Prestwick-920-5475 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


196 genes differentially expressed following the Prestwick-920-5475 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ANGEL2 angel homolog 2 (Drosophila)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BIN1 bridging integrator 1
BMP1 bone morphogenetic protein 1
CCNJL cyclin J-like
CD70 CD70 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK17 cyclin-dependent kinase 17
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CORO2B coronin, actin binding protein, 2B
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CUL9 cullin 9
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAGLA diacylglycerol lipase, alpha
DAZL deleted in azoospermia-like
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DRD2 dopamine receptor D2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ETV5 ets variant 5
FBXL7 F-box and leucine-rich repeat protein 7
FOXN2 forkhead box N2
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALR3 galanin receptor 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPM6B glycoprotein M6B
GPR176 G protein-coupled receptor 176
GPR85 G protein-coupled receptor 85
GSTTP1 glutathione S-transferase theta pseudogene 1
HES2 hes family bHLH transcription factor 2
HEXA hexosaminidase A (alpha polypeptide)
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
HP1BP3 heterochromatin protein 1, binding protein 3
IFI6 interferon, alpha-inducible protein 6
IL1RN interleukin 1 receptor antagonist
INPP5J inositol polyphosphate-5-phosphatase J
JAM3 junctional adhesion molecule 3
KIAA0125 KIAA0125
KLHL25 kelch-like family member 25
KRT17 keratin 17, type I
LGALS9 lectin, galactoside-binding, soluble, 9
LIG4 ligase IV, DNA, ATP-dependent
LOC257152 uncharacterized LOC257152
MAPK13 mitogen-activated protein kinase 13
MBD2 methyl-CpG binding domain protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKL1 megakaryoblastic leukemia (translocation) 1
NOL10 nucleolar protein 10
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFM1 olfactomedin 1
OSMR oncostatin M receptor
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIAS4 protein inhibitor of activated STAT, 4
PKNOX2 PBX/knotted 1 homeobox 2
PLCG1 phospholipase C, gamma 1
PML promyelocytic leukemia
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
RAD52 RAD52 homolog (S. cerevisiae)
RANBP1 RAN binding protein 1
RAP2B RAP2B, member of RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFPL2 ret finger protein-like 2
RPL35A ribosomal protein L35a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRBP1 ribosome binding protein 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERHL2 serine hydrolase-like 2
SFTPC surfactant protein C
SKIL SKI-like proto-oncogene
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOX9 SRY (sex determining region Y)-box 9
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STEAP4 STEAP family member 4
STX2 syntaxin 2
STX3 syntaxin 3
STX7 syntaxin 7
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TADA3 transcriptional adaptor 3
TBC1D5 TBC1 domain family, member 5
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV6 transient receptor potential cation channel, subfamily V, member 6
USP22 ubiquitin specific peptidase 22
VN1R1 vomeronasal 1 receptor 1
ZBTB22 zinc finger and BTB domain containing 22
ZFPL1 zinc finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF137P zinc finger protein 137, pseudogene
ZNF287 zinc finger protein 287
ZNF646 zinc finger protein 646
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ADAP2 ArfGAP with dual PH domains 2
ADTRP androgen-dependent TFPI-regulating protein
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ATP13A2 ATPase type 13A2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF88 chromosome 10 open reading frame 88
C1QTNF3 C1q and tumor necrosis factor related protein 3
CBX7 chromobox homolog 7
CDK20 cyclin-dependent kinase 20
CDK5 cyclin-dependent kinase 5
CEP97 centrosomal protein 97kDa
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHMP6 charged multivesicular body protein 6
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCP1A decapping mRNA 1A
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGKD diacylglycerol kinase, delta 130kDa
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DVL1 dishevelled segment polarity protein 1
ELP3 elongator acetyltransferase complex subunit 3
ETAA1 Ewing tumor-associated antigen 1
FBXO31 F-box protein 31
FMO4 flavin containing monooxygenase 4
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GID4 GID complex subunit 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSK3A glycogen synthase kinase 3 alpha
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
IDI2-AS1 IDI2 antisense RNA 1
INF2 inverted formin, FH2 and WH2 domain containing
IRF6 interferon regulatory factor 6
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KLHL36 kelch-like family member 36
KPTN kaptin (actin binding protein)
KREMEN2 kringle containing transmembrane protein 2
LAMA3 laminin, alpha 3
LMCD1 LIM and cysteine-rich domains 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP2 low density lipoprotein receptor-related protein 2
LYRM9 LYR motif containing 9
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MB myoglobin
MBNL3 muscleblind-like splicing regulator 3
METTL16 methyltransferase like 16
MRPL41 mitochondrial ribosomal protein L41
MYL5 myosin, light chain 5, regulatory
MYO1F myosin IF
NIPAL2 NIPA-like domain containing 2
NPIPB15 nuclear pore complex interacting protein family, member B15
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G3 phospholipase A2, group III
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRMT7 protein arginine methyltransferase 7
PRSS8 protease, serine, 8
RPL23AP32 ribosomal protein L23a pseudogene 32
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAI2 snail family zinc finger 2
SPINK5 serine peptidase inhibitor, Kazal type 5
STX1A syntaxin 1A (brain)
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAGLN transgelin
TESC tescalcin
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMC7 transmembrane channel-like 7
TMEM104 transmembrane protein 104
TMEM53 transmembrane protein 53
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRAPPC2 trafficking protein particle complex 2
TRIM66 tripartite motif containing 66
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBQLN4 ubiquilin 4
VGF VGF nerve growth factor inducible
ZBED1 zinc finger, BED-type containing 1
ZC3H3 zinc finger CCCH-type containing 3
ZNF205 zinc finger protein 205
ZNF263 zinc finger protein 263
ZNF34 zinc finger protein 34
ZNF408 zinc finger protein 408
ZNF747 zinc finger protein 747