Retinal Diseases Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D012164
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Genes

209 genes/proteins associated with the disease Retinal Diseases from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNF tumor necrosis factor 2.88009
PDGFB platelet-derived growth factor beta polypeptide 2.88009
IFNA2 interferon, alpha 2 2.88009
COL9A1 collagen, type IX, alpha 1 2.88009
THY1 Thy-1 cell surface antigen 2.88009
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 2.88009
ICAM1 intercellular adhesion molecule 1 2.88009
VEGFA vascular endothelial growth factor A 2.88009
SIRT1 sirtuin 1 2.88009
VSX1 visual system homeobox 1 2.88009
MTNR1A melatonin receptor 1A 2.88009
PTPRC protein tyrosine phosphatase, receptor type, C 2.88009
PKD2 polycystic kidney disease 2 (autosomal dominant) 2.88009
HMOX1 heme oxygenase 1 2.88009
OCLN occludin 2.88009
FZD4 frizzled class receptor 4 2.88009
MMP9 matrix metallopeptidase 9 2.88009
NOS2 nitric oxide synthase 2, inducible 2.88009
CHAT choline O-acetyltransferase 2.88009
SDCCAG8 serologically defined colon cancer antigen 8 2.88009
VIM vimentin 2.88009
TTPA tocopherol (alpha) transfer protein 2.88009
IL6 interleukin 6 1.97655
CAT catalase 1.93169
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.89488
IL1B interleukin 1, beta 1.78987
PRL prolactin 1.76849
BCL2 B-cell CLL/lymphoma 2 1.75023
BAX BCL2-associated X protein 1.73938
FAS Fas cell surface death receptor 1.72509
DDIT3 DNA-damage-inducible transcript 3 1.69721
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.68846
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.67912
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.63294
BCL2L1 BCL2-like 1 1.6287
DUSP1 dual specificity phosphatase 1 1.6249
SOD2 superoxide dismutase 2, mitochondrial 1.59381
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.58113
BDNF brain-derived neurotrophic factor 1.5641
EGR1 early growth response 1 1.55698
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.52938
CCL2 chemokine (C-C motif) ligand 2 1.52743
CXCL8 chemokine (C-X-C motif) ligand 8 1.52136
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.51607
MAPK8 mitogen-activated protein kinase 8 1.49122
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.47889
TGFB1 transforming growth factor, beta 1 1.47322
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.47167
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.46807
NGF nerve growth factor (beta polypeptide) 1.46542
SOD1 superoxide dismutase 1, soluble 1.45352
EDN1 endothelin 1 1.44872
IL10 interleukin 10 1.44599
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.44084
JUN jun proto-oncogene 1.43809
PARP1 poly (ADP-ribose) polymerase 1 1.42156
NOS3 nitric oxide synthase 3 (endothelial cell) 1.41667
IL4 interleukin 4 1.41478
MAPK1 mitogen-activated protein kinase 1 1.40316
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.39757
IFNG interferon, gamma 1.39338
DRD2 dopamine receptor D2 1.38298
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.381
EDNRA endothelin receptor type A 1.381
TP53 tumor protein p53 1.37874
MAPK14 mitogen-activated protein kinase 14 1.37332
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.37075
CALR calreticulin 1.37047
IL1A interleukin 1, alpha 1.35962
CRH corticotropin releasing hormone 1.34053
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.33791
CCND3 cyclin D3 1.33464
EDNRB endothelin receptor type B 1.32726
GAP43 growth associated protein 43 1.32637
DRD1 dopamine receptor D1 1.32339
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.3231
MAOA monoamine oxidase A 1.32162
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.31897
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.30512
TH tyrosine hydroxylase 1.30299
HSPA1A heat shock 70kDa protein 1A 1.30147
GSR glutathione reductase 1.30087
FOXO1 forkhead box O1 1.29812
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.2898
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.28796
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.28518
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.28487
CTSD cathepsin D 1.28487
SQSTM1 sequestosome 1 1.28303
FOS FBJ murine osteosarcoma viral oncogene homolog 1.27657
CYCS cytochrome c, somatic 1.27626
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.27009
FOXO3 forkhead box O3 1.26298
NOS1 nitric oxide synthase 1 (neuronal) 1.26205
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.25432
GSTP1 glutathione S-transferase pi 1 1.25152
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.25152
IL2 interleukin 2 1.25121
MAPK3 mitogen-activated protein kinase 3 1.24997
SYP synaptophysin 1.24687
IGF1 insulin-like growth factor 1 (somatomedin C) 1.2368
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.22566
GSK3B glycogen synthase kinase 3 beta 1.22566
LEP leptin 1.22242
