Respiratory Function Tests Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc. (Experimental Factor Ontology, EFO_0003892)
Similar Terms
Downloads & Tools

Genes

151 genes associated with the trait Respiratory Function Tests in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.61884
SNX9 sorting nexin 9 1.57685
GSTCD glutathione S-transferase, C-terminal domain containing 1.50783
LIPM lipase, family member M 1.43597
PTPRD protein tyrosine phosphatase, receptor type, D 1.41138
INTS12 integrator complex subunit 12 1.28701
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.25168
MFAP2 microfibrillar-associated protein 2 1.23835
AGER advanced glycosylation end product-specific receptor 1.20587
THSD4 thrombospondin, type I, domain containing 4 1.18594
RARB retinoic acid receptor, beta 1.15135
CDC123 cell division cycle 123 1.08574
TNS1 tensin 1 1.07287
CDH13 cadherin 13 1.05611
C10ORF11 chromosome 10 open reading frame 11 1.04648
CHRM3 cholinergic receptor, muscarinic 3 1.03531
OPCML opioid binding protein/cell adhesion molecule-like 1.02994
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 1.01477
CFDP1 craniofacial development protein 1 0.995026
CCDC38 coiled-coil domain containing 38 0.995026
ADAM19 ADAM metallopeptidase domain 19 0.944178
FHIT fragile histidine triad 0.9287
MCC mutated in colorectal cancers 0.92254
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 0.922056
ZSCAN31 zinc finger and SCAN domain containing 31 0.922056
KIAA2026 KIAA2026 0.909362
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.904589
ABHD12B abhydrolase domain containing 12B 0.8714
ADGRG6 adhesion G protein-coupled receptor G6 0.862644
RCSD1 RCSD domain containing 1 0.824425
CCDC174 coiled-coil domain containing 174 0.822827
M1AP meiosis 1 associated protein 0.815815
OSBPL6 oxysterol binding protein-like 6 0.799621
ARMC2 armadillo repeat containing 2 0.774665
LRP1 low density lipoprotein receptor-related protein 1 0.763999
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.758823
CCDC91 coiled-coil domain containing 91 0.738677
FAM172A family with sequence similarity 172, member A 0.734045
GRM1 glutamate receptor, metabotropic 1 0.724977
MECOM MDS1 and EVI1 complex locus 0.711358
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.696869
LINGO2 leucine rich repeat and Ig domain containing 2 0.689489
ASB1 ankyrin repeat and SOCS box containing 1 0.667558
GLIS3 GLIS family zinc finger 3 0.66381
DAAM2 dishevelled associated activator of morphogenesis 2 0.660359
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.659151
SYT1 synaptotagmin I 0.652981
BTBD16 BTB (POZ) domain containing 16 0.652467
FAM13A family with sequence similarity 13, member A 0.64828
LRRC49 leucine rich repeat containing 49 0.64554
AGBL4 ATP/GTP binding protein-like 4 0.644438
AUH AU RNA binding protein/enoyl-CoA hydratase 0.637115
ATRNL1 attractin-like 1 0.631521
TENM3 teneurin transmembrane protein 3 0.627794
EYA2 EYA transcriptional coactivator and phosphatase 2 0.625541
LMX1A LIM homeobox transcription factor 1, alpha 0.619683
PROM1 prominin 1 0.611447
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.610036
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.609816
WWOX WW domain containing oxidoreductase 0.609816
MICB MHC class I polypeptide-related sequence B 0.609816
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 0.608395
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 0.595374
CCBL2 cysteine conjugate-beta lyase 2 0.581499
THSD7A thrombospondin, type I, domain containing 7A 0.578408
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 0.565662
DOCK4 dedicator of cytokinesis 4 0.555492
ADRA1D adrenoceptor alpha 1D 0.554528
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.552134
PTCH1 patched 1 0.552134
