Rheumatoid arthritis Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint. (Human Disease Ontology, DOID_7148)
External Link https://www.ebi.ac.uk/gwas/search?query=Rheumatoid arthritis
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Genes

77 genes associated with the Rheumatoid arthritis phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
C6ORF10 chromosome 6 open reading frame 10 2.78643
PHTF1 putative homeodomain transcription factor 1 1.4482
CCR6 chemokine (C-C motif) receptor 6 1.34627
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.177
ANKRD55 ankyrin repeat domain 55 1.12476
ARID5B AT rich interactive domain 5B (MRF1-like) 1.10105
DPP4 dipeptidyl-peptidase 4 1.08247
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.02384
STAT4 signal transducer and activator of transcription 4 1.00206
PADI4 peptidyl arginine deiminase, type IV 0.987567
LINC01104 long intergenic non-protein coding RNA 1104 0.976249
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.976249
CD40 CD40 molecule, TNF receptor superfamily member 5 0.964741
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.958097
MICA MHC class I polypeptide-related sequence A 0.950225
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.910257
SYNGR1 synaptogyrin 1 0.910257
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.881997
MECP2 methyl CpG binding protein 2 0.877381
TYK2 tyrosine kinase 2 0.877381
SPRED2 sprouty-related, EVH1 domain containing 2 0.841354
IL2RA interleukin 2 receptor, alpha 0.831366
PLD4 phospholipase D family, member 4 0.802698
TRAF1 TNF receptor-associated factor 1 0.786836
LOC100506023 uncharacterized LOC100506023 0.721487
ANXA3 annexin A3 0.713153
MTF1 metal-regulatory transcription factor 1 0.686534
UBASH3A ubiquitin associated and SH3 domain containing A 0.66525
C5ORF30 chromosome 5 open reading frame 30 0.637972
TNPO3 transportin 3 0.618573
PHF19 PHD finger protein 19 0.612268
PLCL2 phospholipase C-like 2 0.612268
RAD51B RAD51 paralog B 0.598838
SUOX sulfite oxidase 0.592545
LOC399716 uncharacterized LOC399716 0.560615
LOC101929761 0.552116
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.539238
ATG5 autophagy related 5 0.530146
CD226 CD226 molecule 0.526478
STAG1 stromal antigen 1 0.526478
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.499091
ALS2CR12 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 0.499091
PRKCH protein kinase C, eta 0.499091
JAZF1 JAZF zinc finger 1 0.483518
GATA3 GATA binding protein 3 0.483518
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 0.483518
WDFY4 WDFY family member 4 0.483518
AIRE autoimmune regulator 0.472799
IL6R interleukin 6 receptor 0.472799
CDK6 cyclin-dependent kinase 6 0.463473
RTKN2 rhotekin 2 0.463473
GATSL3 GATS protein-like 3 0.449549
ACOXL acyl-CoA oxidase-like 0.439318
SFTPD surfactant protein D 0.439318
EOMES eomesodermin 0.439318
FADS2 fatty acid desaturase 2 0.405958
TEC tec protein tyrosine kinase 0.389385
FAM107A family with sequence similarity 107, member A 0.369252
RPP14 ribonuclease P/MRP 14kDa subunit 0.369252
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.356403
KIF5A kinesin family member 5A 0.346786
MMEL1 membrane metallo-endopeptidase-like 1 0.342586
IRF5 interferon regulatory factor 5 0.295129
KIAA1109 KIAA1109 0.246511
GCH1 GTP cyclohydrolase 1 0.165905
CD247 CD247 molecule 0.165905
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.165905
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.165905
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 0.129504
GMCL1P1 germ cell-less, spermatogenesis associated 1 pseudogene 1 0.104568
PRKCB protein kinase C, beta 0.104568
BLK BLK proto-oncogene, Src family tyrosine kinase 0.085234
SH2B3 SH2B adaptor protein 3 0.070053
TRHDE thyrotropin-releasing hormone degrading enzyme 0.070053
IL2RB interleukin 2 receptor, beta 0.070053
ARL15 ADP-ribosylation factor-like 15 0.057619
ANAPC4 anaphase promoting complex subunit 4 0.042592