protein 1
APP amyloid beta (A4) precursor protein
ATAD3A ATPase family, AAA domain containing 3A
ATP10A ATPase, class V, type 10A
ATP11B ATPase, class VI, type 11B
ATP9A ATPase, class II, type 9A
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BFSP1 beaded filament structural protein 1, filensin
BLVRA biliverdin reductase A
BRWD1 bromodomain and WD repeat domain containing 1
C14ORF132 chromosome 14 open reading frame 132
C9ORF156 chromosome 9 open reading frame 156
CALML4 calmodulin-like 4
CCPG1 cell cycle progression 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DLX4 distal-less homeobox 4
DRD2 dopamine receptor D2
EGLN3 egl-9 family hypoxia-inducible factor 3
EMID1 EMI domain containing 1
ERCC2 excision repair cross-complementation group 2
F3 coagulation factor III (thromboplastin, tissue factor)
FADS2 fatty acid desaturase 2
FASTKD2 FAST kinase domains 2
FCF1 FCF1 rRNA-processing protein
FILIP1L filamin A interacting protein 1-like
FOXD1 forkhead box D1
FSHB follicle stimulating hormone, beta polypeptide
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GSDMB gasdermin B
HDAC7 histone deacetylase 7
HDLBP high density lipoprotein binding protein
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H4F histone cluster 1, H4f
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
JMJD4 jumonji domain containing 4
JUN jun proto-oncogene
KDM4B lysine (K)-specific demethylase 4B
KREMEN2 kringle containing transmembrane protein 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAPK12 mitogen-activated protein kinase 12
MED28 mediator complex subunit 28
MKS1 Meckel syndrome, type 1
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTA1 metastasis associated 1
MTM1 myotubularin 1
MVP major vault protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MZT2B mitotic spindle organizing protein 2B
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCKIPSD NCK interacting protein with SH3 domain
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NME5 NME/NM23 family member 5
NMT2 N-myristoyltransferase 2
NUP160 nucleoporin 160kDa
OGFR opioid growth factor receptor
PDGFA platelet-derived growth factor alpha polypeptide
PELP1 proline, glutamate and leucine rich protein 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PTMA prothymosin, alpha
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RANBP3 RAN binding protein 3
RELN reelin
RND2 Rho family GTPase 2
RNF19B ring finger protein 19B
S100A4 S100 calcium binding protein A4
SCAPER S-phase cyclin A-associated protein in the ER
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SF3A2 splicing factor 3a, subunit 2, 66kDa
SHANK2 SH3 and multiple ankyrin repeat domains 2
SIAH1 siah E3 ubiquitin protein ligase 1
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC25A44 solute carrier family 25, member 44
SMAD4 SMAD family member 4
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSH3 slingshot protein phosphatase 3
STK11 serine/threonine kinase 11
SYNJ2 synaptojanin 2
TCF3 transcription factor 3
TMEM121 transmembrane protein 121
TPM1 tropomyosin 1 (alpha)
TPMT thiopurine S-methyltransferase
TRAIP TRAF interacting protein
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF276 zinc finger protein 276
ZNF329 zinc finger protein 329
ZNF492 zinc finger protein 492
ZNF668 zinc finger protein 668
ZNF79 zinc finger protein 79
ZNF8 zinc finger protein 8

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
AES amino-terminal enhancer of split
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALG3 ALG3, alpha-1,3- mannosyltransferase
ANKRD36 ankyrin repeat domain 36
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASNA1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
AURKB aurora kinase B
BCL9 B-cell CLL/lymphoma 9
BSG basigin (Ok blood group)
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCNL2 cyclin L2
CDC37 cell division cycle 37
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLCN2 chloride channel, voltage-sensitive 2
CLDND1 claudin domain containing 1
CRIP2 cysteine-rich protein 2
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYBA cytochrome b-245, alpha polypeptide
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCAF13 DDB1 and CUL4 associated factor 13
DDA1 DET1 and DDB1 associated 1
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
EFNA3 ephrin-A3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERF Ets2 repressor factor
ERI3 ERI1 exoribonuclease family member 3
GDE1 glycerophosphodiester phosphodiesterase 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GMIP GEM interacting protein
GOLGA8B golgin A8 family, member B
GPHN gephyrin
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL17RA interleukin 17 receptor A
ILK integrin-linked kinase
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KPTN kaptin (actin binding protein)
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MPDU1 mannose-P-dolichol utilization defect 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PDIA3 protein disulfide isomerase family A, member 3
PGD phosphogluconate dehydrogenase
PHACTR4 phosphatase and actin regulator 4
PLK1 polo-like kinase 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POGK pogo transposable element with KRAB domain
PPAP2C phosphatidic acid phosphatase type 2C
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PSENEN presenilin enhancer gamma secretase subunit
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
QTRT1 queuine tRNA-ribosyltransferase 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF146 ring finger protein 146
S100A7 S100 calcium binding protein A7
SCAMP2 secretory carrier membrane protein 2
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETD8 SET domain containing (lysine methyltransferase) 8
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNX17 sorting nexin 17
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYTL2 synaptotagmin-like 2
TCTA T-cell leukemia translocation altered
TCTN1 tectonic family member 1
TM7SF2 transmembrane 7 superfamily member 2
TMC7 transmembrane channel-like 7
TMEM230 transmembrane protein 230
TMEM254 transmembrane protein 254
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRABD TraB domain containing
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBE2M ubiquitin-conjugating enzyme E2M
USB1 U6 snRNA biogenesis 1
YIPF5 Yip1 domain family, member 5
ZBTB48 zinc finger and BTB domain containing 48
ZFYVE21 zinc finger, FYVE domain containing 21
ZMAT5 zinc finger, matrin-type 5
ZNF282 zinc finger protein 282
ZNF652 zinc finger protein 652