Respiratory Insufficiency Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide. (Human Phenotype Ontology, HP_0002093)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D012131
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Genes

593 genes/proteins associated with the disease Respiratory Insufficiency from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
PLAT plasminogen activator, tissue 2.88009
FBLN5 fibulin 5 2.88009
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 2.88009
PDYN prodynorphin 2.88009
TRH thyrotropin-releasing hormone 2.88009
MECP2 methyl CpG binding protein 2 2.88009
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 2.88009
MAPT microtubule-associated protein tau 2.88009
IFT80 intraflagellar transport 80 2.88009
IGF1R insulin-like growth factor 1 receptor 2.88009
MGME1 mitochondrial genome maintenance exonuclease 1 2.88009
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.40481
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.32903
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.27043
FOS FBJ murine osteosarcoma viral oncogene homolog 2.26145
TNF tumor necrosis factor 2.25418
BAX BCL2-associated X protein 2.19145
POMC proopiomelanocortin 2.18341
IL1B interleukin 1, beta 2.14995
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.13305
MAPK1 mitogen-activated protein kinase 1 2.11753
IL6 interleukin 6 2.11341
JUN jun proto-oncogene 2.10486
MAPK3 mitogen-activated protein kinase 3 2.09522
OPRK1 opioid receptor, kappa 1 2.05954
BCL2 B-cell CLL/lymphoma 2 2.04098
OPRM1 opioid receptor, mu 1 2.00481
REN renin 1.99867
CAT catalase 1.99719
CXCL8 chemokine (C-X-C motif) ligand 8 1.9831
EGR1 early growth response 1 1.96847
CREB1 cAMP responsive element binding protein 1 1.96447
CRH corticotropin releasing hormone 1.96117
CCL2 chemokine (C-C motif) ligand 2 1.94595
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.93368
NOS2 nitric oxide synthase 2, inducible 1.8996
PRL prolactin 1.88753
NPY neuropeptide Y 1.88209
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.87592
ODC1 ornithine decarboxylase 1 1.8648
FAS Fas cell surface death receptor 1.85869
BDNF brain-derived neurotrophic factor 1.8559
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.82551
S100A9 S100 calcium binding protein A9 1.80265
OPRD1 opioid receptor, delta 1 1.79579
IL1A interleukin 1, alpha 1.7956
IFNG interferon, gamma 1.78911
PENK proenkephalin 1.77801
ICAM1 intercellular adhesion molecule 1 1.77743
HMOX1 heme oxygenase 1 1.77374
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.76111
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.74923
IL4 interleukin 4 1.74381
IL10 interleukin 10 1.73008
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.72717
TP53 tumor protein p53 1.72219
MPO myeloperoxidase 1.71296
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.70553
PER1 period circadian clock 1 1.69972
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.6934
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.68062
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.66641
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.66576
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.66188
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.65511
TGFB1 transforming growth factor, beta 1 1.65445
INHBE inhibin, beta E 1.64708
AVP arginine vasopressin 1.64595
LPL lipoprotein lipase 1.64123
NUPR1 nuclear protein, transcriptional regulator, 1 1.64078
CES2 carboxylesterase 2 1.63272
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.63027
CYCS cytochrome c, somatic 1.6229
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.61759
CCL3 chemokine (C-C motif) ligand 3 1.61667
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.61506
ALB albumin 1.61224
G6PD glucose-6-phosphate dehydrogenase 1.60874
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.60711
SOD2 superoxide dismutase 2, mitochondrial 1.59661
IL2 interleukin 2 1.59148
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.58514
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.58491
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.58303
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.58232
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.57853
DUSP1 dual specificity phosphatase 1 1.57522
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.57114
EDNRB endothelin receptor type B 1.56971
COMT catechol-O-methyltransferase 1.56386
MAOA monoamine oxidase A 1.56288
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.55921
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.55427
GSK3B glycogen synthase kinase 3 beta 1.54766
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.54475
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.54354
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.53868
JUNB jun B proto-oncogene 1.53283
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.52439
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.52111
S100A8 S100 calcium binding protein A8 1.52086
NPPA natriuretic peptide A 1.51531
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.51481
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.51456
ATF3 activating transcription factor 3 1.51456
COL1A1 collagen, type I, alpha 1 1.492
VCAM1 vascular cell adhesion molecule 1 1.48941
VEGFA vascular endothelial growth factor A 1.4794
TEX261 testis expressed 261 1.47556
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.47219
TAGLN transgelin 1.47115
CNR1 cannabinoid receptor 1 (brain) 1.46436
TAT tyrosine aminotransferase 1.46409
NGF nerve growth factor (beta polypeptide) 1.45617
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.45247
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.44763
DRD2 dopamine receptor D2 1.44111
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.437
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.4351
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.42967
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.42616
PRKCE protein kinase C, epsilon 1.42589
ADRA1B adrenoceptor alpha 1B 1.42401
SREBF1 sterol regulatory element binding transcription factor 1 1.41721
ADRB1 adrenoceptor beta 1 1.41341
DDIT3 DNA-damage-inducible transcript 3 1.41229
ADRA2B adrenoceptor alpha 2B 1.41119
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.41008
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.4087
MMP9 matrix metallopeptidase 9 1.40842
INS insulin 1.40732
GFAP glial fibrillary acidic protein 1.40732
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.40705
GPX1 glutathione peroxidase 1 1.40457
CREM cAMP responsive element modulator 1.40232
FOXO1 forkhead box O1 1.39924
TH tyrosine hydroxylase 1.39226
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.3878
LHB luteinizing hormone beta polypeptide 1.38242
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.38156
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.381
LZTFL1 leucine zipper transcription factor-like 1 1.37987
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.37987
ACHE acetylcholinesterase (Yt blood group) 1.37987
GCLC glutamate-cysteine ligase, catalytic subunit 1.37958
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.36591
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.36447
PGD phosphogluconate dehydrogenase 1.36447
GNAS GNAS complex locus 1.36447
SGK1 serum/glucocorticoid regulated kinase 1 1.36418
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.36133
F3 coagulation factor III (thromboplastin, tissue factor) 1.35962
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1.35618
TRAF2 TNF receptor-associated factor 2 1.35155
BTG2 BTG family, member 2 1.34869
CDC25A cell division cycle 25A 1.34635
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.34285
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 1.34227
C10ORF10 chromosome 10 open reading frame 10 1.34227
IGF1 insulin-like growth factor 1 (somatomedin C) 1.34111
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.33761
GJB1 gap junction protein, beta 1, 32kDa 1.33287
FASLG Fas ligand (TNF superfamily, member 6) 1.3311
BCHE butyrylcholinesterase 1.32964
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.32935
CCND1 cyclin D1 1.32846
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.32846
MCL1 myeloid cell leukemia 1 1.32607
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.32607
BCL2L1 BCL2-like 1 1.32103
GAMT guanidinoacetate N-methyltransferase 1.31985
HTRA1 HtrA serine peptidase 1 1.31985
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.31956
PKM pyruvate kinase, muscle 1.31956
PRKCD protein kinase C, delta 1.31536
APAF1 apoptotic peptidase activating factor 1 1.31446
CCL5 chemokine (C-C motif) ligand 5 1.31148
KRT18 keratin 18, type I 1.30941
CYBB cytochrome b-245, beta polypeptide 1.30696
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.30421
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.30269
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.30056
APP amyloid beta (A4) precursor protein 1.29966
FABP1 fatty acid binding protein 1, liver 1.29966
NOS1 nitric oxide synthase 1 (neuronal) 1.29936
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.29471
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.2944
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.29133
PYGL phosphorylase, glycogen, liver 1.29041
RRM2 ribonucleotide reductase M2 1.29011
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.28919
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.28641
MAPK8 mitogen-activated protein kinase 8 1.28549
ALDOA aldolase A, fructose-bisphosphate 1.28518
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.28487
TIMP1 TIMP metallopeptidase inhibitor 1 1.2821
RORA RAR-related orphan receptor A 1.27845
CALCA calcitonin-related polypeptide alpha 1.27626
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.27471
RND3 Rho family GTPase 3 1.27471
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.27347
TGFB2 transforming growth factor, beta 2 1.27347
DRD1 dopamine receptor D1 1.27132
LBP lipopolysaccharide binding protein 1.2707
CCNA2 cyclin A2 1.27039
ACSL6 acyl-CoA synthetase long-chain family member 6 1.26732
OTC ornithine carbamoyltransferase 1.26732
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.26732
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 1.267
GADD45A growth arrest and DNA-damage-inducible, alpha 1.26236
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.26205
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.26021
MMP13 matrix metallopeptidase 13 1.25807
UBC ubiquitin C 1.25588
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.25307
DNASE1 deoxyribonuclease I 1.25307
SNTG2 syntrophin, gamma 2 1.25307
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 1.25276
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.25214
TUBB tubulin, beta class I 1.25214
NBN nibrin 1.25183
CTSL cathepsin L 1.2509
H2AFX H2A histone family, member X 1.24905
CTSB cathepsin B 1.24718
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.24528
TLR4 toll-like receptor 4 1.2437
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.24307
PHYH phytanoyl-CoA 2-hydroxylase 1.24213
PDLIM7 PDZ and LIM domain 7 (enigma) 1.24181
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.2415
ADORA1 adenosine A1 receptor 1.24024
EGR2 early growth response 2 1.24024
CPT1A carnitine palmitoyltransferase 1A (liver) 1.23868
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.23806
CLU clusterin 1.2368
SOD1 superoxide dismutase 1, soluble 1.23648
ADRB3 adrenoceptor beta 3 1.23456
MME membrane metallo-endopeptidase 1.23456
CCK cholecystokinin 1.23456
CD14 CD14 molecule 1.23424
FMO2 flavin containing monooxygenase 2 (non-functional) 1.23233
CALD1 caldesmon 1 1.23233
CD44 CD44 molecule (Indian blood group) 1.23233
DTX4 deltex 4, E3 ubiquitin ligase 1.23074
DDIT4 DNA-damage-inducible transcript 4 1.23011
FOSL2 FOS-like antigen 2 1.2279
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.22758
TUBA4A tubulin, alpha 4a 1.22758
EGFR epidermal growth factor receptor 1.22534
ZMYND8 zinc finger, MYND-type containing 8 1.22371
MMP2 matrix metallopeptidase 2 1.22306
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.22177
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.2208
LDHB lactate dehydrogenase B 1.2208
CCKBR cholecystokinin B receptor 1.21823
CLEC2D C-type lectin domain family 2, member D 1.21695
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.21663
PER2 period circadian clock 2 1.21435
SRM spermidine synthase 1.2137
CP ceruloplasmin (ferroxidase) 1.21173
MARCKS myristoylated alanine-rich protein kinase C substrate 1.21108
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.21011
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.20913
CA2 carbonic anhydrase II 1.20913
PRKCB protein kinase C, beta 1.20913
BAG3 BCL2-associated athanogene 3 1.20784
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.20654
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.20654
IL13 interleukin 13 1.20558
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 1.20526
JAK1 Janus kinase 1 1.2046
UBE2I ubiquitin-conjugating enzyme E2I 1.2046
GSR glutathione reductase 1.20394
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.20361
CPN1 carboxypeptidase N, polypeptide 1 1.20361
MAP7 microtubule-associated protein 7 1.20361
TAC1 tachykinin, precursor 1 1.19966
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.19933
HSPB1 heat shock 27kDa protein 1 1.19802
ACO2 aconitase 2, mitochondrial 1.19802
LEP leptin 1.1977
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 1.19704
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.19574
AVPR1A arginine vasopressin receptor 1A 1.19574
POR P450 (cytochrome) oxidoreductase 1.19312
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.19146
SPP1 secreted phosphoprotein 1 1.1908
TSPO translocator protein (18kDa) 1.18849
ADRB2 adrenoceptor beta 2, surface 1.18816
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.18751
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.18751
CD47 CD47 molecule 1.18718
GCK glucokinase (hexokinase 4) 1.18554
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.18456
NTSR1 neurotensin receptor 1 (high affinity) 1.18456
MAG myelin associated glycoprotein 1.18456
