SR-95639A-6632 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the SR-95639A-6632 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARID5A AT rich interactive domain 5A (MRF1-like)
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BLZF1 basic leucine zipper nuclear factor 1
BTN3A2 butyrophilin, subfamily 3, member A2
C17ORF59 chromosome 17 open reading frame 59
C1ORF54 chromosome 1 open reading frame 54
C20ORF195 chromosome 20 open reading frame 195
CERS4 ceramide synthase 4
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLEC11A C-type lectin domain family 11, member A
COL4A6 collagen, type IV, alpha 6
CORO1A coronin, actin binding protein, 1A
CPNE7 copine VII
CRLF1 cytokine receptor-like factor 1
CSF1R colony stimulating factor 1 receptor
DNASE1L3 deoxyribonuclease I-like 3
DRD2 dopamine receptor D2
ELOVL5 ELOVL fatty acid elongase 5
FAM63A family with sequence similarity 63, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF18 fibroblast growth factor 18
FUS FUS RNA binding protein
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GIF gastric intrinsic factor (vitamin B synthesis)
GK glycerol kinase
GLB1L galactosidase, beta 1-like
GLRA3 glycine receptor, alpha 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HAP1 huntingtin-associated protein 1
HBE1 hemoglobin, epsilon 1
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIPK3 homeodomain interacting protein kinase 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA1 homeobox A1
HRASLS2 HRAS-like suppressor 2
HSF1 heat shock transcription factor 1
IGHA1 immunoglobulin heavy constant alpha 1
IGKV3-20 immunoglobulin kappa variable 3-20
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KL klotho
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC157562 uncharacterized LOC157562
LRMP lymphoid-restricted membrane protein
MCF2L MCF.2 cell line derived transforming sequence-like
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MEOX2 mesenchyme homeobox 2
MERTK MER proto-oncogene, tyrosine kinase
MKL1 megakaryoblastic leukemia (translocation) 1
MPPE1 metallophosphoesterase 1
MVD mevalonate (diphospho) decarboxylase
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NEK3 NIMA-related kinase 3
NTNG1 netrin G1
ODAM odontogenic, ameloblast asssociated
PAPPA2 pappalysin 2
PDCD6 programmed cell death 6
PHF20 PHD finger protein 20
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIDD1 p53-induced death domain protein 1
PLA2G1B phospholipase A2, group IB (pancreas)
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
PON1 paraoxonase 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKG1 protein kinase, cGMP-dependent, type I
PSD4 pleckstrin and Sec7 domain containing 4
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RND2 Rho family GTPase 2
RNF43 ring finger protein 43
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL10L ribosomal protein L10-like
RPL35A ribosomal protein L35a
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SKIL SKI-like proto-oncogene
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOS2 son of sevenless homolog 2 (Drosophila)
SPANXC SPANX family, member C
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAPBPL TAP binding protein-like
TFDP3 transcription factor Dp family, member 3
THOC5 THO complex 5
TLR5 toll-like receptor 5
TRAF2 TNF receptor-associated factor 2
TRIM3 tripartite motif containing 3
VCAN versican
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB17 zinc finger and BTB domain containing 17
ZC3H7B zinc finger CCCH-type containing 7B
ZNF81 zinc finger protein 81

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
AGO4 argonaute RISC catalytic component 4
AMT aminomethyltransferase
ANKRD40 ankyrin repeat domain 40
ARMCX2 armadillo repeat containing, X-linked 2
AXIN1 axin 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
C22ORF29 chromosome 22 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CAMKMT calmodulin-lysine N-methyltransferase
CAMTA2 calmodulin binding transcription activator 2
CBX4 chromobox homolog 4
CENPJ centromere protein J
CENPT centromere protein T
CLEC2B C-type lectin domain family 2, member B
CNGB3 cyclic nucleotide gated channel beta 3
COL21A1 collagen, type XXI, alpha 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
CST1 cystatin SN
CTC1 CTS telomere maintenance complex component 1
CUZD1 CUB and zona pellucida-like domains 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
ECM1 extracellular matrix protein 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FGF23 fibroblast growth factor 23
FSTL3 follistatin-like 3 (secreted glycoprotein)
GPR1 G protein-coupled receptor 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
IL2 interleukin 2
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT4 keratin 4, type II
LAX1 lymphocyte transmembrane adaptor 1
LRRC6 leucine rich repeat containing 6
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGEA3 melanoma antigen family A3
MAGEH1 melanoma antigen family H1
MCC mutated in colorectal cancers
MDFI MyoD family inhibitor
MGC12488
MICALL2 MICAL-like 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYH15 myosin, heavy chain 15
NABP1 nucleic acid binding protein 1
NCS1 neuronal calcium sensor 1
OLFML2B olfactomedin-like 2B
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHKG2 phosphorylase kinase, gamma 2 (testis)
PMPCA peptidase (mitochondrial processing) alpha
POLL polymerase (DNA directed), lambda
PRICKLE3 prickle homolog 3 (Drosophila)
PRKX protein kinase, X-linked
PSKH1 protein serine kinase H1
PTDSS2 phosphatidylserine synthase 2
RAB3A RAB3A, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RIBC2 RIB43A domain with coiled-coils 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SH2B1 SH2B adaptor protein 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHROOM2 shroom family member 2
SIRT6 sirtuin 6
SIX3 SIX homeobox 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC46A3 solute carrier family 46, member 3
SPRYD7 SPRY domain containing 7
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAOK1 TAO kinase 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM212 transmembrane protein 212
TMSB15A thymosin beta 15a
TTN titin
WDR25 WD repeat domain 25
WDR4 WD repeat domain 4
WDR46 WD repeat domain 46
WDR62 WD repeat domain 62
ZNF165 zinc finger protein 165
ZNF214 zinc finger protein 214
ZNF230 zinc finger protein 230
ZNF268 zinc finger protein 268
ZNF286A zinc finger protein 286A
ZNF529 zinc finger protein 529
ZNF711 zinc finger protein 711
ZNHIT2 zinc finger, HIT-type containing 2
ZW10 zw10 kinetochore protein