Radiation Pneumonitis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

66 genes associated with the Radiation Pneumonitis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ANKRD62P1-PARP4P3 ANKRD62P1-PARP4P3 readthrough, transcribed pseudogene
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ATM ATM serine/threonine kinase
CCL2 chemokine (C-C motif) ligand 2
CENPE centromere protein E, 312kDa
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
EGFR epidermal growth factor receptor
FEN1 flap structure-specific endonuclease 1
GSTP1 glutathione S-transferase pi 1
HSPB1 heat shock 27kDa protein 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNG interferon, gamma
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL16 interleukin 16
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
LIG4 ligase IV, DNA, ATP-dependent
LIN28A lin-28 homolog A (C. elegans)
LIN28B lin-28 homolog B (C. elegans)
LTA lymphotoxin alpha
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NBN nibrin
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
OGG1 8-oxoguanine DNA glycosylase
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAD51 RAD51 recombinase
SOD2 superoxide dismutase 2, mitochondrial
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TXNRD2 thioredoxin reductase 2
VEGFA vascular endothelial growth factor A
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6