CCL4 chemokine (C-C motif) ligand 4 1.18424
HOMER1 homer scaffolding protein 1 1.18326
CFLAR CASP8 and FADD-like apoptosis regulator 1.18226
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.17893
AK4 adenylate kinase 4 1.17893
EDN1 endothelin 1 1.17794
KRT8 keratin 8, type II 1.17761
PDE4B phosphodiesterase 4B, cAMP-specific 1.17629
NEFH neurofilament, heavy polypeptide 1.17629
ANXA1 annexin A1 1.1753
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.17497
RTN4 reticulon 4 1.17497
RBL1 retinoblastoma-like 1 1.17497
BHLHE40 basic helix-loop-helix family, member e40 1.17333
TSC22D3 TSC22 domain family, member 3 1.17067
COL3A1 collagen, type III, alpha 1 1.16866
LIN7C lin-7 homolog C (C. elegans) 1.16533
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.16104
SLCO3A1 solute carrier organic anion transporter family, member 3A1 1.16104
PARP1 poly (ADP-ribose) polymerase 1 1.16001
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.15967
VNN1 vanin 1 1.15899
CIRBP cold inducible RNA binding protein 1.15899
MSMO1 methylsterol monooxygenase 1 1.15899
HSPA8 heat shock 70kDa protein 8 1.15661
CTGF connective tissue growth factor 1.15492
PPARA peroxisome proliferator-activated receptor alpha 1.15458
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.15324
FN1 fibronectin 1 1.15189
MAPK14 mitogen-activated protein kinase 14 1.15022
BMF Bcl2 modifying factor 1.14989
CCNB1 cyclin B1 1.14781
NT5E 5'-nucleotidase, ecto (CD73) 1.14747
SUMF1 sulfatase modifying factor 1 1.14713
TTR transthyretin 1.1461
FMO1 flavin containing monooxygenase 1 1.14473
MBP myelin basic protein 1.14473
INHBA inhibin, beta A 1.14473
ASL argininosuccinate lyase 1.14438
OPRL1 opiate receptor-like 1 1.14438
CCND2 cyclin D2 1.14404
XBP1 X-box binding protein 1 1.14404
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.142
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.14166
ACSS2 acyl-CoA synthetase short-chain family member 2 1.13895
TRHR thyrotropin-releasing hormone receptor 1.13862
HPCA hippocalcin 1.13862
ST5 suppression of tumorigenicity 5 1.13827
GJA1 gap junction protein, alpha 1, 43kDa 1.13724
FKBP5 FK506 binding protein 5 1.13655
LEPR leptin receptor 1.13552
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.13347
POU2F1 POU class 2 homeobox 1 1.13347
RGS4 regulator of G-protein signaling 4 1.13279
ERRFI1 ERBB receptor feedback inhibitor 1 1.13279
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.13279
FGF2 fibroblast growth factor 2 (basic) 1.13211
FAM132A family with sequence similarity 132, member A 1.13177
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.13109
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.13109
VWF von Willebrand factor 1.12906
GRK5 G protein-coupled receptor kinase 5 1.12838
HPN hepsin 1.12838
C3 complement component 3 1.12703
TFRC transferrin receptor 1.12703
GAST gastrin 1.12564
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.12564
SERINC3 serine incorporator 3 1.12323
GAL galanin/GMAP prepropeptide 1.12219
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.12219
UGCG UDP-glucose ceramide glucosyltransferase 1.12185
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.12048
KLF6 Kruppel-like factor 6 1.12048
S100A10 S100 calcium binding protein A10 1.11843
LAMB1 laminin, beta 1 1.11843
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.11843
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.11501
ARC activity-regulated cytoskeleton-associated protein 1.11501
PCF11 PCF11 cleavage and polyadenylation factor subunit 1.11431
PRODH proline dehydrogenase (oxidase) 1 1.1136
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 1.1136
SHMT1 serine hydroxymethyltransferase 1 (soluble) 1.11325
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 1.11325
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.11255
RXRG retinoid X receptor, gamma 1.11151
LGALS3 lectin, galactoside-binding, soluble, 3 1.11011
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.10872
TP53INP1 tumor protein p53 inducible nuclear protein 1 1.10838
DCXR dicarbonyl/L-xylulose reductase 1.10838
PDIA6 protein disulfide isomerase family A, member 6 1.10838
MT1X metallothionein 1X 1.10838
PLLP plasmolipin 1.10665
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 1.10665
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.10665
SIVA1 SIVA1, apoptosis-inducing factor 1.10665
ALDOC aldolase C, fructose-bisphosphate 1.10493
ADRA2A adrenoceptor alpha 2A 1.10493
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.10493
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.10493
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.10388
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.10388
PVALB parvalbumin 1.10388
GAS1 growth arrest-specific 1 1.10388
