SB-202190-7058 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the SB-202190-7058 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD8 abhydrolase domain containing 8
ACADSB acyl-CoA dehydrogenase, short/branched chain
AGFG2 ArfGAP with FG repeats 2
AGRN agrin
AMBRA1 autophagy/beclin-1 regulator 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ATG3 autophagy related 3
ATP9B ATPase, class II, type 9B
BAIAP2 BAI1-associated protein 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BMP2K BMP2 inducible kinase
BRD1 bromodomain containing 1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CASKIN2 CASK interacting protein 2
CDK10 cyclin-dependent kinase 10
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CENPT centromere protein T
CHPF chondroitin polymerizing factor
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCN6 chloride channel, voltage-sensitive 6
CNTNAP1 contactin associated protein 1
DBF4B DBF4 zinc finger B
DGCR2 DiGeorge syndrome critical region gene 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
E2F4 E2F transcription factor 4, p107/p130-binding
EFNB1 ephrin-B1
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FXR2 fragile X mental retardation, autosomal homolog 2
GAS8 growth arrest-specific 8
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GPER1 G protein-coupled estrogen receptor 1
HABP4 hyaluronan binding protein 4
HCRP1 hepatocellular carcinoma-related HCRP1
HDAC5 histone deacetylase 5
HLX H2.0-like homeobox
IGF1R insulin-like growth factor 1 receptor
IMPACT impact RWD domain protein
KDM4A lysine (K)-specific demethylase 4A
KIF5C kinesin family member 5C
KRIT1 KRIT1, ankyrin repeat containing
MBD4 methyl-CpG binding domain protein 4
METTL3 methyltransferase like 3
MYLK myosin light chain kinase
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NF1 neurofibromin 1
NTSR1 neurotensin receptor 1 (high affinity)
OASL 2'-5'-oligoadenylate synthetase-like
PAK1IP1 PAK1 interacting protein 1
PGAP3 post-GPI attachment to proteins 3
PHKG2 phosphorylase kinase, gamma 2 (testis)
PILRB paired immunoglobin-like type 2 receptor beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNPLA4 patatin-like phospholipase domain containing 4
POM121 POM121 transmembrane nucleoporin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
QTRT1 queuine tRNA-ribosyltransferase 1
RBM19 RNA binding motif protein 19
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFX7 regulatory factor X, 7
RPS17P5 ribosomal protein S17 pseudogene 5
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RXRA retinoid X receptor, alpha
SAFB2 scaffold attachment factor B2
SAMD4A sterile alpha motif domain containing 4A
SCAF4 SR-related CTD-associated factor 4
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SGSH N-sulfoglucosamine sulfohydrolase
SIN3B SIN3 transcription regulator family member B
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC46A3 solute carrier family 46, member 3
SMG5 SMG5 nonsense mediated mRNA decay factor
SPN sialophorin
SPPL2B signal peptide peptidase like 2B
STK16 serine/threonine kinase 16
SYNJ2 synaptojanin 2
SYNRG synergin, gamma
TBC1D13 TBC1 domain family, member 13
TMEM183A transmembrane protein 183A
TMEM97 transmembrane protein 97
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIM62 tripartite motif containing 62
TTC38 tetratricopeptide repeat domain 38
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UNC93B1 unc-93 homolog B1 (C. elegans)
WT1 Wilms tumor 1
ZBTB7A zinc finger and BTB domain containing 7A
ZNF219 zinc finger protein 219
ZNF267 zinc finger protein 267

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTG2 actin, gamma 2, smooth muscle, enteric
AGO4 argonaute RISC catalytic component 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA10 annexin A10
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARL14 ADP-ribosylation factor-like 14
ARMC6 armadillo repeat containing 6
BTF3P12 basic transcription factor 3 pseudogene 12
BTNL3 butyrophilin-like 3
C17ORF80 chromosome 17 open reading frame 80
C1R complement component 1, r subcomponent
C4BPA complement component 4 binding protein, alpha
CA5BP1 carbonic anhydrase VB pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNT1 cyclin T1
CFAP69 cilia and flagella associated protein 69
CHM choroideremia (Rab escort protein 1)
CUZD1 CUB and zona pellucida-like domains 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DOLPP1 dolichyldiphosphatase 1
DUSP2 dual specificity phosphatase 2
EML4 echinoderm microtubule associated protein like 4
EPHA4 EPH receptor A4
EXOSC5 exosome component 5
FBRS fibrosin
FER fer (fps/fes related) tyrosine kinase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GID4 GID complex subunit 4
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR176 G protein-coupled receptor 176
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HCG4 HLA complex group 4 (non-protein coding)
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IFI30 interferon, gamma-inducible protein 30
IL6 interleukin 6
INF2 inverted formin, FH2 and WH2 domain containing
IRAK4 interleukin-1 receptor-associated kinase 4
KCTD20 potassium channel tetramerization domain containing 20
KDM7A lysine (K)-specific demethylase 7A
LMO7 LIM domain 7
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MANBA mannosidase, beta A, lysosomal
MAP2 microtubule-associated protein 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP9 matrix metallopeptidase 9
MORN1 MORN repeat containing 1
MTERF4 mitochondrial transcription termination factor 4
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NOL12 nucleolar protein 12
NSUN6 NOP2/Sun domain family, member 6
NUP62CL nucleoporin 62kDa C-terminal like
NYNRIN NYN domain and retroviral integrase containing
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PADI2 peptidyl arginine deiminase, type II
PCDHA9 protocadherin alpha 9
PGPEP1 pyroglutamyl-peptidase I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRPH peripherin
PTCD2 pentatricopeptide repeat domain 2
RAB4B RAB4B, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL13P5 ribosomal protein L13 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCIN scinderin
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD1A SET domain containing 1A
SH3BGR SH3 domain binding glutamate-rich protein
SIX1 SIX homeobox 1
SLC25A40 solute carrier family 25, member 40
SLC35F6 solute carrier family 35, member F6
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNORA21 small nucleolar RNA, H/ACA box 21
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRIM25 tripartite motif containing 25
TSPAN1 tetraspanin 1
TST thiosulfate sulfurtransferase (rhodanese)
USP36 ubiquitin specific peptidase 36
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
YY2 YY2 transcription factor
ZBTB38 zinc finger and BTB domain containing 38
ZC2HC1C zinc finger, C2HC-type containing 1C
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF197 zinc finger protein 197
ZNF408 zinc finger protein 408