Renal Insufficiency, Chronic Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D051436
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Genes

102 genes/proteins associated with the disease Renal Insufficiency, Chronic from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
NGF nerve growth factor (beta polypeptide) 2.88009
RETN resistin 2.88009
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.4966
TNF tumor necrosis factor 1.45643
BAX BCL2-associated X protein 1.42321
CYCS cytochrome c, somatic 1.41341
VEGFA vascular endothelial growth factor A 1.39924
IL2 interleukin 2 1.39591
BCL2 B-cell CLL/lymphoma 2 1.38527
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.37733
NOS3 nitric oxide synthase 3 (endothelial cell) 1.36961
IL1B interleukin 1, beta 1.36876
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.36562
FOS FBJ murine osteosarcoma viral oncogene homolog 1.35213
IL6 interleukin 6 1.34256
SOD1 superoxide dismutase 1, soluble 1.33081
BIRC2 baculoviral IAP repeat containing 2 1.31297
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.30512
HMOX1 heme oxygenase 1 1.30269
CAT catalase 1.29936
BIRC5 baculoviral IAP repeat containing 5 1.29533
PPARG peroxisome proliferator-activated receptor gamma 1.28827
CCND2 cyclin D2 1.28734
TGFB1 transforming growth factor, beta 1 1.28364
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.27813
CD44 CD44 molecule (Indian blood group) 1.27502
JUN jun proto-oncogene 1.26021
SOD2 superoxide dismutase 2, mitochondrial 1.25276
PARP1 poly (ADP-ribose) polymerase 1 1.24935
COL18A1 collagen, type XVIII, alpha 1 1.24874
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.24118
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.22145
FASLG Fas ligand (TNF superfamily, member 6) 1.21727
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.21043
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.20229
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.19835
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.19509
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.19146
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.18489
IL10 interleukin 10 1.17761
FLT1 fms-related tyrosine kinase 1 1.17497
FN1 fibronectin 1 1.17202
TP53 tumor protein p53 1.16467
TJP1 tight junction protein 1 1.16368
NFE2L2 nuclear factor, erythroid 2-like 2 1.16137
CCL5 chemokine (C-C motif) ligand 5 1.15526
NOS2 nitric oxide synthase 2, inducible 1.15357
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.14885
ALB albumin 1.14781
GSK3B glycogen synthase kinase 3 beta 1.1461
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.14541
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 1.13177
GSK3A glycogen synthase kinase 3 alpha 1.12805
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.12668
COL1A1 collagen, type I, alpha 1 1.11606
VCAM1 vascular cell adhesion molecule 1 1.11466
KL klotho 1.11011
CCND1 cyclin D1 1.10942
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.10211
APP amyloid beta (A4) precursor protein 1.10175
PCNA proliferating cell nuclear antigen 1.10069
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.09576
FAS Fas cell surface death receptor 1.09332
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.08584
MAPK3 mitogen-activated protein kinase 3 1.08266
MPO myeloperoxidase 1.08019
MAPK1 mitogen-activated protein kinase 1 1.07589
DDIT3 DNA-damage-inducible transcript 3 1.07376
RXRA retinoid X receptor, alpha 1.07305
KDR kinase insert domain receptor 1.07269
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.07234
EGFR epidermal growth factor receptor 1.06261
CCL2 chemokine (C-C motif) ligand 2 1.06152
MMP2 matrix metallopeptidase 2 1.06152
FSHB follicle stimulating hormone, beta polypeptide 1.06044
MAP2K1 mitogen-activated protein kinase kinase 1 1.05972
CXCL8 chemokine (C-X-C motif) ligand 8 1.05757
ZEB1 zinc finger E-box binding homeobox 1 1.0561
JUNB jun B proto-oncogene 1.05312
GSR glutathione reductase 1.05163
PLAT plasminogen activator, tissue 1.05015
BAD BCL2-associated agonist of cell death 1.04941
G6PD glucose-6-phosphate dehydrogenase 1.04904
LTA lymphotoxin alpha 1.04831
TLR4 toll-like receptor 4 1.04794
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 1.04314
FGF2 fibroblast growth factor 2 (basic) 1.04276
TFRC transferrin receptor 1.03976
PECAM1 platelet/endothelial cell adhesion molecule 1 1.03567
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.03308
DUSP1 dual specificity phosphatase 1 1.03046
ATF6 activating transcription factor 6 1.02858
BCL2L1 BCL2-like 1 1.02596
CDK4 cyclin-dependent kinase 4 1.02485
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.02373
HSPA1A heat shock 70kDa protein 1A 1.02336
TGFBR1 transforming growth factor, beta receptor 1 1.02151
GSTP1 glutathione S-transferase pi 1 1.01928
LHB luteinizing hormone beta polypeptide 1.0189
S100B S100 calcium binding protein B 1.01701
ACTA2 actin, alpha 2, smooth muscle, aorta 1.01474
ICAM1 intercellular adhesion molecule 1 1.01286