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.10353
CALR calreticulin 1.10246
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.10246
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.10069
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.09998
INADL InaD-like (Drosophila) 1.09927
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.09436
MAOB monoamine oxidase B 1.09262
SLC14A2 solute carrier family 14 (urea transporter), member 2 1.0919
RGS8 regulator of G-protein signaling 8 1.0919
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 1.0919
DOCK9 dedicator of cytokinesis 9 1.0919
TLCD1 TLC domain containing 1 1.0919
CLDN1 claudin 1 1.09154
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.09011
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 1.08975
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.08975
PLSCR1 phospholipid scramblase 1 1.08975
MCM4 minichromosome maintenance complex component 4 1.08513
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.08513
USP2 ubiquitin specific peptidase 2 1.08513
ANXA2 annexin A2 1.08513
BBC3 BCL2 binding component 3 1.08513
MT1A metallothionein 1A 1.08337
ADM adrenomedullin 1.08301
CCNE1 cyclin E1 1.08301
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.08196
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.08196
DPP4 dipeptidyl-peptidase 4 1.07875
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.07875
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 1.07768
PLXNB2 plexin B2 1.07768
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.07625
NINJ1 ninjurin 1 1.07625
AOC1 amine oxidase, copper containing 1 1.07625
AHCY adenosylhomocysteinase 1.07625
LMCD1 LIM and cysteine-rich domains 1 1.07625
FAT1 FAT atypical cadherin 1 1.07625
TMEM97 transmembrane protein 97 1.07625
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.07589
MCM5 minichromosome maintenance complex component 5 1.07553
FST follistatin 1.07553
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.07269
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.07269
KYNU kynureninase 1.07199
ACTG2 actin, gamma 2, smooth muscle, enteric 1.07163
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.07093
MAP2K2 mitogen-activated protein kinase kinase 2 1.07093
FAM46C family with sequence similarity 46, member C 1.07093
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.07093
LDLR low density lipoprotein receptor 1.07022
NUCB2 nucleobindin 2 1.06734
VLDLR very low density lipoprotein receptor 1.06661
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 1.06588
U2SURP U2 snRNP-associated SURP domain containing 1.06552
SLMO2 slowmo homolog 2 (Drosophila) 1.06552
ARHGAP5 Rho GTPase activating protein 5 1.06442
TUBA8 tubulin, alpha 8 1.06442
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 1.06442
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.06442
CYR61 cysteine-rich, angiogenic inducer, 61 1.06406
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 1.06333
CPE carboxypeptidase E 1.06333
CIDEA cell death-inducing DFFA-like effector a 1.06333
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.06333
CCNG2 cyclin G2 1.06333
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.06333
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.06188
TXNIP thioredoxin interacting protein 1.06188
KLF9 Kruppel-like factor 9 1.06044
THRSP thyroid hormone responsive 1.06044
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.06044
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.059
SFTPB surfactant protein B 1.059
BACE1 beta-site APP-cleaving enzyme 1 1.059
GEM GTP binding protein overexpressed in skeletal muscle 1.059
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.059
TGM1 transglutaminase 1 1.059
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 1.05793
EFHD2 EF-hand domain family, member D2 1.05793
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.05721
CRP C-reactive protein, pentraxin-related 1.05573
FSHB follicle stimulating hormone, beta polypeptide 1.05573
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.05498
DUSP10 dual specificity phosphatase 10 1.05461
NFIA nuclear factor I/A 1.05461
CBLN1 cerebellin 1 precursor 1.05423
S100A4 S100 calcium binding protein A4 1.05423
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa 1.05386
GSTP1 glutathione S-transferase pi 1 1.05349
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.05274
RBMX RNA binding motif protein, X-linked 1.05163
WNK1 WNK lysine deficient protein kinase 1 1.05163
TUFT1 tuftelin 1 1.05163
TRA2A transformer 2 alpha homolog (Drosophila) 1.05163
TJP3 tight junction protein 3 1.05126
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.05126
HGD homogentisate 1,2-dioxygenase 1.05126
ACOT4 acyl-CoA thioesterase 4 1.05126
