Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the SC-560-6865 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
ACTA2 | actin, alpha 2, smooth muscle, aorta |
AIM1L | absent in melanoma 1-like |
AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) |
AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
APOL6 | apolipoprotein L, 6 |
ATP10D | ATPase, class V, type 10D |
BCL2L1 | BCL2-like 1 |
BCOR | BCL6 corepressor |
BDNF | brain-derived neurotrophic factor |
BEX4 | brain expressed, X-linked 4 |
BICD1 | bicaudal D homolog 1 (Drosophila) |
BTG2 | BTG family, member 2 |
BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
C14ORF79 | chromosome 14 open reading frame 79 |
C1ORF54 | chromosome 1 open reading frame 54 |
C9ORF116 | chromosome 9 open reading frame 116 |
CDC14A | cell division cycle 14A |
CDC40 | cell division cycle 40 |
COL21A1 | collagen, type XXI, alpha 1 |
CUL4B | cullin 4B |
CXCL3 | chemokine (C-X-C motif) ligand 3 |
CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
DAGLA | diacylglycerol lipase, alpha |
DALRD3 | DALR anticodon binding domain containing 3 |
DENND2A | DENN/MADD domain containing 2A |
DVL2 | dishevelled segment polarity protein 2 |
EPN1 | epsin 1 |
EXT1 | exostosin glycosyltransferase 1 |
FAM174B | family with sequence similarity 174, member B |
FHL1 | four and a half LIM domains 1 |
FOXE1 | forkhead box E1 |
FRS3 | fibroblast growth factor receptor substrate 3 |
FSD1 | fibronectin type III and SPRY domain containing 1 |
GATA3 | GATA binding protein 3 |
GBX2 | gastrulation brain homeobox 2 |
GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
GMEB2 | glucocorticoid modulatory element binding protein 2 |
GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
GPATCH2L | G patch domain containing 2-like |
GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
HDAC5 | histone deacetylase 5 |
HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
HIST1H2AJ | histone cluster 1, H2aj |
HIST1H3G | histone cluster 1, H3g |
HSPA4 | heat shock 70kDa protein 4 |
IGF1R | insulin-like growth factor 1 receptor |
IL15RA | interleukin 15 receptor, alpha |
ITPKC | inositol-trisphosphate 3-kinase C |
LRP6 | low density lipoprotein receptor-related protein 6 |
MAPK7 | mitogen-activated protein kinase 7 |
MCM4 | minichromosome maintenance complex component 4 |
MET | MET proto-oncogene, receptor tyrosine kinase |
MOB3B | MOB kinase activator 3B |
MYOZ3 | myozenin 3 |
NDNF | neuron-derived neurotrophic factor |
NDP | Norrie disease (pseudoglioma) |
NFYC | nuclear transcription factor Y, gamma |
NNT | nicotinamide nucleotide transhydrogenase |
NPR3 | natriuretic peptide receptor 3 |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
PAPPA2 | pappalysin 2 |
PDPK1 | 3-phosphoinositide dependent protein kinase 1 |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
PRICKLE3 | prickle homolog 3 (Drosophila) |
PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
PTBP3 | polypyrimidine tract binding protein 3 |
PTPN2 | protein tyrosine phosphatase, non-receptor type 2 |
RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
RBM34 | RNA binding motif protein 34 |
REEP2 | receptor accessory protein 2 |
RNF146 | ring finger protein 146 |
SBF1 | SET binding factor 1 |
SCN10A | sodium channel, voltage gated, type X alpha subunit |
SH2B1 | SH2B adaptor protein 1 |
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
SOX15 | SRY (sex determining region Y)-box 15 |
SPN | sialophorin |
SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
STIP1 | stress-induced phosphoprotein 1 |
SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
TAOK2 | TAO kinase 2 |
TDRD3 | tudor domain containing 3 |
TFDP1 | transcription factor Dp-1 |
TM2D1 | TM2 domain containing 1 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TPM2 | tropomyosin 2 (beta) |
TRIO | trio Rho guanine nucleotide exchange factor |
TUSC3 | tumor suppressor candidate 3 |
VIPR2 | vasoactive intestinal peptide receptor 2 |
WDR1 | WD repeat domain 1 |
WNT7A | wingless-type MMTV integration site family, member 7A |
YEATS4 | YEATS domain containing 4 |
ZC3H7B | zinc finger CCCH-type containing 7B |
ZNF174 | zinc finger protein 174 |
Symbol | Name |
---|---|
AATK | apoptosis-associated tyrosine kinase |
ACOT8 | acyl-CoA thioesterase 8 |
ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
ADAP2 | ArfGAP with dual PH domains 2 |
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
ARID5A | AT rich interactive domain 5A (MRF1-like) |
ARSA | arylsulfatase A |
ATP4B | ATPase, H+/K+ exchanging, beta polypeptide |
AVPR1B | arginine vasopressin receptor 1B |
BCAS3 | breast carcinoma amplified sequence 3 |
BFSP1 | beaded filament structural protein 1, filensin |
C3 | complement component 3 |
C5ORF45 | chromosome 5 open reading frame 45 |
C7ORF43 | chromosome 7 open reading frame 43 |
C8B | complement component 8, beta polypeptide |
CCDC88C | coiled-coil domain containing 88C |
CCDC9 | coiled-coil domain containing 9 |
CCL22 | chemokine (C-C motif) ligand 22 |
CD300C | CD300c molecule |
CDK20 | cyclin-dependent kinase 20 |
CFAP44 | cilia and flagella associated protein 44 |
CGREF1 | cell growth regulator with EF-hand domain 1 |
CLCN6 | chloride channel, voltage-sensitive 6 |
CLDN15 | claudin 15 |
CNPY4 | canopy FGF signaling regulator 4 |
CNTFR | ciliary neurotrophic factor receptor |
CSRNP3 | cysteine-serine-rich nuclear protein 3 |
CTF1 | cardiotrophin 1 |
CXORF21 | chromosome X open reading frame 21 |
CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
EGFL7 | EGF-like-domain, multiple 7 |
ELP3 | elongator acetyltransferase complex subunit 3 |
EPHA4 | EPH receptor A4 |
ERCC2 | excision repair cross-complementation group 2 |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FAM186A | family with sequence similarity 186, member A |
FKBP1B | FK506 binding protein 1B, 12.6 kDa |
FOXC1 | forkhead box C1 |
GUCA1B | guanylate cyclase activator 1B (retina) |
HDAC7 | histone deacetylase 7 |
HLA-DMA | major histocompatibility complex, class II, DM alpha |
HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
IL17RA | interleukin 17 receptor A |
IMPACT | impact RWD domain protein |
KIAA1324 | KIAA1324 |
KLK1 | kallikrein 1 |
MEOX1 | mesenchyme homeobox 1 |
MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
MILR1 | mast cell immunoglobulin-like receptor 1 |
MIP | major intrinsic protein of lens fiber |
MUTYH | mutY homolog |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NME5 | NME/NM23 family member 5 |
OSGIN1 | oxidative stress induced growth inhibitor 1 |
OSMR | oncostatin M receptor |
PAQR5 | progestin and adipoQ receptor family member V |
PARP3 | poly (ADP-ribose) polymerase family, member 3 |
PARP6 | poly (ADP-ribose) polymerase family, member 6 |
PHOX2B | paired-like homeobox 2b |
PPT2 | palmitoyl-protein thioesterase 2 |
PRR15L | proline rich 15-like |
PTPRE | protein tyrosine phosphatase, receptor type, E |
RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
RWDD2A | RWD domain containing 2A |
S100A3 | S100 calcium binding protein A3 |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SECISBP2 | SECIS binding protein 2 |
SELPLG | selectin P ligand |
SH3BGR | SH3 domain binding glutamate-rich protein |
SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
SPTBN2 | spectrin, beta, non-erythrocytic 2 |
TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
TBX19 | T-box 19 |
TESPA1 | thymocyte expressed, positive selection associated 1 |
TIMP4 | TIMP metallopeptidase inhibitor 4 |
TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
TMPRSS6 | transmembrane protease, serine 6 |
TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
WDR4 | WD repeat domain 4 |
ZFP69B | ZFP69 zinc finger protein B |
ZNF219 | zinc finger protein 219 |
ZNF671 | zinc finger protein 671 |
ZNF747 | zinc finger protein 747 |