Rotavirus infection of children_Peripheral blood mononuclear cell_GSE2729 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2729
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Genes

600 genes differentially expressed during Rotavirus infection of children_Peripheral blood mononuclear cell_GSE2729 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ALOX12B arachidonate 12-lipoxygenase, 12R type 3.42458
BCL2 B-cell CLL/lymphoma 2 3.12743
NSG1 neuron specific gene family member 1 3.02942
MMP15 matrix metallopeptidase 15 (membrane-inserted) 3.02854
KATNB1 katanin p80 (WD repeat containing) subunit B 1 2.99033
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 2.98086
MEF2BNB-MEF2B MEF2BNB-MEF2B readthrough 2.94392
PCDH1 protocadherin 1 2.8592
CIB2 calcium and integrin binding family member 2 2.85519
ERBB4 erb-b2 receptor tyrosine kinase 4 2.84091
PTPRN protein tyrosine phosphatase, receptor type, N 2.68555
ADAM10 ADAM metallopeptidase domain 10 2.64228
CHPF chondroitin polymerizing factor 2.62309
PAX8 paired box 8 2.60148
RAB27A RAB27A, member RAS oncogene family 2.56831
SIKE1 suppressor of IKBKE 1 2.53524
ATG4A autophagy related 4A, cysteine peptidase 2.49508
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.47146
SOCS3 suppressor of cytokine signaling 3 2.45579
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.45543
PGC progastricsin (pepsinogen C) 2.42735
HLA-A major histocompatibility complex, class I, A 2.41168
IER2 immediate early response 2 2.40731
NGFR nerve growth factor receptor 2.40101
LTC4S leukotriene C4 synthase 2.39694
RB1 retinoblastoma 1 2.38655
KIAA1024 KIAA1024 2.38631
IRS2 insulin receptor substrate 2 2.37981
NR3C2 nuclear receptor subfamily 3, group C, member 2 2.31469
ALPL alkaline phosphatase, liver/bone/kidney 2.30353
AMPD1 adenosine monophosphate deaminase 1 2.29723
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.293
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.28703
CD160 CD160 molecule 2.28646
FETUB fetuin B 2.25886
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.25356
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.24895
LLGL1 lethal giant larvae homolog 1 (Drosophila) 2.24811
ERBB2 erb-b2 receptor tyrosine kinase 2 2.24056
ALPI alkaline phosphatase, intestinal 2.23918
CLDN4 claudin 4 2.23681
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 2.23563
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 2.23059
SEC24D SEC24 family member D 2.22993
TFRC transferrin receptor 2.22826
KIAA0195 KIAA0195 2.22561
STARD5 StAR-related lipid transfer (START) domain containing 5 2.22402
ITGAV integrin, alpha V 2.21681
LYZL6 lysozyme-like 6 2.21353
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.20703
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 2.18908
TEAD3 TEA domain family member 3 2.18008
RBMY1E RNA binding motif protein, Y-linked, family 1, member E 2.17328
DBN1 drebrin 1 2.16887
PSMC3IP PSMC3 interacting protein 2.16738
NMB neuromedin B 2.1654
SSTR2 somatostatin receptor 2 2.16017
CLCNKA chloride channel, voltage-sensitive Ka 2.15235
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 2.15235
SLC35B1 solute carrier family 35, member B1 2.14485
PITPNA phosphatidylinositol transfer protein, alpha 2.14456
TRAIP TRAF interacting protein 2.13614
HIC1 hypermethylated in cancer 1 2.13519
ADAR adenosine deaminase, RNA-specific 2.13373
TSPAN5 tetraspanin 5 2.1249
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.11672
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.11553
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 2.10935
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.10019
ADGRB2 adhesion G protein-coupled receptor B2 2.09259
DNAH8 dynein, axonemal, heavy chain 8 2.08871
HSPA2 heat shock 70kDa protein 2 2.08253
REG1B regenerating islet-derived 1 beta 2.07989
SOX1 SRY (sex determining region Y)-box 1 2.06844
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.06632
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.06592
NOVA2 neuro-oncological ventral antigen 2 2.05912
FANCA Fanconi anemia, complementation group A 2.05047
S100A3 S100 calcium binding protein A3 2.04188
FAM107A family with sequence similarity 107, member A 2.03289
NOP14 NOP14 nucleolar protein 2.02036
TUBB4A tubulin, beta 4A class IVa 2.02027
PRELP proline/arginine-rich end leucine-rich repeat protein 2.01807
MTFR1 mitochondrial fission regulator 1 2.01104
PPP1R37 protein phosphatase 1, regulatory subunit 37 2.0067
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 2.00409
E2F2 E2F transcription factor 2 1.99886
ACAT2 acetyl-CoA acetyltransferase 2 1.98965
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.98005
FOXG1 forkhead box G1 1.9795
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.97484
BAK1 BCL2-antagonist/killer 1 1.97216
APOE apolipoprotein E 1.971
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.96368
FOXC2 forkhead box C2 1.95989
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.95538
MT3 metallothionein 3 1.95426
RAB36 RAB36, member RAS oncogene family 1.94866
QPRT quinolinate phosphoribosyltransferase 1.94581
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 1.94221
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.93785
C5ORF45 chromosome 5 open reading frame 45 1.936
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.93386
HPN hepsin 1.9313
DHCR24 24-dehydrocholesterol reductase 1.9311
MPZL1 myelin protein zero-like 1 1.9299
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.91453
LIPE lipase, hormone-sensitive 1.91349
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 1.8962
TIMP3 TIMP metallopeptidase inhibitor 3 1.89444
PCBP4 poly(rC) binding protein 4 1.89076
PLCD1 phospholipase C, delta 1 1.88748
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 1.86276
FANCG Fanconi anemia, complementation group G 1.8602
FANCI Fanconi anemia, complementation group I 1.85738
HES1 hes family bHLH transcription factor 1 1.85593
APOC2 apolipoprotein C-II 1.84346
CDT1 chromatin licensing and DNA replication factor 1 1.83781
H1F0 H1 histone family, member 0 1.83713
HMGA2 high mobility group AT-hook 2 1.83621
BFSP1 beaded filament structural protein 1, filensin 1.83116
FZD9 frizzled class receptor 9 1.82849
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.8256
RGS12 regulator of G-protein signaling 12 1.82482
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.82305
CTRB2 chymotrypsinogen B2 1.82104
LTBP2 latent transforming growth factor beta binding protein 2 1.81731
ARHGAP35 Rho GTPase activating protein 35 1.81695
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.81648
CRX cone-rod homeobox 1.81436
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.80972
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 1.80866
MAU2 MAU2 sister chromatid cohesion factor 1.8019
MKI67 marker of proliferation Ki-67 1.79607
ATN1 atrophin 1 1.79514
LDHC lactate dehydrogenase C 1.78345
HIST1H3D histone cluster 1, H3d 1.77493
DRG1 developmentally regulated GTP binding protein 1 1.77427
BCAP29 B-cell receptor-associated protein 29 1.77326
LOC646934 golgin A6 family, member D pseudogene 1.76932
PXN paxillin 1.76495
IFITM1 interferon induced transmembrane protein 1 1.76386
SCCPDH saccharopine dehydrogenase (putative) 1.762
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.76077
SEC61G Sec61 gamma subunit 1.75733
GFRA3 GDNF family receptor alpha 3 1.75012
IFI27 interferon, alpha-inducible protein 27 1.74934
GDE1 glycerophosphodiester phosphodiesterase 1 1.74755
BTBD3 BTB (POZ) domain containing 3 1.74567
PCDHA9 protocadherin alpha 9 1.72404
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 1.72025
LINC00302 long intergenic non-protein coding RNA 302 1.72021
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 1.71458
SCFD1 sec1 family domain containing 1 1.71405
TREH trehalase (brush-border membrane glycoprotein) 1.71292
BRD4 bromodomain containing 4 1.70867
TESK2 testis-specific kinase 2 1.69799
POU3F1 POU class 3 homeobox 1 1.6945
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 1.69444
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 1.69376
PMS2P1 postmeiotic segregation increased 2 pseudogene 1 1.69043
ST7 suppression of tumorigenicity 7 1.68976
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 1.68934
ACSBG1 acyl-CoA synthetase bubblegum family member 1 1.68931
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.68773
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.67934
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 1.6787
