Prostatic Hyperplasia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D011470
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Genes

141 genes/proteins associated with the disease Prostatic Hyperplasia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
KLK3 kallikrein-related peptidase 3 2.88009
FGF7 fibroblast growth factor 7 2.88009
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2.88009
PRL prolactin 2.88009
ADRA1D adrenoceptor alpha 1D 1.63899
ADRA1A adrenoceptor alpha 1A 1.55133
ADRA1B adrenoceptor alpha 1B 1.52642
ACTA1 actin, alpha 1, skeletal muscle 1.43946
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.37418
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 1.35012
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.31297
LHB luteinizing hormone beta polypeptide 1.30056
IGF1 insulin-like growth factor 1 (somatomedin C) 1.29317
AR androgen receptor 1.29103
PKP4 plakophilin 4 1.26794
ASRGL1 asparaginase like 1 1.26267
CCL5 chemokine (C-C motif) ligand 5 1.25463
RAI14 retinoic acid induced 14 1.2437
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 1.22696
TGFB3 transforming growth factor, beta 3 1.22016
CNIH2 cornichon family AMPA receptor auxiliary protein 2 1.2046
EFTUD1 elongation factor Tu GTP binding domain containing 1 1.2046
BCL2 B-cell CLL/lymphoma 2 1.20361
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 1.1977
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 1.19737
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 1.19345
PCNA proliferating cell nuclear antigen 1.18948
PRPF38A pre-mRNA processing factor 38A 1.18554
RTN4R reticulon 4 receptor 1.18554
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1.17728
WDR62 WD repeat domain 62 1.17662
HAUS8 HAUS augmin-like complex, subunit 8 1.16833
CD7 CD7 molecule 1.16799
NUP133 nucleoporin 133kDa 1.16799
RTN2 reticulon 2 1.16799
CDK4 cyclin-dependent kinase 4 1.16666
GREB1 growth regulation by estrogen in breast cancer 1 1.166
PACS1 phosphofurin acidic cluster sorting protein 1 1.16001
DPF1 D4, zinc and double PHD fingers family 1 1.16001
ACTA2 actin, alpha 2, smooth muscle, aorta 1.15425
IYD iodotyrosine deiodinase 1.14507
FMO5 flavin containing monooxygenase 5 1.1437
THOC1 THO complex 1 1.13758
CCDC50 coiled-coil domain containing 50 1.13758
PAK1IP1 PAK1 interacting protein 1 1.13758
BAX BCL2-associated X protein 1.13552
CGA glycoprotein hormones, alpha polypeptide 1.13484
NUP107 nucleoporin 107kDa 1.13075
RDM1 RAD52 motif containing 1 1.13075
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.12805
FAM105A family with sequence similarity 105, member A 1.12426
ESR1 estrogen receptor 1 1.11877
WDR36 WD repeat domain 36 1.11116
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.10769
VAMP5 vesicle-associated membrane protein 5 1.10596
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.10527
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.10353
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.10246
BMP7 bone morphogenetic protein 7 1.09998
SH3YL1 SH3 and SYLF domain containing 1 1.09927
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.09786
PEX13 peroxisomal biogenesis factor 13 1.09401
PHTF2 putative homeodomain transcription factor 2 1.09401
LRR1 leucine rich repeat protein 1 1.09366
DGAT2 diacylglycerol O-acyltransferase 2 1.09297
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.09047
GAL galanin/GMAP prepropeptide 1.09047
SLC39A11 solute carrier family 39, member 11 1.08797
FOS FBJ murine osteosarcoma viral oncogene homolog 1.08762
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.08762
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.08726
CYP3A cytochrome P450, family 3, subfamily A 1.08584
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 1.08301
STC2 stanniocalcin 2 1.08301
GFAP glial fibrillary acidic protein 1.08231
CAPN12 calpain 12 1.08055
LRRC29 leucine rich repeat containing 29 1.08055
GJB2 gap junction protein, beta 2, 26kDa 1.07911
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.0784
TMPO thymopoietin 1.0784
MYL7 myosin, light chain 7, regulatory 1.07804
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 1.07804
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 1.07732
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.0766
SLC44A4 solute carrier family 44, member 4 1.07234
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 1.07234
COL1A1 collagen, type I, alpha 1 1.06808
DEGS1 delta(4)-desaturase, sphingolipid 1 1.06734
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.06625
GSX1 GS homeobox 1 1.06297
PDK3 pyruvate dehydrogenase kinase, isozyme 3 1.06261
IQGAP3 IQ motif containing GTPase activating protein 3 1.06225
DOCK8 dedicator of cytokinesis 8 1.05793
NUP155 nucleoporin 155kDa 1.05757
CRP C-reactive protein, pentraxin-related 1.05535
MGLL monoglyceride lipase 1.05461
KIF5B kinesin family member 5B 1.05386
FGD4 FYVE, RhoGEF and PH domain containing 4 1.04831
GHR growth hormone receptor 1.04831
QPCTL glutaminyl-peptide cyclotransferase-like 1.04611
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.04465
COLEC12 collectin sub-family member 12 1.04427
OSBPL1A oxysterol binding protein-like 1A 1.04389
PPIC peptidylprolyl isomerase C (cyclophilin C) 1.04389
LBR lamin B receptor 1.04389
RFC2 replication factor C (activator 1) 2, 40kDa 1.04389
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.04314
TGFB1 transforming growth factor, beta 1 1.04276
G6PD glucose-6-phosphate dehydrogenase 1.04239
HNF4A hepatocyte nuclear factor 4, alpha 1.04201
NOP58 NOP58 ribonucleoprotein 1.03939
EAF2 ELL associated factor 2 1.03641
MIR1915 microRNA 1915 1.03604
VIM vimentin 1.03567
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 1.0353
GPR137B G protein-coupled receptor 137B 1.0353
CPD carboxypeptidase D 1.03493
MYL1 myosin, light chain 1, alkali; skeletal, fast 1.03345
PRIMA1 proline rich membrane anchor 1 1.03271
ARMC7 armadillo repeat containing 7 1.03197
DMBX1 diencephalon/mesencephalon homeobox 1 1.03197
PLAC1 placenta-specific 1 1.03197
PGM3 phosphoglucomutase 3 1.03122
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.03084
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.02746
ZYX zyxin 1.02671
CAT catalase 1.0241
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 1.02336
PRKD1 protein kinase D1 1.02336
EXOSC2 exosome component 2 1.02299
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.0189
HMGB1 high mobility group box 1 1.0189
GPR37L1 G protein-coupled receptor 37 like 1 1.01852
PAX1 paired box 1 1.01852
PADI3 peptidyl arginine deiminase, type III 1.01776
TK1 thymidine kinase 1, soluble 1.01739
NOS2 nitric oxide synthase 2, inducible 1.01549
NID2 nidogen 2 (osteonidogen) 1.01512
LPL lipoprotein lipase 1.01212
NCAPD2 non-SMC condensin I complex, subunit D2 1.01099
CCND1 cyclin D1 1.01062