Psychoses, Substance-Induced Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

79 genes associated with the Psychoses, Substance-Induced phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADORA2A adenosine A2a receptor
ADRA2C adrenoceptor alpha 2C
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANKK1 ankyrin repeat and kinase domain containing 1
ARRB2 arrestin, beta 2
BDNF brain-derived neurotrophic factor
CARTPT CART prepropeptide
CHRM3 cholinergic receptor, muscarinic 3
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CSNK1E casein kinase 1, epsilon
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAOA D-amino acid oxidase activator
DISC1 disrupted in schizophrenia 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ESR1 estrogen receptor 1
FAAH fatty acid amide hydrolase
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FKBP5 FK506 binding protein 5
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GCLM glutamate-cysteine ligase, modifier subunit
GPM6A glycoprotein M6A
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
LRRTM1 leucine rich repeat transmembrane neuronal 1
MAOA monoamine oxidase A
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NOS1 nitric oxide synthase 1 (neuronal)
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NRG1 neuregulin 1
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDYN prodynorphin
PICK1 protein interacting with PRKCA 1
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PRDM2 PR domain containing 2, with ZNF domain
PRODH proline dehydrogenase (oxidase) 1
RGS2 regulator of G-protein signaling 2
RGS4 regulator of G-protein signaling 4
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SIRT1 sirtuin 1
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD2 superoxide dismutase 2, mitochondrial
TBX1 T-box 1