Prestwick-984-7323 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the Prestwick-984-7323 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALS2CL ALS2 C-terminal like
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP9A ATPase, class II, type 9A
AURKA aurora kinase A
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF63 chromosome 11 open reading frame 63
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCP110 centriolar coiled coil protein 110kDa
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CYLD cylindromatosis (turban tumor syndrome)
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DAGLA diacylglycerol lipase, alpha
DCTN1 dynactin 1
DICER1 dicer 1, ribonuclease type III
DUSP10 dual specificity phosphatase 10
DUSP9 dual specificity phosphatase 9
DUX1 double homeobox 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHD1 EH-domain containing 1
EPHA1 EPH receptor A1
EPHB1 EPH receptor B1
EPOR erythropoietin receptor
EVA1B eva-1 homolog B (C. elegans)
FBXL18 F-box and leucine-rich repeat protein 18
FOXG1 forkhead box G1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GK glycerol kinase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HOMER3 homer scaffolding protein 3
HOXB5 homeobox B5
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
LOC257152 uncharacterized LOC257152
LRP12 low density lipoprotein receptor-related protein 12
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MTERF4 mitochondrial transcription termination factor 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR3 myotubularin related protein 3
MUC1 mucin 1, cell surface associated
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCKIPSD NCK interacting protein with SH3 domain
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMT2 N-myristoyltransferase 2
NUP88 nucleoporin 88kDa
PCDH12 protocadherin 12
PDCD2 programmed cell death 2
PDE8B phosphodiesterase 8B
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLIN2 perilipin 2
PMEL premelanosome protein
PML promyelocytic leukemia
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDX2 peroxiredoxin 2
PROS1 protein S (alpha)
PRUNE2 prune homolog 2 (Drosophila)
RAB36 RAB36, member RAS oncogene family
RBM19 RNA binding motif protein 19
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
RPS2 ribosomal protein S2
RREB1 ras responsive element binding protein 1
SAMD4A sterile alpha motif domain containing 4A
SBF1 SET binding factor 1
SDC2 syndecan 2
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC17A2 solute carrier family 17, member 2
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SUN2 Sad1 and UNC84 domain containing 2
SYCE1L synaptonemal complex central element protein 1-like
TBC1D2 TBC1 domain family, member 2
TBC1D4 TBC1 domain family, member 4
TNK1 tyrosine kinase, non-receptor, 1
TRAK1 trafficking protein, kinesin binding 1
TRBC1 T cell receptor beta constant 1
TRIB2 tribbles pseudokinase 2
TRIM3 tripartite motif containing 3
VAV2 vav 2 guanine nucleotide exchange factor
ZCCHC14 zinc finger, CCHC domain containing 14
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF500 zinc finger protein 500
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARL15 ADP-ribosylation factor-like 15
ATAD2B ATPase family, AAA domain containing 2B
ATAD3A ATPase family, AAA domain containing 3A
ATP11B ATPase, class VI, type 11B
BEX4 brain expressed, X-linked 4
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF80 chromosome 17 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C5 complement component 5
C5ORF45 chromosome 5 open reading frame 45
CCDC88C coiled-coil domain containing 88C
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP97 centrosomal protein 97kDa
CLCN2 chloride channel, voltage-sensitive 2
DCAF13 DDB1 and CUL4 associated factor 13
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DMTN dematin actin binding protein
DNAL4 dynein, axonemal, light chain 4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELOVL4 ELOVL fatty acid elongase 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM114A2 family with sequence similarity 114, member A2
FAM134C family with sequence similarity 134, member C
FRS2 fibroblast growth factor receptor substrate 2
FYCO1 FYVE and coiled-coil domain containing 1
GNL1 guanine nucleotide binding protein-like 1
GPC3 glypican 3
GPX2 glutathione peroxidase 2
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GSTT1 glutathione S-transferase theta 1
INCENP inner centromere protein antigens 135/155kDa
KLF7 Kruppel-like factor 7 (ubiquitous)
KRI1 KRI1 homolog (S. cerevisiae)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIAS lipoic acid synthetase
LRRC37A2 leucine rich repeat containing 37, member A2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MAST3 microtubule associated serine/threonine kinase 3
MFAP2 microfibrillar-associated protein 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MON1B MON1 secretory trafficking family member B
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NHEJ1 nonhomologous end-joining factor 1
NPFFR1 neuropeptide FF receptor 1
NRSN2 neurensin 2
OGFRL1 opioid growth factor receptor-like 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLA2G15 phospholipase A2, group XV
PRICKLE3 prickle homolog 3 (Drosophila)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF25 ring finger protein 25
RPAP1 RNA polymerase II associated protein 1
RUFY2 RUN and FYVE domain containing 2
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2D4A SH2 domain containing 4A
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SORBS3 sorbin and SH3 domain containing 3
SOX12 SRY (sex determining region Y)-box 12
SP140L SP140 nuclear body protein-like
SPINK4 serine peptidase inhibitor, Kazal type 4
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX1A syntaxin 1A (brain)
SYT17 synaptotagmin XVII
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TRIM5 tripartite motif containing 5
TSPAN5 tetraspanin 5
TWF2 twinfilin actin binding protein 2
UNC119 unc-119 homolog (C. elegans)
VAX2 ventral anterior homeobox 2
WDR60 WD repeat domain 60
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC24 zinc finger, DHHC-type containing 24
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF212 zinc finger protein 212
ZNF324 zinc finger protein 324
ZNF510 zinc finger protein 510
ZNF557 zinc finger protein 557
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31