RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-168928
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Genes

79 proteins participating in the RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways pathway from the Reactome Pathways dataset.

Symbol Name
AGER advanced glycosylation end product-specific receptor
APP amyloid beta (A4) precursor protein
ATG12 autophagy related 12
ATG5 autophagy related 5
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHUK conserved helix-loop-helix ubiquitous kinase
CREBBP CREB binding protein
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EP300 E1A binding protein p300
FADD Fas (TNFRSF6)-associated via death domain
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HMGB1 high mobility group box 1
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNB1 interferon, beta 1, fibroblast
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
ISG15 ISG15 ubiquitin-like modifier
ITCH itchy E3 ubiquitin protein ligase
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAVS mitochondrial antiviral signaling protein
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLRC5 NLR family, CARD domain containing 5
NLRX1 NLR family member X1
OTUD5 OTU deubiquitinase 5
PCBP2 poly(rC) binding protein 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF135 ring finger protein 135
RPS27A ribosomal protein S27a
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SIKE1 suppressor of IKBKE 1
TANK TRAF family member-associated NFKB activator
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBK1 TANK-binding kinase 1
TKFC triokinase/FMN cyclase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM25 tripartite motif containing 25
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA7 ubiquitin-like modifier activating enzyme 7
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L6 ubiquitin-conjugating enzyme E2L 6