S Phase Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The cell cycle phase, following G1, during which DNA synthesis takes place. (Gene Ontology, GO_0051320)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-69242
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Genes

124 proteins participating in the S Phase pathway from the Reactome Pathways dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
CCNA1 cyclin A1
CCNA2 cyclin A2
CCND1 cyclin D1
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNH cyclin H
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDCA5 cell division cycle associated 5
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDT1 chromatin licensing and DNA replication factor 1
CKS1B CDC28 protein kinase regulatory subunit 1B
CUL1 cullin 1
DNA2 DNA replication helicase/nuclease 2
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
FEN1 flap structure-specific endonuclease 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GINS4 GINS complex subunit 4 (Sld5 homolog)
LIG1 ligase I, DNA, ATP-dependent
MAX MYC associated factor X
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MCM8 minichromosome maintenance complex component 8
MNAT1 MNAT CDK-activating kinase assembly factor 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
ORC1 origin recognition complex, subunit 1
ORC2 origin recognition complex, subunit 2
ORC3 origin recognition complex, subunit 3
ORC4 origin recognition complex, subunit 4
ORC5 origin recognition complex, subunit 5
ORC6 origin recognition complex, subunit 6
PCNA proliferating cell nuclear antigen
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RAD21 RAD21 homolog (S. pombe)
RB1 retinoblastoma 1
RFC1 replication factor C (activator 1) 1, 145kDa
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RPS27A ribosomal protein S27a
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
STAG1 stromal antigen 1
STAG2 stromal antigen 2
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
WAPAL wings apart-like homolog (Drosophila)
WEE1 WEE1 G2 checkpoint kinase