BAD BCL2-associated agonist of cell death 1.2208
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.21919
SPP1 secreted phosphoprotein 1 1.21695
NPPA natriuretic peptide A 1.21239
PLCG1 phospholipase C, gamma 1 1.20816
TFRC transferrin receptor 1.20687
ALOX12 arachidonate 12-lipoxygenase 1.19279
S100B S100 calcium binding protein B 1.19179
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.18882
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.18816
MMP13 matrix metallopeptidase 13 1.18456
F3 coagulation factor III (thromboplastin, tissue factor) 1.18259
COL1A1 collagen, type I, alpha 1 1.18126
XBP1 X-box binding protein 1 1.18093
VCAM1 vascular cell adhesion molecule 1 1.17926
CXCL10 chemokine (C-X-C motif) ligand 10 1.17662
LCN2 lipocalin 2 1.17563
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.17399
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.17101
NEFH neurofilament, heavy polypeptide 1.16368
CCNA2 cyclin A2 1.1617
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.1617
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.16137
BECN1 beclin 1, autophagy related 1.16137
MMP3 matrix metallopeptidase 3 1.15899
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.15391
CCND1 cyclin D1 1.14885
ATF3 activating transcription factor 3 1.14507
FN1 fibronectin 1 1.14507
GFAP glial fibrillary acidic protein 1.14268
PLAU plasminogen activator, urokinase 1.14268
PGK1 phosphoglycerate kinase 1 1.1403
IDI1 isopentenyl-diphosphate delta isomerase 1 1.13793
MBP myelin basic protein 1.13793
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.13347
CTSL cathepsin L 1.12906
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.12906
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.12703
CCL5 chemokine (C-C motif) ligand 5 1.12117
PRKCA protein kinase C, alpha 1.11707
MAP2K1 mitogen-activated protein kinase kinase 1 1.10838
EGFR epidermal growth factor receptor 1.10282
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.10211
CXCL2 chemokine (C-X-C motif) ligand 2 1.10175
MMP2 matrix metallopeptidase 2 1.10104
JUNB jun B proto-oncogene 1.09998
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.09716
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.09646
RAD51 RAD51 recombinase 1.09576
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.09401
PPARG peroxisome proliferator-activated receptor gamma 1.09297
BIRC5 baculoviral IAP repeat containing 5 1.09226
EPO erythropoietin 1.0919
TLR4 toll-like receptor 4 1.09154
CYBA cytochrome b-245, alpha polypeptide 1.08797
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.0869
CLU clusterin 1.08619
FASLG Fas ligand (TNF superfamily, member 6) 1.08337
GADD45A growth arrest and DNA-damage-inducible, alpha 1.08301
GLRB glycine receptor, beta 1.08055
TXN thioredoxin 1.0766
FAM107A family with sequence similarity 107, member A 1.07411
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.07376
IRS1 insulin receptor substrate 1 1.07305
GAL galanin/GMAP prepropeptide 1.07093
FBXO32 F-box protein 32 1.07093
ARC activity-regulated cytoskeleton-associated protein 1.06515
FYN FYN proto-oncogene, Src family tyrosine kinase 1.06225
NPY neuropeptide Y 1.06188
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.05721
CD68 CD68 molecule 1.05685
HSPB1 heat shock 27kDa protein 1 1.0561
NDRG1 N-myc downstream regulated 1 1.05498
GDNF glial cell derived neurotrophic factor 1.05126
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.04941
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.04904
CLDN1 claudin 1 1.04611
CXCR4 chemokine (C-X-C motif) receptor 4 1.04611
EFHD1 EF-hand domain family, member D1 1.04465
PHGDH phosphoglycerate dehydrogenase 1.04352
GRN granulin 1.04352
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.04088
GCLC glutamate-cysteine ligase, catalytic subunit 1.03939
IGFBP1 insulin-like growth factor binding protein 1 1.03901
CCL3 chemokine (C-C motif) ligand 3 1.03752
BTG2 BTG family, member 2 1.03752
ATF4 activating transcription factor 4 1.03567
FABP3 fatty acid binding protein 3, muscle and heart 1.03308
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.03308
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.03271
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.03197
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.03159
ACO2 aconitase 2, mitochondrial 1.03084
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.03046
TF transferrin 1.02896
ADRA1B adrenoceptor alpha 1B 1.02821
TPI1 triosephosphate isomerase 1 1.02783
CD44 CD44 molecule (Indian blood group) 1.02746
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 1.02336
GSK3A glycogen synthase kinase 3 alpha 1.02299
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.01625
NFE2L2 nuclear factor, erythroid 2-like 2 1.01399
MPO myeloperoxidase 1.01174
PRKCD protein kinase C, delta 1.01137
KLF4 Kruppel-like factor 4 (gut) 1.01099