HOXB5 homeobox B5 1.67772
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 1.67529
PDK3 pyruvate dehydrogenase kinase, isozyme 3 1.6745
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.66944
MPHOSPH8 M-phase phosphoprotein 8 1.66743
GRIP1 glutamate receptor interacting protein 1 1.66131
CALU calumenin 1.65826
NR2C2 nuclear receptor subfamily 2, group C, member 2 1.65617
BCAM basal cell adhesion molecule (Lutheran blood group) 1.6532
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.65275
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 1.65248
PC pyruvate carboxylase 1.65065
ADRA1A adrenoceptor alpha 1A 1.64975
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.64891
ANG angiogenin, ribonuclease, RNase A family, 5 1.64578
KRT5 keratin 5, type II 1.63824
TRIM15 tripartite motif containing 15 1.6328
PCBP3 poly(rC) binding protein 3 1.63227
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 1.63218
LDLR low density lipoprotein receptor 1.62783
PYCR1 pyrroline-5-carboxylate reductase 1 1.61619
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.61616
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 1.61058
LIPC lipase, hepatic 1.60928
PAPPA pregnancy-associated plasma protein A, pappalysin 1 1.6064
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.60416
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.60152
HPS1 Hermansky-Pudlak syndrome 1 1.60121
SIGLEC6 sialic acid binding Ig-like lectin 6 1.59785
PKP1 plakophilin 1 1.5952
RLBP1 retinaldehyde binding protein 1 1.58794
FOLR1 folate receptor 1 (adult) 1.5846
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 1.58311
CCIN calicin 1.58193
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 1.57641
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 1.57576
KRT13 keratin 13, type I 1.57394
IGF1R insulin-like growth factor 1 receptor 1.57226
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.5694
TSSK2 testis-specific serine kinase 2 1.56937
TERT telomerase reverse transcriptase 1.56795
PTPRS protein tyrosine phosphatase, receptor type, S 1.56069
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 1.55788
FSCN2 fascin actin-bundling protein 2, retinal 1.55735
COX7B cytochrome c oxidase subunit VIIb 1.55694
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 1.55572
SPINK5 serine peptidase inhibitor, Kazal type 5 1.55418
GJC2 gap junction protein, gamma 2, 47kDa 1.55285
ACVR2A activin A receptor, type IIA 1.54428
RHCE Rh blood group, CcEe antigens 1.54376
AQP6 aquaporin 6, kidney specific 1.54139
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 1.53837
PRDM1 PR domain containing 1, with ZNF domain 1.53548
AREG amphiregulin 1.53354
GPR12 G protein-coupled receptor 12 1.53339
TSPAN1 tetraspanin 1 1.53116
ASB4 ankyrin repeat and SOCS box containing 4 1.53088
ARL1 ADP-ribosylation factor-like 1 1.52516
SDC1 syndecan 1 1.5223
ITSN1 intersectin 1 (SH3 domain protein) 1.51984
CD47 CD47 molecule 1.51491
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 1.51252
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.51145
GPR6 G protein-coupled receptor 6 1.50964
NCOA6 nuclear receptor coactivator 6 1.50699
TERF2 telomeric repeat binding factor 2 1.50631
ZNF674 zinc finger protein 674 1.50367
RND1 Rho family GTPase 1 1.50327
ZNF205 zinc finger protein 205 1.50068
KLF11 Kruppel-like factor 11 1.50002
JTB jumping translocation breakpoint 1.49949
PRB4 proline-rich protein BstNI subfamily 4 1.4954
CFLAR CASP8 and FADD-like apoptosis regulator 1.49468
CNGB1 cyclic nucleotide gated channel beta 1 1.49465
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 1.49141
C1QB complement component 1, q subcomponent, B chain 1.48774
TBX2 T-box 2 1.48702
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 1.48556
COMP cartilage oligomeric matrix protein 1.4845
FOXK2 forkhead box K2 1.48405
HIST1H1E histone cluster 1, H1e 1.47962
MFSD5 major facilitator superfamily domain containing 5 1.47714
FAS Fas cell surface death receptor 1.47588
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 1.47366
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 1.46968
NGF nerve growth factor (beta polypeptide) 1.46593
NCAPH2 non-SMC condensin II complex, subunit H2 1.46394
RBM15B RNA binding motif protein 15B 1.46301
