SR-95639A-3272 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the SR-95639A-3272 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ALOX15 arachidonate 15-lipoxygenase
ALOXE3 arachidonate lipoxygenase 3
APC adenomatous polyposis coli
ARL4C ADP-ribosylation factor-like 4C
ASPH aspartate beta-hydroxylase
ATN1 atrophin 1
BLZF1 basic leucine zipper nuclear factor 1
BMP10 bone morphogenetic protein 10
C1QTNF1 C1q and tumor necrosis factor related protein 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD300A CD300a molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CIDEB cell death-inducing DFFA-like effector b
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL1A1 collagen, type I, alpha 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DIO2 deiodinase, iodothyronine, type II
DUSP13 dual specificity phosphatase 13
EXOSC1 exosome component 1
FAM49B family with sequence similarity 49, member B
FSCN1 fascin actin-bundling protein 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOLGA8A golgin A8 family, member A
HFE hemochromatosis
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
INCENP inner centromere protein antigens 135/155kDa
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JUN jun proto-oncogene
KRT83 keratin 83, type II
LGALS8 lectin, galactoside-binding, soluble, 8
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC1 leucine rich repeat containing 1
LTBP2 latent transforming growth factor beta binding protein 2
LTBP4 latent transforming growth factor beta binding protein 4
MAOB monoamine oxidase B
MAST2 microtubule associated serine/threonine kinase 2
MC5R melanocortin 5 receptor
MET MET proto-oncogene, receptor tyrosine kinase
METTL7A methyltransferase like 7A
MFSD11 major facilitator superfamily domain containing 11
MTCP1 mature T-cell proliferation 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFRKB nuclear factor related to kappaB binding protein
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7C1 olfactory receptor, family 7, subfamily C, member 1
PARD6B par-6 family cell polarity regulator beta
PARG poly (ADP-ribose) glycohydrolase
POPDC3 popeye domain containing 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRLH prolactin releasing hormone
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RARA retinoic acid receptor, alpha
RBM5 RNA binding motif protein 5
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RIMS2 regulating synaptic membrane exocytosis 2
RPL10L ribosomal protein L10-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RYR1 ryanodine receptor 1 (skeletal)
SAFB scaffold attachment factor B
SCAND2P SCAN domain containing 2 pseudogene
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC43A3 solute carrier family 43, member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMAD1 SMAD family member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SPHK2 sphingosine kinase 2
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
STYK1 serine/threonine/tyrosine kinase 1
SYMPK symplekin
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFDP3 transcription factor Dp family, member 3
TGM2 transglutaminase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSPYL2 TSPY-like 2
UTRN utrophin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZFHX4 zinc finger homeobox 4
ZNF10 zinc finger protein 10
ZNF154 zinc finger protein 154
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACSF2 acyl-CoA synthetase family member 2
ACTN4 actinin, alpha 4
ADGRG2 adhesion G protein-coupled receptor G2
AFF4 AF4/FMR2 family, member 4
AMPD2 adenosine monophosphate deaminase 2
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ARMC4 armadillo repeat containing 4
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L2 BCL2-like 2
BTBD2 BTB (POZ) domain containing 2
C14ORF93 chromosome 14 open reading frame 93
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CGREF1 cell growth regulator with EF-hand domain 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CSF1R colony stimulating factor 1 receptor
CTNNBIP1 catenin, beta interacting protein 1
CXORF56 chromosome X open reading frame 56
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAAF2 dynein, axonemal, assembly factor 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ERCC2 excision repair cross-complementation group 2
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
GADD45G growth arrest and DNA-damage-inducible, gamma
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR27 G protein-coupled receptor 27
HIST1H2BC histone cluster 1, H2bc
HIST2H2AA3 histone cluster 2, H2aa3
HSPA1L heat shock 70kDa protein 1-like
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT140 intraflagellar transport 140
IGSF1 immunoglobulin superfamily, member 1
IL4R interleukin 4 receptor
IMPACT impact RWD domain protein
INPPL1 inositol polyphosphate phosphatase-like 1
JUNB jun B proto-oncogene
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0754 KIAA0754
KIAA1551 KIAA1551
KIF13B kinesin family member 13B
MSX1 msh homeobox 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
OPN3 opsin 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHA6 protocadherin alpha 6
PEX26 peroxisomal biogenesis factor 26
PGBD5 piggyBac transposable element derived 5
PITX2 paired-like homeodomain 2
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODXL2 podocalyxin-like 2
POLL polymerase (DNA directed), lambda
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PTPRU protein tyrosine phosphatase, receptor type, U
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROM1 retinal outer segment membrane protein 1
RPAP2 RNA polymerase II associated protein 2
RPS14P3 ribosomal protein S14 pseudogene 3
SCN1B sodium channel, voltage gated, type I beta subunit
SETD1B SET domain containing 1B
SFXN1 sideroflexin 1
SIX1 SIX homeobox 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX3 SRY (sex determining region Y)-box 3
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAPPC11 trafficking protein particle complex 11
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VEGFB vascular endothelial growth factor B
WDR4 WD repeat domain 4
WLS wntless Wnt ligand secretion mediator
ZBTB44 zinc finger and BTB domain containing 44
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFHX3 zinc finger homeobox 3
ZNF227 zinc finger protein 227
ZNF701 zinc finger protein 701