Retinoblastoma Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A retinal cell cancer and malignant neoplasm of retina and neuroblastoma and neuroendocrine tumors that derives_from the tissues of the retina. (Human Disease Ontology, DOID_768)
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Genes

16 genes associated with the Retinoblastoma phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DHFR dihydrofolate reductase
DRD4 dopamine receptor D4
KRAS Kirsten rat sarcoma viral oncogene homolog
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
RFC1 replication factor C (activator 1) 1, 145kDa
TP53 tumor protein p53
TYMS thymidylate synthetase