Psychotic Disorders Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

237 genes associated with the Psychotic Disorders phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACE angiotensin I converting enzyme
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA1A adrenoceptor alpha 1A
AGER advanced glycosylation end product-specific receptor
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKK1 ankyrin repeat and kinase domain containing 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
AUTS2 autism susceptibility candidate 2
AVPR1B arginine vasopressin receptor 1B
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
BACE1 beta-site APP-cleaving enzyme 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BDNF brain-derived neurotrophic factor
BHLHE41 basic helix-loop-helix family, member e41
BSN bassoon presynaptic cytomatrix protein
C9ORF72 chromosome 9 open reading frame 72
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CAPN10 calpain 10
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBS cystathionine-beta-synthase
CDH12 cadherin 12, type 2 (N-cadherin 2)
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRM3 cholinergic receptor, muscarinic 3
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CLINT1 clathrin interactor 1
CLOCK clock circadian regulator
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNR1 cannabinoid receptor 1 (brain)
CNTN4 contactin 4
COL21A1 collagen, type XXI, alpha 1
COMT catechol-O-methyltransferase
CPLX1 complexin 1
CPLX2 complexin 2
CPLX3 complexin 3
CPLX4 complexin 4
CPVL carboxypeptidase, vitellogenic-like
CRH corticotropin releasing hormone
CRHBP corticotropin releasing hormone binding protein
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRP C-reactive protein, pentraxin-related
CRY2 cryptochrome circadian clock 2
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAO D-amino-acid oxidase
DAOA D-amino acid oxidase activator
DBP D site of albumin promoter (albumin D-box) binding protein
DISC1 disrupted in schizophrenia 1
DLG2 discs, large homolog 2 (Drosophila)
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOC2A double C2-like domains, alpha
DPP10 dipeptidyl-peptidase 10 (non-functional)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DTNBP1 dystrobrevin binding protein 1
EGR3 early growth response 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
F5 coagulation factor V (proaccelerin, labile factor)
FAM46A family with sequence similarity 46, member A
FGF2 fibroblast growth factor 2 (basic)
FKBP5 FK506 binding protein 5
FMR1 fragile X mental retardation 1
FOXP2 forkhead box P2
FTO fat mass and obesity associated
FZD3 frizzled class receptor 3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIK4 glutamate receptor, ionotropic, kainate 4
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIP1 glutamate receptor interacting protein 1
GRM3 glutamate receptor, metabotropic 3
GRM7 glutamate receptor, metabotropic 7
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HMG20A high mobility group 20A
HNF4A hepatocyte nuclear factor 4, alpha
HRH1 histamine receptor H1
HSPA8 heat shock 70kDa protein 8
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IL1B interleukin 1, beta
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
INSIG2 insulin induced gene 2
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LEP leptin
LEPR leptin receptor
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAOB monoamine oxidase B
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPT microtubule-associated protein tau
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MECP2 methyl CpG binding protein 2
MIR137 microRNA 137
MOG myelin oligodendrocyte glycoprotein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NFIL3 nuclear factor, interleukin 3 regulated
NLGN1 neuroligin 1
NLGN4X neuroligin 4, X-linked
NOS1 nitric oxide synthase 1 (neuronal)
NOTCH4 notch 4
NPAS2 neuronal PAS domain protein 2
NPY neuropeptide Y
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG1 neuregulin 1
NRXN1 neurexin 1
NSF N-ethylmaleimide-sensitive factor
OLIG2 oligodendrocyte lineage transcription factor 2
OPCML opioid binding protein/cell adhesion molecule-like
OPRM1 opioid receptor, mu 1
PAH phenylalanine hydroxylase
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PBRM1 polybromo 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PER1 period circadian clock 1
PER2 period circadian clock 2
PER3 period circadian clock 3
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PMCH pro-melanin-concentrating hormone
PPARG peroxisome proliferator-activated receptor gamma
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKCA protein kinase C, alpha
PRODH proline dehydrogenase (oxidase) 1
PTK2 protein tyrosine kinase 2
PTPRG protein tyrosine phosphatase, receptor type, G
R3HDML R3H domain containing-like
RAB3A RAB3A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RELN reelin
RGS4 regulator of G-protein signaling 4
RORB RAR-related orphan receptor B
RPGRIP1L RPGRIP1-like
RPL23P8 ribosomal protein L23 pseudogene 8
RTN4R reticulon 4 receptor
S100B S100 calcium binding protein B
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC3 syndecan 3
SH3KBP1 SH3-domain kinase binding protein 1
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
SNPH syntaphilin
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SP8 Sp8 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST7 suppression of tumorigenicity 7
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
STAC SH3 and cysteine rich domain
STX1A syntaxin 1A (brain)
STX7 syntaxin 7
STXBP1 syntaxin binding protein 1
SULT4A1 sulfotransferase family 4A, member 1
SYN3 synapsin III
SYNDIG1 synapse differentiation inducing 1
SYP synaptophysin
SYT1 synaptotagmin I
SYT2 synaptotagmin II
TAAR6 trace amine associated receptor 6
TBX1 T-box 1
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGIF1 TGFB-induced factor homeobox 1
TIMELESS timeless circadian clock
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TPH1 tryptophan hydroxylase 1
TRIM9 tripartite motif containing 9
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSNAX translin-associated factor X
TSPAN7 tetraspanin 7
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VSNL1 visinin-like 1
VTRNA3-1P vault RNA 3-1, pseudogene
VWF von Willebrand factor
WWC1 WW and C2 domain containing 1
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZNF804A zinc finger protein 804A