Purine metabolism Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). (Gene Ontology, GO_0042278)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-73847
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Genes

33 proteins participating in the Purine metabolism pathway from the Reactome Pathways dataset.

Symbol Name
ADA adenosine deaminase
ADAL adenosine deaminase-like
ADK adenosine kinase
ADSL adenylosuccinate lyase
ADSS adenylosuccinate synthase
ADSSL1 adenylosuccinate synthase like 1
AMPD1 adenosine monophosphate deaminase 1
AMPD2 adenosine monophosphate deaminase 2
AMPD3 adenosine monophosphate deaminase 3
APRT adenine phosphoribosyltransferase
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
CAT catalase
DCK deoxycytidine kinase
DGUOK deoxyguanosine kinase
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GDA guanine deaminase
GMPR guanosine monophosphate reductase
GMPR2 guanosine monophosphate reductase 2
GMPS guanine monphosphate synthase
GPX1 glutathione peroxidase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
NT5C 5', 3'-nucleotidase, cytosolic
NT5C1A 5'-nucleotidase, cytosolic IA
NT5C1B 5'-nucleotidase, cytosolic IB
NT5C2 5'-nucleotidase, cytosolic II
NT5E 5'-nucleotidase, ecto (CD73)
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PFAS phosphoribosylformylglycinamidine synthase
PNP purine nucleoside phosphorylase
PPAT phosphoribosyl pyrophosphate amidotransferase
XDH xanthine dehydrogenase