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.05052
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.05052
GPX3 glutathione peroxidase 3 1.05052
CHEK2 checkpoint kinase 2 1.05052
HMGB2 high mobility group box 2 1.04831
ADORA2A adenosine A2a receptor 1.04831
HES1 hes family bHLH transcription factor 1 1.04831
KLF4 Kruppel-like factor 4 (gut) 1.04831
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.04647
RELN reelin 1.04647
CALCRL calcitonin receptor-like 1.04538
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.04538
NOS3 nitric oxide synthase 3 (endothelial cell) 1.04538
IL2RA interleukin 2 receptor, alpha 1.04538
MCF2L MCF.2 cell line derived transforming sequence-like 1.04501
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.04352
EFNA2 ephrin-A2 1.04314
PNPLA2 patatin-like phospholipase domain containing 2 1.04239
ARRDC3 arrestin domain containing 3 1.04239
CDC6 cell division cycle 6 1.04239
CD36 CD36 molecule (thrombospondin receptor) 1.04126
RB1 retinoblastoma 1 1.04014
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.03939
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.03939
INA internexin neuronal intermediate filament protein, alpha 1.03901
PLP1 proteolipid protein 1 1.03901
AACS acetoacetyl-CoA synthetase 1.03901
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.03827
S100A11 S100 calcium binding protein A11 1.03827
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.03678
IFRD1 interferon-related developmental regulator 1 1.03678
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.03678
HRH1 histamine receptor H1 1.03678
CRYAB crystallin, alpha B 1.03493
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.03419
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.03419
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 1.03419
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1.03308
HNRNPR heterogeneous nuclear ribonucleoprotein R 1.03308
NCEH1 neutral cholesterol ester hydrolase 1 1.03308
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.03271
RNF152 ring finger protein 152 1.03235
NOL6 nucleolar protein 6 (RNA-associated) 1.03235
AFMID arylformamidase 1.03235
ATG4B autophagy related 4B, cysteine peptidase 1.03235
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.03122
DBP D site of albumin promoter (albumin D-box) binding protein 1.03046
CES1 carboxylesterase 1 1.03046
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.03046
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.02821
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.02708
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 1.02708
MBD1 methyl-CpG binding domain protein 1 1.02708
PLXNA2 plexin A2 1.02708
PTPN3 protein tyrosine phosphatase, non-receptor type 3 1.02708
HLF hepatic leukemia factor 1.02708
FGF21 fibroblast growth factor 21 1.02634
E2F1 E2F transcription factor 1 1.02634
CHRM1 cholinergic receptor, muscarinic 1 1.02559
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.02373
LAMC2 laminin, gamma 2 1.02262
CA14 carbonic anhydrase XIV 1.02262
PHLDA1 pleckstrin homology-like domain, family A, member 1 1.02262
EPM2AIP1 EPM2A (laforin) interacting protein 1 1.02225
IGSF3 immunoglobulin superfamily, member 3 1.02225
MRPL50 mitochondrial ribosomal protein L50 1.02225
IGFBP1 insulin-like growth factor binding protein 1 1.02188
SLC38A4 solute carrier family 38, member 4 1.02114
FUBP1 far upstream element (FUSE) binding protein 1 1.02114
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.02114
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 1.02114
SON SON DNA binding protein 1.02114
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 1.0204
NDRG2 NDRG family member 2 1.0189
CXCR2 chemokine (C-X-C motif) receptor 2 1.0189
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 1.01587
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.01587
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.01549
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.01549
HN1 hematological and neurological expressed 1 1.01549
CD52 CD52 molecule 1.01549
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.01512
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.01399
KIFC2 kinesin family member C2 1.01286
CLCC1 chloride channel CLIC-like 1 1.01249
SDSL serine dehydratase-like 1.01249
HAP1 huntingtin-associated protein 1 1.01249
SUCNR1 succinate receptor 1 1.01249
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.01249
CASP12 caspase 12 (gene/pseudogene) 1.01174
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.01174
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.01137
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.01137
UGP2 UDP-glucose pyrophosphorylase 2 1.01025
DPYSL3 dihydropyrimidinase-like 3 1.01025