SB-202190-6887 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the SB-202190-6887 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM22 ADAM metallopeptidase domain 22
ADRBK2 adrenergic, beta, receptor kinase 2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BICD1 bicaudal D homolog 1 (Drosophila)
BIRC7 baculoviral IAP repeat containing 7
C11ORF80 chromosome 11 open reading frame 80
CADM1 cell adhesion molecule 1
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CDC25C cell division cycle 25C
CDK20 cyclin-dependent kinase 20
CEP162 centrosomal protein 162kDa
CNOT8 CCR4-NOT transcription complex, subunit 8
DCAF15 DDB1 and CUL4 associated factor 15
DFNB31 deafness, autosomal recessive 31
DGKQ diacylglycerol kinase, theta 110kDa
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOCK6 dedicator of cytokinesis 6
DUSP6 dual specificity phosphatase 6
ECE1 endothelin converting enzyme 1
EFNA3 ephrin-A3
EMX1 empty spiracles homeobox 1
EPOR erythropoietin receptor
FBLN1 fibulin 1
FRK fyn-related Src family tyrosine kinase
GAMT guanidinoacetate N-methyltransferase
HIST1H2AJ histone cluster 1, H2aj
HSPG2 heparan sulfate proteoglycan 2
IGFBP6 insulin-like growth factor binding protein 6
IRF2BP1 interferon regulatory factor 2 binding protein 1
LHX1 LIM homeobox 1
LIMK1 LIM domain kinase 1
LMF1 lipase maturation factor 1
LTB4R leukotriene B4 receptor
LYPD1 LY6/PLAUR domain containing 1
MAP1B microtubule-associated protein 1B
MAPK11 mitogen-activated protein kinase 11
MAPK7 mitogen-activated protein kinase 7
MAST2 microtubule associated serine/threonine kinase 2
MATK megakaryocyte-associated tyrosine kinase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MEF2C myocyte enhancer factor 2C
MPPE1 metallophosphoesterase 1
MRPS12 mitochondrial ribosomal protein S12
NAAA N-acylethanolamine acid amidase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NKX3-1 NK3 homeobox 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OGFR opioid growth factor receptor
OSBPL10 oxysterol binding protein-like 10
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PARPBP PARP1 binding protein
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX5 paired box 5
PCDHB13 protocadherin beta 13
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLIN2 perilipin 2
PML promyelocytic leukemia
PPARA peroxisome proliferator-activated receptor alpha
PRKCE protein kinase C, epsilon
RAB27B RAB27B, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RARG retinoic acid receptor, gamma
RNASEH2B ribonuclease H2, subunit B
RNF19B ring finger protein 19B
ROM1 retinal outer segment membrane protein 1
RPL18 ribosomal protein L18
RUFY3 RUN and FYVE domain containing 3
RUNDC3A RUN domain containing 3A
SIK2 salt-inducible kinase 2
SIRT3 sirtuin 3
SIX1 SIX homeobox 1
SLC22A14 solute carrier family 22, member 14
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STARD3 StAR-related lipid transfer (START) domain containing 3
SUGP1 SURP and G patch domain containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCTN2 tectonic family member 2
TMCO3 transmembrane and coiled-coil domains 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TP63 tumor protein p63
TRAF2 TNF receptor-associated factor 2
TRIM2 tripartite motif containing 2
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
USP48 ubiquitin specific peptidase 48
YY1 YY1 transcription factor
ZFPL1 zinc finger protein-like 1
ZNF506 zinc finger protein 506
ZNF79 zinc finger protein 79
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADAP2 ArfGAP with dual PH domains 2
AKR1C3 aldo-keto reductase family 1, member C3
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BBS7 Bardet-Biedl syndrome 7
C19ORF73 chromosome 19 open reading frame 73
C5ORF45 chromosome 5 open reading frame 45
C9ORF9 chromosome 9 open reading frame 9
CCDC69 coiled-coil domain containing 69
CCDC7 coiled-coil domain containing 7
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CLEC4E C-type lectin domain family 4, member E
CLSPN claspin
CRYBB2P1 crystallin, beta B2 pseudogene 1
DBF4B DBF4 zinc finger B
DENND4A DENN/MADD domain containing 4A
DGAT1 diacylglycerol O-acyltransferase 1
DTX2 deltex 2, E3 ubiquitin ligase
DUSP13 dual specificity phosphatase 13
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM179B family with sequence similarity 179, member B
FBXO22 F-box protein 22
FMO4 flavin containing monooxygenase 4
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRTP1 growth hormone regulated TBC protein 1
GTPBP2 GTP binding protein 2
H2AFY2 H2A histone family, member Y2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H1D histone cluster 1, H1d
HIST1H2AL histone cluster 1, H2al
HIST1H4D histone cluster 1, H4d
IDI2-AS1 IDI2 antisense RNA 1
IFT140 intraflagellar transport 140
KCNK15 potassium channel, two pore domain subfamily K, member 15
LIG4 ligase IV, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LINS lines homolog (Drosophila)
LOC100287590 uncharacterized LOC100287590
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGEH1 melanoma antigen family H1
MCOLN1 mucolipin 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPL52 mitochondrial ribosomal protein L52
MTCP1 mature T-cell proliferation 1
NCSTN nicastrin
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUAK1 NUAK family, SNF1-like kinase, 1
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OGFRL1 opioid growth factor receptor-like 1
OLFML2A olfactomedin-like 2A
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PGBD5 piggyBac transposable element derived 5
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G10 phospholipase A2, group X
PTK6 protein tyrosine kinase 6
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB33B RAB33B, member RAS oncogene family
RGS19 regulator of G-protein signaling 19
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
RNF43 ring finger protein 43
RPH3AL rabphilin 3A-like (without C2 domains)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SND1-IT1 SND1 intronic transcript 1
SULT4A1 sulfotransferase family 4A, member 1
SYCP2 synaptonemal complex protein 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TRAIP TRAF interacting protein
TXLNG taxilin gamma
VASH2 vasohibin 2
VLDLR very low density lipoprotein receptor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZNF211 zinc finger protein 211
ZNF516 zinc finger protein 516
ZNF557 zinc finger protein 557
ZNF571 zinc finger protein 571
ZNF747 zinc finger protein 747