SC-19220-7060 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the SC-19220-7060 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP17A A kinase (PRKA) anchor protein 17A
ALS2CL ALS2 C-terminal like
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP44 Rho GTPase activating protein 44
ASB9 ankyrin repeat and SOCS box containing 9
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AXIN1 axin 1
C10ORF95 chromosome 10 open reading frame 95
C2ORF68 chromosome 2 open reading frame 68
CC2D1A coiled-coil and C2 domain containing 1A
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK18 cyclin-dependent kinase 18
CLTA clathrin, light chain A
COL1A1 collagen, type I, alpha 1
CTSF cathepsin F
DGKG diacylglycerol kinase, gamma 90kDa
DGKQ diacylglycerol kinase, theta 110kDa
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
ELN elastin
EPS8L1 EPS8-like 1
FAM118A family with sequence similarity 118, member A
FAM155B family with sequence similarity 155, member B
FBXL18 F-box and leucine-rich repeat protein 18
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GATA2 GATA binding protein 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HAUS2 HAUS augmin-like complex, subunit 2
HLA-DMA major histocompatibility complex, class II, DM alpha
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
IFT122 intraflagellar transport 122
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INO80B INO80 complex subunit B
IQCK IQ motif containing K
IRF5 interferon regulatory factor 5
KIAA0319L KIAA0319-like
LIN7B lin-7 homolog B (C. elegans)
LMF2 lipase maturation factor 2
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MED25 mediator complex subunit 25
MFSD11 major facilitator superfamily domain containing 11
MMP2 matrix metallopeptidase 2
MRPS12 mitochondrial ribosomal protein S12
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOS1 nitric oxide synthase 1 (neuronal)
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
OGFR opioid growth factor receptor
PBX2 pre-B-cell leukemia homeobox 2
PEAK1 pseudopodium-enriched atypical kinase 1
PER1 period circadian clock 1
PEX5 peroxisomal biogenesis factor 5
PHF20 PHD finger protein 20
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA2 plexin A2
POFUT1 protein O-fucosyltransferase 1
PRLR prolactin receptor
PRPH peripherin
RAB11B RAB11B, member RAS oncogene family
RASAL2 RAS protein activator like 2
RBM3 RNA binding motif (RNP1, RRM) protein 3
RER1 retention in endoplasmic reticulum sorting receptor 1
RNF126P1 ring finger protein 126 pseudogene 1
S100A13 S100 calcium binding protein A13
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1 signal-induced proliferation-associated 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome)
ST5 suppression of tumorigenicity 5
STAT5A signal transducer and activator of transcription 5A
STS steroid sulfatase (microsomal), isozyme S
SYMPK symplekin
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TLE4 transducin-like enhancer of split 4
TLN2 talin 2
TULP3 tubby like protein 3
USP20 ubiquitin specific peptidase 20
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WWOX WW domain containing oxidoreductase
ZFAND6 zinc finger, AN1-type domain 6
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF117 zinc finger protein 117
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTN4 actinin, alpha 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANXA2P3 annexin A2 pseudogene 3
ARHGAP5 Rho GTPase activating protein 5
ATAD5 ATPase family, AAA domain containing 5
BGLAP bone gamma-carboxyglutamate (gla) protein
C12ORF29 chromosome 12 open reading frame 29
C17ORF80 chromosome 17 open reading frame 80
CBX8 chromobox homolog 8
CD302 CD302 molecule
CENPC centromere protein C
CGREF1 cell growth regulator with EF-hand domain 1
CHIC2 cysteine-rich hydrophobic domain 2
CHKB choline kinase beta
CYBA cytochrome b-245, alpha polypeptide
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DEPDC5 DEP domain containing 5
DGAT1 diacylglycerol O-acyltransferase 1
DNAAF2 dynein, axonemal, assembly factor 2
DSP desmoplakin
ELOVL4 ELOVL fatty acid elongase 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERO1L ERO1-like (S. cerevisiae)
FANCL Fanconi anemia, complementation group L
FBXO22 F-box protein 22
FCHSD2 FCH and double SH3 domains 2
FGL1 fibrinogen-like 1
FKBP5 FK506 binding protein 5
FOXD1 forkhead box D1
FRMD1 FERM domain containing 1
FRS2 fibroblast growth factor receptor substrate 2
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBAS glioblastoma amplified sequence
GLCE glucuronic acid epimerase
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IRF9 interferon regulatory factor 9
JMJD4 jumonji domain containing 4
KIF13A kinesin family member 13A
KIF20B kinesin family member 20B
KLHL25 kelch-like family member 25
LINC00339 long intergenic non-protein coding RNA 339
LMAN1 lectin, mannose-binding, 1
LOC157562 uncharacterized LOC157562
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYPD1 LY6/PLAUR domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MCRS1 microspherule protein 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTCP1 mature T-cell proliferation 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL5 myosin, light chain 5, regulatory
NECAB3 N-terminal EF-hand calcium binding protein 3
NME5 NME/NM23 family member 5
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
PCDHGB5 protocadherin gamma subfamily B, 5
PGBD5 piggyBac transposable element derived 5
PITX2 paired-like homeodomain 2
PLK2 polo-like kinase 2
PMCH pro-melanin-concentrating hormone
POLL polymerase (DNA directed), lambda
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRICKLE3 prickle homolog 3 (Drosophila)
PTK6 protein tyrosine kinase 6
PTPRS protein tyrosine phosphatase, receptor type, S
RAB40C RAB40C, member RAS oncogene family
RP2 retinitis pigmentosa 2 (X-linked recessive)
SAV1 salvador family WW domain containing protein 1
SEC24B SEC24 family member B
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEPHS2 selenophosphate synthetase 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SOAT1 sterol O-acyltransferase 1
SPAG1 sperm associated antigen 1
SYCP2 synaptonemal complex protein 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAGLN transgelin
TEP1 telomerase-associated protein 1
TMC7 transmembrane channel-like 7
TPST2 tyrosylprotein sulfotransferase 2
TRABD TraB domain containing
TRIM36 tripartite motif containing 36
TSPYL1 TSPY-like 1
USP25 ubiquitin specific peptidase 25
WDR25 WD repeat domain 25
WLS wntless Wnt ligand secretion mediator
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF137P zinc finger protein 137, pseudogene
ZNF551 zinc finger protein 551
ZNF586 zinc finger protein 586
ZNF76 zinc finger protein 76