OR7E12P olfactory receptor, family 7, subfamily E, member 12 pseudogene 1.46078
IGKV1OR2-118 immunoglobulin kappa variable 1/OR2-118 (pseudogene) 1.45435
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.45067
HOXB1 homeobox B1 1.44796
PIAS4 protein inhibitor of activated STAT, 4 1.44391
SAMD14 sterile alpha motif domain containing 14 1.44229
MAPKAPK5-AS1 MAPKAPK5 antisense RNA 1 1.43753
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.43723
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 1.43624
SPAG8 sperm associated antigen 8 1.43546
CLDN3 claudin 3 1.43477
ADGRE2 adhesion G protein-coupled receptor E2 1.43363
OSR2 odd-skipped related transciption factor 2 1.4324
ZMPSTE24 zinc metallopeptidase STE24 1.43055
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 1.42942
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.42905
SEPT11 septin 11 1.42746
BRCA1 breast cancer 1, early onset 1.42732
CD80 CD80 molecule 1.42422
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 1.424
NAT6 N-acetyltransferase 6 (GCN5-related) 1.42371
GSK3B glycogen synthase kinase 3 beta 1.41601
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.41539
SREBF2 sterol regulatory element binding transcription factor 2 1.41378
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 1.41351
SCAMP5 secretory carrier membrane protein 5 1.41231
PLTP phospholipid transfer protein 1.40792
DOCK4 dedicator of cytokinesis 4 1.40489
FBN2 fibrillin 2 1.40483
GUK1 guanylate kinase 1 1.40276
FBP2 fructose-1,6-bisphosphatase 2 1.40123
ASCC3 activating signal cointegrator 1 complex subunit 3 1.40047
NR6A1 nuclear receptor subfamily 6, group A, member 1 1.40008
ZNF141 zinc finger protein 141 1.39979
DOC2B double C2-like domains, beta 1.39869
HNF4A hepatocyte nuclear factor 4, alpha 1.39634
CDK18 cyclin-dependent kinase 18 1.39622
MRC2 mannose receptor, C type 2 1.39153
ANKRD40 ankyrin repeat domain 40 1.38423
CSPG4 chondroitin sulfate proteoglycan 4 1.38369
ADORA1 adenosine A1 receptor 1.3833
EXO1 exonuclease 1 1.38282
ALOX5 arachidonate 5-lipoxygenase 1.38218
FKBP6 FK506 binding protein 6, 36kDa 1.38143
WBSCR22 Williams Beuren syndrome chromosome region 22 1.37654

decreased expression

Symbol Name Standardized Value
GRB7 growth factor receptor-bound protein 7 -3.37801
CDK13 cyclin-dependent kinase 13 -2.94139
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -2.907
ACVR1 activin A receptor, type I -2.90396
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 -2.80449
ZNF623 zinc finger protein 623 -2.79862
MED22 mediator complex subunit 22 -2.78876
ANKRD46 ankyrin repeat domain 46 -2.73362
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 -2.72984
PPT2 palmitoyl-protein thioesterase 2 -2.68366
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -2.62857
SRCAP Snf2-related CREBBP activator protein -2.61412
ACO1 aconitase 1, soluble -2.5924
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 -2.56875
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -2.56228
ENOX2 ecto-NOX disulfide-thiol exchanger 2 -2.5549
FAM32A family with sequence similarity 32, member A -2.5406
GPR50 G protein-coupled receptor 50 -2.52214
CCNO cyclin O -2.51476
MPPED1 metallophosphoesterase domain containing 1 -2.51108
UMPS uridine monophosphate synthetase -2.49557
TUBA4A tubulin, alpha 4a -2.4847
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 -2.47979
HARS2 histidyl-tRNA synthetase 2, mitochondrial -2.47378
ZNF23 zinc finger protein 23 -2.47366
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.46292
KIAA0907 KIAA0907 -2.46157
CDH16 cadherin 16, KSP-cadherin -2.45944
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -2.43481
SRSF7 serine/arginine-rich splicing factor 7 -2.43049
BBS9 Bardet-Biedl syndrome 9 -2.41616
RAB22A RAB22A, member RAS oncogene family -2.41611
RPL27A ribosomal protein L27a -2.41605
DDR1 discoidin domain receptor tyrosine kinase 1 -2.40918
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G -2.38538
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 -2.38058
MAEA macrophage erythroblast attacher -2.37779
BRD8 bromodomain containing 8 -2.35834
EFNA3 ephrin-A3 -2.34137
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -2.3323
KANK3 KN motif and ankyrin repeat domains 3 -2.32853
