Prostatic Hyperplasia Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

92 genes associated with the Prostatic Hyperplasia phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADRA1A adrenoceptor alpha 1A
ADRB3 adrenoceptor beta 3
AGTR1 angiotensin II receptor, type 1
AKR1C3 aldo-keto reductase family 1, member C3
AR androgen receptor
ARL11 ADP-ribosylation factor-like 11
CASC8 cancer susceptibility candidate 8 (non-protein coding)
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COMT catechol-O-methyltransferase
CTBP2 C-terminal binding protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAB2IP DAB2 interacting protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EGFR epidermal growth factor receptor
EHBP1 EH domain binding protein 1
ELAC2 elaC ribonuclease Z 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
GLO1 glyoxalase I
GNAS GNAS complex locus
GNMT glycine N-methyltransferase
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HNF1B HNF1 homeobox B
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL10RB interleukin 10 receptor, beta
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
IRX4 iroquois homeobox 4
ISPD isoprenoid synthase domain containing
ITGA6 integrin, alpha 6
JAZF1 JAZF zinc finger 1
KLF6 Kruppel-like factor 6
KLK3 kallikrein-related peptidase 3
LMTK2 lemur tyrosine kinase 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MLH1 mutL homolog 1
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
MSR1 macrophage scavenger receptor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
PCA3 prostate cancer associated 3 (non-protein coding)
PON1 paraoxonase 1
PSAP prosaposin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RFX6 regulatory factor X, 6
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TYR tyrosinase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor