Psychomotor Performance Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description The coordination of a sensory or ideational (cognitive) process and a motor activity. (Experimental Factor Ontology, EFO_0004362)
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Genes

117 genes associated with the Psychomotor Performance phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ADA adenosine deaminase
ADORA2A adenosine A2a receptor
ADRA1A adrenoceptor alpha 1A
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMBRA1 autophagy/beclin-1 regulator 1
ANKK1 ankyrin repeat and kinase domain containing 1
APOC1 apolipoprotein C-I
APOE apolipoprotein E
ARSG arylsulfatase G
ATP10A ATPase, class V, type 10A
BAIAP3 BAI1-associated protein 3
BDNF brain-derived neurotrophic factor
BICC1 BicC family RNA binding protein 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CDH13 cadherin 13
CHMP2B charged multivesicular body protein 2B
CHRM2 cholinergic receptor, muscarinic 2
CHRM4 cholinergic receptor, muscarinic 4
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CPM carboxypeptidase M
CPOX coproporphyrinogen oxidase
CREB1 cAMP responsive element binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DGKZ diacylglycerol kinase, zeta
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DTNBP1 dystrobrevin binding protein 1
DYX1C1 dyslexia susceptibility 1 candidate 1
EGR3 early growth response 3
FADS2 fatty acid desaturase 2
FTO fat mass and obesity associated
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM7 glutamate receptor, metabotropic 7
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOMER1 homer scaffolding protein 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
HTT huntingtin
IL1B interleukin 1, beta
IL6 interleukin 6
KDR kinase insert domain receptor
LMX1A LIM homeobox transcription factor 1, alpha
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MDK midkine (neurite growth-promoting factor 2)
MECP2 methyl CpG binding protein 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NOS1 nitric oxide synthase 1 (neuronal)
NRG1 neuregulin 1
NRG3 neuregulin 3
OPRM1 opioid receptor, mu 1
PER2 period circadian clock 2
PER3 period circadian clock 3
PINK1 PTEN induced putative kinase 1
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRNP prion protein
RGS4 regulator of G-protein signaling 4
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TACR1 tachykinin receptor 1
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TH tyrosine hydroxylase
TNF tumor necrosis factor
TOR1A torsin family 1, member A (torsin A)
TPH2 tryptophan hydroxylase 2
UBE3A ubiquitin protein ligase E3A
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UGT8 UDP glycosyltransferase 8
WWC1 WW and C2 domain containing 1
ZNF804A zinc finger protein 804A