SENP5 SUMO1/sentrin specific peptidase 5 -2.31003
AIP aryl hydrocarbon receptor interacting protein -2.30856
CETN1 centrin, EF-hand protein, 1 -2.2963
DBP D site of albumin promoter (albumin D-box) binding protein -2.294
LRP5 low density lipoprotein receptor-related protein 5 -2.29185
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -2.25651
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) -2.25644
CLN5 ceroid-lipofuscinosis, neuronal 5 -2.25486
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.24841
SSTR5 somatostatin receptor 5 -2.24778
SLC46A3 solute carrier family 46, member 3 -2.24405
MED7 mediator complex subunit 7 -2.24018
FADD Fas (TNFRSF6)-associated via death domain -2.23656
ZC3H14 zinc finger CCCH-type containing 14 -2.22357
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -2.2233
NAIP NLR family, apoptosis inhibitory protein -2.20894
RPS8 ribosomal protein S8 -2.19241
ZNF140 zinc finger protein 140 -2.1809
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.17988
CCNG2 cyclin G2 -2.16868
EXD2 exonuclease 3'-5' domain containing 2 -2.15138
RPL4 ribosomal protein L4 -2.146
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 -2.145
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -2.13199
PLCB2 phospholipase C, beta 2 -2.12635
WDR1 WD repeat domain 1 -2.12196
INTS9 integrator complex subunit 9 -2.10722
MAP2K4 mitogen-activated protein kinase kinase 4 -2.10422
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 -2.09604
CP ceruloplasmin (ferroxidase) -2.09545
PISD phosphatidylserine decarboxylase -2.08273
TPM2 tropomyosin 2 (beta) -2.06842
NUP160 nucleoporin 160kDa -2.05175
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -2.05134
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.03863
NUP214 nucleoporin 214kDa -2.03419
MKL1 megakaryoblastic leukemia (translocation) 1 -2.03113
MEST mesoderm specific transcript -2.01965
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -2.01448
S100B S100 calcium binding protein B -2.00889
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -2.00626
CCKBR cholecystokinin B receptor -1.99926
ERI3 ERI1 exoribonuclease family member 3 -1.98993
HOXB7 homeobox B7 -1.98676
FAM178A family with sequence similarity 178, member A -1.98021
PRODH2 proline dehydrogenase (oxidase) 2 -1.97864
HUS1 HUS1 checkpoint homolog (S. pombe) -1.97193
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.97176
PMPCB peptidase (mitochondrial processing) beta -1.96133
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 -1.95874
MRFAP1L1 Morf4 family associated protein 1-like 1 -1.95864
NUP133 nucleoporin 133kDa -1.95135
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -1.95027
AZU1 azurocidin 1 -1.94782
MRS2 MRS2 magnesium transporter -1.94556
OPN1SW opsin 1 (cone pigments), short-wave-sensitive -1.94197
HBBP1 hemoglobin, beta pseudogene 1 -1.94162
UBE3B ubiquitin protein ligase E3B -1.94147
GNA12 guanine nucleotide binding protein (G protein) alpha 12 -1.93822
NPPA natriuretic peptide A -1.93812
LUC7L3 LUC7-like 3 (S. cerevisiae) -1.9336
MFAP1 microfibrillar-associated protein 1 -1.91933
PPP1R26 protein phosphatase 1, regulatory subunit 26 -1.91037
SLK STE20-like kinase -1.90942
ZNF217 zinc finger protein 217 -1.89418
C12ORF29 chromosome 12 open reading frame 29 -1.8899
SOD3 superoxide dismutase 3, extracellular -1.88869
IL16 interleukin 16 -1.88319
KPNA6 karyopherin alpha 6 (importin alpha 7) -1.88238
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding) -1.88193
FEM1B fem-1 homolog b (C. elegans) -1.871
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -1.867
IFT140 intraflagellar transport 140 -1.86255
ZNF84 zinc finger protein 84 -1.85937
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 -1.85798
RAB35 RAB35, member RAS oncogene family -1.8573
MANBA mannosidase, beta A, lysosomal -1.85589
NIPAL3 NIPA-like domain containing 3 -1.8556
EIF3F eukaryotic translation initiation factor 3, subunit F -1.8483
CLUAP1 clusterin associated protein 1 -1.84825
PHEX phosphate regulating endopeptidase homolog, X-linked -1.8386
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -1.83451
LAMB2 laminin, beta 2 (laminin S) -1.83249
PNISR PNN-interacting serine/arginine-rich protein -1.82863
SELENBP1 selenium binding protein 1 -1.82712
