Prestwick-685-2188 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


197 genes differentially expressed following the Prestwick-685-2188 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
ADORA1 adenosine A1 receptor
AKAP6 A kinase (PRKA) anchor protein 6
C17ORF59 chromosome 17 open reading frame 59
C19ORF73 chromosome 19 open reading frame 73
C9ORF9 chromosome 9 open reading frame 9
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD5 CD5 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
COL7A1 collagen, type VII, alpha 1
CREBZF CREB/ATF bZIP transcription factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
DAO D-amino-acid oxidase
DDO D-aspartate oxidase
DLL3 delta-like 3 (Drosophila)
DSC3 desmocollin 3
EPHB1 EPH receptor B1
EPN1 epsin 1
EPN2 epsin 2
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FLT1 fms-related tyrosine kinase 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FUT2 fucosyltransferase 2 (secretor status included)
GJA8 gap junction protein, alpha 8, 50kDa
GPATCH4 G patch domain containing 4
GPR1 G protein-coupled receptor 1
GPR35 G protein-coupled receptor 35
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIST1H4H histone cluster 1, H4h
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOXC11 homeobox C11
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGLJ3 immunoglobulin lambda joining 3
JPH3 junctophilin 3
KIF3C kinesin family member 3C
KIF5A kinesin family member 5A
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF3 Kruppel-like factor 3 (basic)
KLHL35 kelch-like family member 35
KLK13 kallikrein-related peptidase 13
KSR1 kinase suppressor of ras 1
LAMP3 lysosomal-associated membrane protein 3
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LIN7B lin-7 homolog B (C. elegans)
LMNA lamin A/C
MARC1 mitochondrial amidoxime reducing component 1
MMP19 matrix metallopeptidase 19
MT1G metallothionein 1G
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCAPH2 non-SMC condensin II complex, subunit H2
NES nestin
NNAT neuronatin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PAM peptidylglycine alpha-amidating monooxygenase
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11X protocadherin 11 X-linked
PDE4DIP phosphodiesterase 4D interacting protein
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKNOX2 PBX/knotted 1 homeobox 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEC plectin
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKG2 protein kinase, cGMP-dependent, type II
PRODH2 proline dehydrogenase (oxidase) 2
PTPRF protein tyrosine phosphatase, receptor type, F
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RASAL2 RAS protein activator like 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIN2 Ras and Rab interactor 2
RPL13P5 ribosomal protein L13 pseudogene 5
SFTPC surfactant protein C
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT4 sirtuin 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLN sarcolipin
SPAG8 sperm associated antigen 8
SPRR1B small proline-rich protein 1B
SYCE1L synaptonemal complex central element protein 1-like
TCF3 transcription factor 3
TG thyroglobulin
THRB thyroid hormone receptor, beta
TNN tenascin N
TRIM15 tripartite motif containing 15
TTC38 tetratricopeptide repeat domain 38
UBE2I ubiquitin-conjugating enzyme E2I
ULK2 unc-51 like autophagy activating kinase 2
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WDR55 WD repeat domain 55
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD17B abhydrolase domain containing 17B
ADGRG2 adhesion G protein-coupled receptor G2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANXA2P2 annexin A2 pseudogene 2
ARRB1 arrestin, beta 1
ARSB arylsulfatase B
ASGR2 asialoglycoprotein receptor 2
ASPN asporin
C17ORF70 chromosome 17 open reading frame 70
C6ORF47 chromosome 6 open reading frame 47
CAPN15 calpain 15
CCDC186 coiled-coil domain containing 186
CDKL3 cyclin-dependent kinase-like 3
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CHMP6 charged multivesicular body protein 6
CHST10 carbohydrate sulfotransferase 10
CIDEC cell death-inducing DFFA-like effector c
CLEC2D C-type lectin domain family 2, member D
CORT cortistatin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CROT carnitine O-octanoyltransferase
CTRL chymotrypsin-like
CTSD cathepsin D
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
EPX eosinophil peroxidase
FAM86B1 family with sequence similarity 86, member B1
FKBP14 FK506 binding protein 14, 22 kDa
FSTL3 follistatin-like 3 (secreted glycoprotein)
GK3P glycerol kinase 3 pseudogene
GLTP glycolipid transfer protein
GPR21 G protein-coupled receptor 21
GRPR gastrin-releasing peptide receptor
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2AI histone cluster 1, H2ai
HIST1H2BI histone cluster 1, H2bi
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL12RB1 interleukin 12 receptor, beta 1
IL22 interleukin 22
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
IQCC IQ motif containing C
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD20 potassium channel tetramerization domain containing 20
KIAA0754 KIAA0754
KIF20A kinesin family member 20A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL28 kelch-like family member 28
LIG3 ligase III, DNA, ATP-dependent
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAK male germ cell-associated kinase
MAPK3 mitogen-activated protein kinase 3
METRN meteorin, glial cell differentiation regulator
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYBPH myosin binding protein H
NSD1 nuclear receptor binding SET domain protein 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PDGFD platelet derived growth factor D
PDZD7 PDZ domain containing 7
PLCD1 phospholipase C, delta 1
POLL polymerase (DNA directed), lambda
POM121L2 POM121 transmembrane nucleoporin-like 2
PTPRS protein tyrosine phosphatase, receptor type, S
RHBDD3 rhomboid domain containing 3
RHOH ras homolog family member H
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
SCRN3 secernin 3
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SNAI1 snail family zinc finger 1
STX11 syntaxin 11
SYNDIG1 synapse differentiation inducing 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN transgelin
TBC1D19 TBC1 domain family, member 19
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMP2 TIMP metallopeptidase inhibitor 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM120B transmembrane protein 120B
TMEM212 transmembrane protein 212
TP53I3 tumor protein p53 inducible protein 3
TPM3 tropomyosin 3
TRAF1 TNF receptor-associated factor 1
VASH2 vasohibin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WASF3 WAS protein family, member 3
WDR62 WD repeat domain 62
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF219 zinc finger protein 219
ZNF37BP zinc finger protein 37B, pseudogene
ZNF747 zinc finger protein 747