Pyruvate metabolism and Citric Acid (TCA) cycle Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-71406
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Genes

43 proteins participating in the Pyruvate metabolism and Citric Acid (TCA) cycle pathway from the Reactome Pathways dataset.

Symbol Name
ACO2 aconitase 2, mitochondrial
ADHFE1 alcohol dehydrogenase, iron containing, 1
BSG basigin (Ok blood group)
CS citrate synthase
D2HGDH D-2-hydroxyglutarate dehydrogenase
DLAT dihydrolipoamide S-acetyltransferase
DLD dihydrolipoamide dehydrogenase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
FH fumarate hydratase
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
L2HGDH L-2-hydroxyglutarate dehydrogenase
LDHA lactate dehydrogenase A
LDHB lactate dehydrogenase B
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MPC1 mitochondrial pyruvate carrier 1
MPC2 mitochondrial pyruvate carrier 2
NNT nicotinamide nucleotide transhydrogenase
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDHB pyruvate dehydrogenase (lipoamide) beta
PDHX pyruvate dehydrogenase complex, component X
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PPARD peroxisome proliferator-activated receptor delta
RXRA retinoid X receptor, alpha
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUCLG1 succinate-CoA ligase, alpha subunit
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit