SC-560-6913 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the SC-560-6913 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
ANKRD12 ankyrin repeat domain 12
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARMC9 armadillo repeat containing 9
BCL9 B-cell CLL/lymphoma 9
BRWD1 bromodomain and WD repeat domain containing 1
CASD1 CAS1 domain containing 1
CCDC88C coiled-coil domain containing 88C
CCNG2 cyclin G2
CES2 carboxylesterase 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CREM cAMP responsive element modulator
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DBR1 debranching RNA lariats 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DLX4 distal-less homeobox 4
DOCK9 dedicator of cytokinesis 9
EEA1 early endosome antigen 1
EIF5B eukaryotic translation initiation factor 5B
ELOVL2 ELOVL fatty acid elongase 2
EVI5 ecotropic viral integration site 5
FAM168A family with sequence similarity 168, member A
FAM169A family with sequence similarity 169, member A
FAM50B family with sequence similarity 50, member B
FOSL2 FOS-like antigen 2
GATA2 GATA binding protein 2
GLCE glucuronic acid epimerase
GLTSCR1L GLTSCR1-like
GRTP1 growth hormone regulated TBC protein 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
H2AFY2 H2A histone family, member Y2
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HCFC2 host cell factor C2
HIST1H4C histone cluster 1, H4c
HOXC10 homeobox C10
HPSE heparanase
IPO9 importin 9
ITGB5 integrin, beta 5
JMJD1C jumonji domain containing 1C
KCTD13 potassium channel tetramerization domain containing 13
KIAA0930 KIAA0930
KIF16B kinesin family member 16B
KLHL23 kelch-like family member 23
KLHL24 kelch-like family member 24
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MALT1 MALT1 paracaspase
MAN1A1 mannosidase, alpha, class 1A, member 1
MTRF1 mitochondrial translational release factor 1
NCAPH2 non-SMC condensin II complex, subunit H2
NCKAP1 NCK-associated protein 1
NEBL nebulette
NNT nicotinamide nucleotide transhydrogenase
NPIPB15 nuclear pore complex interacting protein family, member B15
NUP62CL nucleoporin 62kDa C-terminal like
OXTR oxytocin receptor
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH9 protocadherin 9
PCNXL4 pecanex-like 4 (Drosophila)
PLA2G10 phospholipase A2, group X
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POFUT1 protein O-fucosyltransferase 1
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB40B RAB40B, member RAS oncogene family
RABGGTB Rab geranylgeranyltransferase, beta subunit
RCE1 Ras converting CAAX endopeptidase 1
RRAGD Ras-related GTP binding D
RUFY3 RUN and FYVE domain containing 3
SAFB2 scaffold attachment factor B2
SESN1 sestrin 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIRT6 sirtuin 6
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SP100 SP100 nuclear antigen
SPATA2L spermatogenesis associated 2-like
SPATA5L1 spermatogenesis associated 5-like 1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
SRSF8 serine/arginine-rich splicing factor 8
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK3 serine/threonine kinase 3
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYT1 synaptotagmin I
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TGIF1 TGFB-induced factor homeobox 1
TJP1 tight junction protein 1
TLE4 transducin-like enhancer of split 4
TM7SF3 transmembrane 7 superfamily member 3
TMF1 TATA element modulatory factor 1
TRIM23 tripartite motif containing 23
TSFM Ts translation elongation factor, mitochondrial
WDR48 WD repeat domain 48
WDR60 WD repeat domain 60
WDR7 WD repeat domain 7
WRN Werner syndrome, RecQ helicase-like
ZFP30 ZFP30 zinc finger protein
ZNF200 zinc finger protein 200
ZNF580 zinc finger protein 580

decreased expression

Symbol Name
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARL2 ADP-ribosylation factor-like 2
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHD1 bromo adjacent homology domain containing 1
C22ORF29 chromosome 22 open reading frame 29
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPNS1 calpain, small subunit 1
CCNO cyclin O
CDK9 cyclin-dependent kinase 9
CES3 carboxylesterase 3
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLIC3 chloride intracellular channel 3
CORO1A coronin, actin binding protein, 1A
CPPED1 calcineurin-like phosphoesterase domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAP death-associated protein
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERF Ets2 repressor factor
FAM192A family with sequence similarity 192, member A
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GLB1L2 galactosidase, beta 1-like 2
GPX4 glutathione peroxidase 4
HIST1H2AJ histone cluster 1, H2aj
INF2 inverted formin, FH2 and WH2 domain containing
IRF9 interferon regulatory factor 9
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM5C lysine (K)-specific demethylase 5C
KLHDC3 kelch domain containing 3
LOXL1 lysyl oxidase-like 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGLL monoglyceride lipase
MITF microphthalmia-associated transcription factor
MLF2 myeloid leukemia factor 2
MPDU1 mannose-P-dolichol utilization defect 1
MT3 metallothionein 3
MVD mevalonate (diphospho) decarboxylase
NRBP1 nuclear receptor binding protein 1
NUPL2 nucleoporin like 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVGP1 oviductal glycoprotein 1, 120kDa
PGD phosphogluconate dehydrogenase
PHACTR4 phosphatase and actin regulator 4
PLEK2 pleckstrin 2
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POGK pogo transposable element with KRAB domain
PPAP2C phosphatidic acid phosphatase type 2C
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRKCD protein kinase C, delta
PRMT1 protein arginine methyltransferase 1
PRMT5 protein arginine methyltransferase 5
PRR3 proline rich 3
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSKH1 protein serine kinase H1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RNF113A ring finger protein 113A
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SPAG7 sperm associated antigen 7
STX10 syntaxin 10
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCTN2 tectonic family member 2
TGS1 trimethylguanosine synthase 1
TH tyrosine hydroxylase
TM7SF2 transmembrane 7 superfamily member 2
TMEM230 transmembrane protein 230
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPST2 tyrosylprotein sulfotransferase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN1 tetraspanin 1
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2M ubiquitin-conjugating enzyme E2M
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
VAV1 vav 1 guanine nucleotide exchange factor
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF331 zinc finger protein 331
ZNF665 zinc finger protein 665
ZNF767P zinc finger family member 767, pseudogene