SC-19220-7095 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the SC-19220-7095 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ATG2A autophagy related 2A
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B9D1 B9 protein domain 1
BBS4 Bardet-Biedl syndrome 4
BRAP BRCA1 associated protein
BTBD7 BTB (POZ) domain containing 7
BTN3A1 butyrophilin, subfamily 3, member A1
C17ORF75 chromosome 17 open reading frame 75
C20ORF27 chromosome 20 open reading frame 27
C5ORF28 chromosome 5 open reading frame 28
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CASKIN2 CASK interacting protein 2
CCDC93 coiled-coil domain containing 93
CEP164 centrosomal protein 164kDa
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPT2 carnitine palmitoyltransferase 2
CTGF connective tissue growth factor
CUL9 cullin 9
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DST dystonin
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGLN2 egl-9 family hypoxia-inducible factor 2
FKBPL FK506 binding protein like
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPALPP1 GPALPP motifs containing 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAUS6 HAUS augmin-like complex, subunit 6
HHEX hematopoietically expressed homeobox
HLX H2.0-like homeobox
HNMT histamine N-methyltransferase
IL1RL1 interleukin 1 receptor-like 1
ISG20 interferon stimulated exonuclease gene 20kDa
ITFG2 integrin alpha FG-GAP repeat containing 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA0141 KIAA0141
KLC2 kinesin light chain 2
KLF12 Kruppel-like factor 12
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP4 microtubule-associated protein 4
MCAM melanoma cell adhesion molecule
MDC1 mediator of DNA-damage checkpoint 1
MT1E metallothionein 1E
MTF2 metal response element binding transcription factor 2
NBEAL2 neurobeachin-like 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NNMT nicotinamide N-methyltransferase
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUP50 nucleoporin 50kDa
OCEL1 occludin/ELL domain containing 1
ORAI2 ORAI calcium release-activated calcium modulator 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PBLD phenazine biosynthesis-like protein domain containing
PHTF1 putative homeodomain transcription factor 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
RAB29 RAB29, member RAS oncogene family
RANBP17 RAN binding protein 17
RANGAP1 Ran GTPase activating protein 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RNMT RNA (guanine-7-) methyltransferase
RPL31 ribosomal protein L31
RPS10P5 ribosomal protein S10 pseudogene 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SERBP1 SERPINE1 mRNA binding protein 1
SIK3 SIK family kinase 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A44 solute carrier family 25, member 44
SLC31A1 solute carrier family 31 (copper transporter), member 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SMG5 SMG5 nonsense mediated mRNA decay factor
SNX1 sorting nexin 1
SPDEF SAM pointed domain containing ETS transcription factor
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TBC1D5 TBC1 domain family, member 5
TBRG4 transforming growth factor beta regulator 4
TGM2 transglutaminase 2
TMEM2 transmembrane protein 2
TMEM38B transmembrane protein 38B
TNPO2 transportin 2
TPMT thiopurine S-methyltransferase
TRIM2 tripartite motif containing 2
TRRAP transformation/transcription domain-associated protein
TTC33 tetratricopeptide repeat domain 33
UBE2I ubiquitin-conjugating enzyme E2I
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID3B AT rich interactive domain 3B (BRIGHT-like)
AXIN1 axin 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCKDK branched chain ketoacid dehydrogenase kinase
BCL2L2 BCL2-like 2
BCL7C B-cell CLL/lymphoma 7C
BCORL1 BCL6 corepressor-like 1
BSPRY B-box and SPRY domain containing
C12ORF49 chromosome 12 open reading frame 49
C16ORF62 chromosome 16 open reading frame 62
CCP110 centriolar coiled coil protein 110kDa
CEMIP cell migration inducing protein, hyaluronan binding
CFAP44 cilia and flagella associated protein 44
CHKB choline kinase beta
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CUTC cutC copper transporter
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DUSP9 dual specificity phosphatase 9
ERCC2 excision repair cross-complementation group 2
FBXO46 F-box protein 46
FGD6 FYVE, RhoGEF and PH domain containing 6
GAMT guanidinoacetate N-methyltransferase
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HPSE heparanase
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL6 interleukin 6
IRF9 interferon regulatory factor 9
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
KIAA0355 KIAA0355
KIAA1551 KIAA1551
KLF2 Kruppel-like factor 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
MBTD1 mbt domain containing 1
MCTP1 multiple C2 domains, transmembrane 1
MFSD11 major facilitator superfamily domain containing 11
MGC12488
MOSPD3 motile sperm domain containing 3
MRPL28 mitochondrial ribosomal protein L28
MTMR14 myotubularin related protein 14
MYO1E myosin IE
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAQR4 progestin and adipoQ receptor family member IV
PARD6A par-6 family cell polarity regulator alpha
PECR peroxisomal trans-2-enoyl-CoA reductase
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRMT7 protein arginine methyltransferase 7
PROSER1 proline and serine rich 1
PSENEN presenilin enhancer gamma secretase subunit
PYCARD PYD and CARD domain containing
RAB3A RAB3A, member RAS oncogene family
RBL1 retinoblastoma-like 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RNF123 ring finger protein 123
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPH3AL rabphilin 3A-like (without C2 domains)
RPUSD2 RNA pseudouridylate synthase domain containing 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNX1-IT1 RUNX1 intronic transcript 1
SDC3 syndecan 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TAGLN3 transgelin 3
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TESK2 testis-specific kinase 2
THAP7 THAP domain containing 7
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM177 transmembrane protein 177
TMEM62 transmembrane protein 62
TPK1 thiamin pyrophosphokinase 1
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TTC26 tetratricopeptide repeat domain 26
TXNL4B thioredoxin-like 4B
VEZT vezatin, adherens junctions transmembrane protein
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZC3H12A zinc finger CCCH-type containing 12A
ZMAT5 zinc finger, matrin-type 5
ZNF267 zinc finger protein 267
ZNF350 zinc finger protein 350
ZSCAN16 zinc finger and SCAN domain containing 16