Prestwick-967-7346 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the Prestwick-967-7346 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
AHI1 Abelson helper integration site 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARMCX2 armadillo repeat containing, X-linked 2
ATXN2L ataxin 2-like
AURKA aurora kinase A
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAG4 BCL2-associated athanogene 4
CACFD1 calcium channel flower domain containing 1
CACYBP calcyclin binding protein
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD8A CD8a molecule
CDC25C cell division cycle 25C
CEP162 centrosomal protein 162kDa
CLCN5 chloride channel, voltage-sensitive 5
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
DPF1 D4, zinc and double PHD fingers family 1
DRD2 dopamine receptor D2
DVL2 dishevelled segment polarity protein 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EYA3 EYA transcriptional coactivator and phosphatase 3
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPR143 G protein-coupled receptor 143
GPR37L1 G protein-coupled receptor 37 like 1
GRK5 G protein-coupled receptor kinase 5
HSF2 heat shock transcription factor 2
IGFBP5 insulin-like growth factor binding protein 5
ING4 inhibitor of growth family, member 4
INPP1 inositol polyphosphate-1-phosphatase
JADE2 jade family PHD finger 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF12 Kruppel-like factor 12
LOC257152 uncharacterized LOC257152
LRP12 low density lipoprotein receptor-related protein 12
MAP1A microtubule-associated protein 1A
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4 microtubule-associated protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED14 mediator complex subunit 14
MLXIP MLX interacting protein
MOCS1 molybdenum cofactor synthesis 1
MOGAT2 monoacylglycerol O-acyltransferase 2
MYLK myosin light chain kinase
MYOF myoferlin
MZF1 myeloid zinc finger 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NOL10 nucleolar protein 10
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OASL 2'-5'-oligoadenylate synthetase-like
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OVGP1 oviductal glycoprotein 1, 120kDa
PAX2 paired box 2
PDAP1 PDGFA associated protein 1
PDGFA platelet-derived growth factor alpha polypeptide
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMCH pro-melanin-concentrating hormone
PRB3 proline-rich protein BstNI subfamily 3
PROS1 protein S (alpha)
PSG1 pregnancy specific beta-1-glycoprotein 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PXN paxillin
RAB30 RAB30, member RAS oncogene family
RANBP1 RAN binding protein 1
RASL11B RAS-like, family 11, member B
RBMS2 RNA binding motif, single stranded interacting protein 2
RNF2 ring finger protein 2
RPS14 ribosomal protein S14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SBF1 SET binding factor 1
SIRT5 sirtuin 5
SLC45A2 solute carrier family 45, member 2
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SRP72 signal recognition particle 72kDa
SUGP1 SURP and G patch domain containing 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D5 TBC1 domain family, member 5
TMPRSS2 transmembrane protease, serine 2
TNK1 tyrosine kinase, non-receptor, 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC9 trafficking protein particle complex 9
TTC9 tetratricopeptide repeat domain 9
UBXN1 UBX domain protein 1
WAS Wiskott-Aldrich syndrome
WIZ widely interspaced zinc finger motifs
WNK1 WNK lysine deficient protein kinase 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF821 zinc finger protein 821
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
BTBD2 BTB (POZ) domain containing 2
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
C22ORF29 chromosome 22 open reading frame 29
CAPN15 calpain 15
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD302 CD302 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPT centromere protein T
CHIC2 cysteine-rich hydrophobic domain 2
CLCF1 cardiotrophin-like cytokine factor 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNALI1 dynein, axonemal, light intermediate chain 1
ECH1 enoyl CoA hydratase 1, peroxisomal
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
FAAH fatty acid amide hydrolase
FBXW12 F-box and WD repeat domain containing 12
FLJ11710 uncharacterized protein FLJ11710
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAREM GRB2 associated, regulator of MAPK1
GBP2 guanylate binding protein 2, interferon-inducible
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPC3 glypican 3
GRB7 growth factor receptor-bound protein 7
GSTT1 glutathione S-transferase theta 1
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HPN hepsin
IFI6 interferon, alpha-inducible protein 6
IFT81 intraflagellar transport 81
IMPACT impact RWD domain protein
INCENP inner centromere protein antigens 135/155kDa
INPPL1 inositol polyphosphate phosphatase-like 1
IPO8 importin 8
IRF1 interferon regulatory factor 1
IRF9 interferon regulatory factor 9
ITPKB inositol-trisphosphate 3-kinase B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM5C lysine (K)-specific demethylase 5C
KLF7 Kruppel-like factor 7 (ubiquitous)
KREMEN2 kringle containing transmembrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC730101 uncharacterized LOC730101
MATK megakaryocyte-associated tyrosine kinase
MCOLN3 mucolipin 3
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL2B methyltransferase like 2B
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MNS1 meiosis-specific nuclear structural 1
MXD3 MAX dimerization protein 3
ONECUT2 one cut homeobox 2
PCDHB8 protocadherin beta 8
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PPT2 palmitoyl-protein thioesterase 2
RASA2 RAS p21 protein activator 2
RBL1 retinoblastoma-like 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCN1B sodium channel, voltage gated, type I beta subunit
SERTAD3 SERTA domain containing 3
SH2D4A SH2 domain containing 4A
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SNAI2 snail family zinc finger 2
SSBP3 single stranded DNA binding protein 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBX19 T-box 19
TCTN1 tectonic family member 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMCC2 transmembrane and coiled-coil domain family 2
ULBP2 UL16 binding protein 2
URGCP upregulator of cell proliferation
USB1 U6 snRNA biogenesis 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
ZFP30 ZFP30 zinc finger protein
ZMYM3 zinc finger, MYM-type 3
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF227 zinc finger protein 227
ZNF276 zinc finger protein 276
ZNF432 zinc finger protein 432
ZNF506 zinc finger protein 506
ZNF623 zinc finger protein 623