PEX3 peroxisomal biogenesis factor 3 -1.82288
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -1.81935
IPO7 importin 7 -1.80251
UTF1 undifferentiated embryonic cell transcription factor 1 -1.80233
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 -1.79986
MAK16 MAK16 homolog (S. cerevisiae) -1.79884
DHRS1 dehydrogenase/reductase (SDR family) member 1 -1.79874
PRUNE prune exopolyphosphatase -1.79856
CAPN5 calpain 5 -1.78533
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit -1.78317
ZNF184 zinc finger protein 184 -1.77559
CTR9 CTR9, Paf1/RNA polymerase II complex component -1.77123
FADS1 fatty acid desaturase 1 -1.76892
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -1.76872
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -1.76656
ERC1 ELKS/RAB6-interacting/CAST family member 1 -1.76643
CD40LG CD40 ligand -1.76546
RBM5 RNA binding motif protein 5 -1.76396
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -1.75654
MYH7 myosin, heavy chain 7, cardiac muscle, beta -1.75328
RGS10 regulator of G-protein signaling 10 -1.74564
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -1.74546
ZNF292 zinc finger protein 292 -1.74449
MYO16 myosin XVI -1.74443
RPL5 ribosomal protein L5 -1.74016
UBE2I ubiquitin-conjugating enzyme E2I -1.73934
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -1.73927
SLC7A4 solute carrier family 7, member 4 -1.73915
PKP3 plakophilin 3 -1.73643
PQBP1 polyglutamine binding protein 1 -1.73321
ANKRD6 ankyrin repeat domain 6 -1.72043
MVK mevalonate kinase -1.71487
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -1.71458
TEAD4 TEA domain family member 4 -1.71365
TRAF1 TNF receptor-associated factor 1 -1.71271
MAP2K5 mitogen-activated protein kinase kinase 5 -1.71222
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -1.70988
RPS10 ribosomal protein S10 -1.70958
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 -1.70719
TFR2 transferrin receptor 2 -1.70498
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -1.70453
TBL1X transducin (beta)-like 1X-linked -1.7013
SEC62 SEC62 homolog (S. cerevisiae) -1.69222
CR2 complement component (3d/Epstein Barr virus) receptor 2 -1.69189
SOX21 SRY (sex determining region Y)-box 21 -1.69145
CXCL13 chemokine (C-X-C motif) ligand 13 -1.6908
ZNF354A zinc finger protein 354A -1.68917
USP15 ubiquitin specific peptidase 15 -1.68518
CLPS colipase, pancreatic -1.68351
PURA purine-rich element binding protein A -1.67675
RHBDD3 rhomboid domain containing 3 -1.6716
PTH parathyroid hormone -1.66579
TRAF5 TNF receptor-associated factor 5 -1.66479
TULP1 tubby like protein 1 -1.66224
LOR loricrin -1.65931
MFAP3 microfibrillar-associated protein 3 -1.65594
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -1.65562
PVR poliovirus receptor -1.65311
THAP3 THAP domain containing, apoptosis associated protein 3 -1.65296
NARS asparaginyl-tRNA synthetase -1.65216
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -1.64255
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -1.64182
ZBTB24 zinc finger and BTB domain containing 24 -1.63559
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled -1.63456
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -1.62399
RUVBL1 RuvB-like AAA ATPase 1 -1.61627
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -1.60999
CYTH2 cytohesin 2 -1.60802
HMX1 H6 family homeobox 1 -1.60763
ZNF646 zinc finger protein 646 -1.60333
CBR4 carbonyl reductase 4 -1.59931
FCHO1 FCH domain only 1 -1.59489
RXRG retinoid X receptor, gamma -1.59456
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.59087
DPY19L4 dpy-19-like 4 (C. elegans) -1.58468
TK2 thymidine kinase 2, mitochondrial -1.58455
CLN3 ceroid-lipofuscinosis, neuronal 3 -1.58361
CPB2 carboxypeptidase B2 (plasma) -1.58222
ZNF467 zinc finger protein 467 -1.58128
RBM8A RNA binding motif protein 8A -1.5738
CACTIN cactin, spliceosome C complex subunit -1.57328
RPS3 ribosomal protein S3 -1.5727
CYB5R3 cytochrome b5 reductase 3 -1.57189
EIF3D eukaryotic translation initiation factor 3, subunit D -1.57162
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.57158
PREPL prolyl endopeptidase-like -1.56951
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa -1.56849
NCBP1 nuclear cap binding protein subunit 1, 80kDa -1.56642
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -1.56258
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 -1.56256
TP53 tumor protein p53 -1.56135
ELP4 elongator acetyltransferase complex subunit 4 -1.56081
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 -1.55607
ODF2 outer dense fiber of sperm tails 2 -1.5524
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -1.54603
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa -1.54577
GRAP2 GRB2-related adaptor protein 2 -1.54535
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -1.54468
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -1.54351
HEXA hexosaminidase A (alpha polypeptide) -1.54267
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -1.5374
PITX3 paired-like homeodomain 3 -1.53618
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -1.53582
MEF2C myocyte enhancer factor 2C -1.53483
CHMP7 charged multivesicular body protein 7 -1.53433
ESRRA estrogen-related receptor alpha -1.5326
KRT76 keratin 76, type II -1.52742
TCEAL1 transcription elongation factor A (SII)-like 1 -1.52279
APLNR apelin receptor -1.52151
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -1.5206
CD48 CD48 molecule -1.51916
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -1.51866
ERV9-1 endogenous retrovirus group 9, member 1 -1.51765
RNF24 ring finger protein 24 -1.51105
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -1.51078
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 -1.51056
OLIG2 oligodendrocyte lineage transcription factor 2 -1.51006
KLC1 kinesin light chain 1 -1.50942
ASF1A anti-silencing function 1A histone chaperone -1.50815
ELF4 E74-like factor 4 (ets domain transcription factor) -1.50534
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) -1.50386
ARHGAP32 Rho GTPase activating protein 32 -1.4999
BIN1 bridging integrator 1 -1.49981
EED embryonic ectoderm development -1.49717
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -1.49682
TRIM32 tripartite motif containing 32 -1.49576
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 -1.49548
LEPROTL1 leptin receptor overlapping transcript-like 1 -1.49322
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -1.49275
TAGLN transgelin -1.49241
MEOX1 mesenchyme homeobox 1 -1.49133
KIF1B kinesin family member 1B -1.49076
GLS glutaminase -1.489
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.48853
RPL18 ribosomal protein L18 -1.48433
ARMC8 armadillo repeat containing 8 -1.48213
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -1.48185
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 -1.48173
IVNS1ABP influenza virus NS1A binding protein -1.48125
ADRA2A adrenoceptor alpha 2A -1.4804
ZNF175 zinc finger protein 175 -1.47938
SIK3 SIK family kinase 3 -1.47816
RPLP2 ribosomal protein, large, P2 -1.47722
ACOX3 acyl-CoA oxidase 3, pristanoyl -1.47409
SYPL1 synaptophysin-like 1 -1.47352
FMO4 flavin containing monooxygenase 4 -1.47336
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -1.47296
LPA lipoprotein, Lp(a) -1.47241
TULP2 tubby like protein 2 -1.47226
TBC1D4 TBC1 domain family, member 4 -1.47213
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -1.47118
ASB1 ankyrin repeat and SOCS box containing 1 -1.46895
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -1.4677
ADAM23 ADAM metallopeptidase domain 23 -1.46747
SF3B3 splicing factor 3b, subunit 3, 130kDa -1.46601
SACS sacsin molecular chaperone -1.46571
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -1.4613
PKI55 DKFZp434H1419 -1.46104
RPL38 ribosomal protein L38 -1.45969
VAV1 vav 1 guanine nucleotide exchange factor -1.45965
RPS17 ribosomal protein S17 -1.45823
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -1.45686
MFAP2 microfibrillar-associated protein 2 -1.455
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -1.45154
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -1.44599
CDH4 cadherin 4, type 1, R-cadherin (retinal) -1.44475
IZUMO4 IZUMO family member 4 -1.44294
SFTPC surfactant protein C -1.44227
ACAA1 acetyl-CoA acyltransferase 1 -1.44102
ASXL1 additional sex combs like transcriptional regulator 1 -1.44067
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -1.43991
ADSL adenylosuccinate lyase -1.438
DLG4 discs, large homolog 4 (Drosophila) -1.43525
CFHR3 complement factor H-related 3 -1.43337