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 0.551586
CLCA1 chloride channel accessory 1 0.544657
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.538362
IGF1R insulin-like growth factor 1 receptor 0.536612
CLSTN2 calsyntenin 2 0.532831
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 0.52912
NRG3 neuregulin 3 0.52575
PRSS35 protease, serine, 35 0.516421
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 0.51105
ZFYVE28 zinc finger, FYVE domain containing 28 0.506135
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.49106
TENM2 teneurin transmembrane protein 2 0.47918
SNRPN small nuclear ribonucleoprotein polypeptide N 0.476265
MYO16 myosin XVI 0.475395
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.467478
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 0.455855
ITGA1 integrin, alpha 1 0.443956
ANKRD7 ankyrin repeat domain 7 0.443013
COL1A2 collagen, type I, alpha 2 0.437251
RPH3A rabphilin 3A 0.423158
ADARB1 adenosine deaminase, RNA-specific, B1 0.406869
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.405911
PDE4DIP phosphodiesterase 4D interacting protein 0.381822
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 0.378873
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase 0.378873
FBXL7 F-box and leucine-rich repeat protein 7 0.366413
SNTG1 syntrophin, gamma 1 0.356676
MOXD1 monooxygenase, DBH-like 1 0.353132
SLC44A1 solute carrier family 44 (choline transporter), member 1 0.343364
PRUNE2 prune homolog 2 (Drosophila) 0.339256
LRRC9 leucine rich repeat containing 9 0.337966
ATP10B ATPase, class V, type 10B 0.296083
SOBP sine oculis binding protein homolog (Drosophila) 0.293289
ANKRD44 ankyrin repeat domain 44 0.287637
SPATA13 spermatogenesis associated 13 0.286609
PHEX phosphate regulating endopeptidase homolog, X-linked 0.27691
KIAA1211 KIAA1211 0.267001
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 0.257471
CFAP47 cilia and flagella associated protein 47 0.246569
EFHC1 EF-hand domain (C-terminal) containing 1 0.24416
EGFR epidermal growth factor receptor 0.239786
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 0.236701
MAP10 microtubule-associated protein 10 0.234185
PAX3 paired box 3 0.220427
CADM1 cell adhesion molecule 1 0.213671
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.209926
CCDC71L coiled-coil domain containing 71-like 0.192817
ZW10 zw10 kinetochore protein 0.168566
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.161049
MAST2 microtubule associated serine/threonine kinase 2 0.15417
ANXA2P3 annexin A2 pseudogene 3 0.151107
HSF2 heat shock transcription factor 2 0.146815
XIRP2 xin actin binding repeat containing 2 0.136297
SYT9 synaptotagmin IX 0.135779
TENM4 teneurin transmembrane protein 4 0.135262
LAMA1 laminin, alpha 1 0.132686
TPO thyroid peroxidase 0.126074
PKN2 protein kinase N2 0.119989
ATXN7 ataxin 7 0.117946
GEMIN5 gem (nuclear organelle) associated protein 5 0.116421
FOCAD focadhesin 0.114398
SOX30 SRY (sex determining region Y)-box 30 0.111384
DSCAM Down syndrome cell adhesion molecule 0.110385
DFNB31 deafness, autosomal recessive 31 0.110385
NHLRC2 NHL repeat containing 2 0.103467
PBRM1 polybromo 1 0.102002
PPHLN1 periphilin 1 0.098123
PDZD2 PDZ domain containing 2 0.097641
JAM2 junctional adhesion molecule 2 0.096679
DNAH6 dynein, axonemal, heavy chain 6 0.093363
LIPF lipase, gastric 0.092482
MOB3B MOB kinase activator 3B 0.092042
ADGRL4 adhesion G protein-coupled receptor L4 0.081224
SERINC1 serine incorporator 1 0.072386
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.070727
CAST calpastatin 0.065983
DLG1 discs, large homolog 1 (Drosophila) 0.064656
CADM2 cell adhesion molecule 2 0.064325
GSTO2 glutathione S-transferase omega 2 0.062347
PTCHD1 patched domain containing 1 0.061362
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.059075