SHP2 signaling Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/85755aa4-6195-11e5-8ac5-06603eb7f303
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Genes

53 proteins participating in the SHP2 signaling pathway from the PID Pathways dataset.

Symbol Name
ANGPT1 angiopoietin 1
ARHGAP35 Rho GTPase activating protein 35
BDNF brain-derived neurotrophic factor
EGF epidermal growth factor
EGFR epidermal growth factor receptor
FRS2 fibroblast growth factor receptor substrate 2
FRS3 fibroblast growth factor receptor substrate 3
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGF1R insulin-like growth factor 1 receptor
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IRS1 insulin receptor substrate 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KDR kinase insert domain receptor
LCK LCK proto-oncogene, Src family tyrosine kinase
LMO4 LIM domain only 4
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
NGF nerve growth factor (beta polypeptide)
NOS3 nitric oxide synthase 3 (endothelial cell)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RHOA ras homolog family member A
SDC2 syndecan 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
STAT1 signal transducer and activator of transcription 1, 91kDa
TEK TEK tyrosine kinase, endothelial