Prestwick-642-2815 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the Prestwick-642-2815 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ACTL8 actin-like 8
ALS2CL ALS2 C-terminal like
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP11A ATPase, class VI, type 11A
CABIN1 calcineurin binding protein 1
CACTIN cactin, spliceosome C complex subunit
CAPN15 calpain 15
CD1E CD1e molecule
CDC42 cell division cycle 42
CGA glycoprotein hormones, alpha polypeptide
CHD9 chromodomain helicase DNA binding protein 9
CHST10 carbohydrate sulfotransferase 10
CLCN7 chloride channel, voltage-sensitive 7
CLDN11 claudin 11
CORO7 coronin 7
CPNE7 copine VII
CRMP1 collapsin response mediator protein 1
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
DNAH17 dynein, axonemal, heavy chain 17
DOK4 docking protein 4
DSTYK dual serine/threonine and tyrosine protein kinase
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
ETV6 ets variant 6
FAM46C family with sequence similarity 46, member C
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GMPR guanosine monophosphate reductase
HEG1 heart development protein with EGF-like domains 1
HSF1 heat shock transcription factor 1
IL2RG interleukin 2 receptor, gamma
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KDM5C lysine (K)-specific demethylase 5C
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KLHL25 kelch-like family member 25
KRT15 keratin 15, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAX1 lymphocyte transmembrane adaptor 1
LPPR2 lipid phosphate phosphatase-related protein type 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MIER2 mesoderm induction early response 1, family member 2
MMP11 matrix metallopeptidase 11
MMP25 matrix metallopeptidase 25
N4BP2L2 NEDD4 binding protein 2-like 2
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAGLU N-acetylglucosaminidase, alpha
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
ODAM odontogenic, ameloblast asssociated
ONECUT2 one cut homeobox 2
ORAI2 ORAI calcium release-activated calcium modulator 2
PCDHA5 protocadherin alpha 5
PCDHB3 protocadherin beta 3
PDLIM4 PDZ and LIM domain 4
PIGR polymeric immunoglobulin receptor
PLCD1 phospholipase C, delta 1
PNPLA6 patatin-like phospholipase domain containing 6
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PRDX2 peroxiredoxin 2
PRR5 proline rich 5 (renal)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTN pleiotrophin
PVRL3 poliovirus receptor-related 3
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF19B ring finger protein 19B
S100A9 S100 calcium binding protein A9
SARM1 sterile alpha and TIR motif containing 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SH3BP2 SH3-domain binding protein 2
SH3GL3 SH3-domain GRB2-like 3
SIRT3 sirtuin 3
SOGA1 suppressor of glucose, autophagy associated 1
ST5 suppression of tumorigenicity 5
SYNDIG1 synapse differentiation inducing 1
TAOK2 TAO kinase 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TJAP1 tight junction associated protein 1 (peripheral)
TM4SF1 transmembrane 4 L six family member 1
TMEM63A transmembrane protein 63A
TRA2A transformer 2 alpha homolog (Drosophila)
TRIM21 tripartite motif containing 21
TTC38 tetratricopeptide repeat domain 38
UBXN6 UBX domain protein 6
USP32 ubiquitin specific peptidase 32
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDR62 WD repeat domain 62
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF3 zinc finger protein 3
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRE5 adhesion G protein-coupled receptor E5
AHDC1 AT hook, DNA binding motif, containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
BMP4 bone morphogenetic protein 4
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF21 chromosome 11 open reading frame 21
C1ORF105 chromosome 1 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDH10 cadherin 10, type 2 (T2-cadherin)
CEP97 centrosomal protein 97kDa
CHRM3 cholinergic receptor, muscarinic 3
CLDN15 claudin 15
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNTN1 contactin 1
CPTP ceramide-1-phosphate transfer protein
DGAT1 diacylglycerol O-acyltransferase 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
ENO2 enolase 2 (gamma, neuronal)
ETAA1 Ewing tumor-associated antigen 1
EXO5 exonuclease 5
FAM86C1 family with sequence similarity 86, member C1
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP14 FK506 binding protein 14, 22 kDa
FMOD fibromodulin
FRAS1 Fraser extracellular matrix complex subunit 1
GAMT guanidinoacetate N-methyltransferase
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H2AJ histone cluster 1, H2aj
HIST1H3B histone cluster 1, H3b
HIST1H3E histone cluster 1, H3e
INHBE inhibin, beta E
INPP1 inositol polyphosphate-1-phosphatase
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNK5 potassium channel, two pore domain subfamily K, member 5
KLF3 Kruppel-like factor 3 (basic)
KREMEN2 kringle containing transmembrane protein 2
KRT13 keratin 13, type I
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCOLN3 mucolipin 3
MDM4 MDM4, p53 regulator
METTL8 methyltransferase like 8
MITF microphthalmia-associated transcription factor
MRPL41 mitochondrial ribosomal protein L41
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MX1 MX dynamin-like GTPase 1
NARFL nuclear prelamin A recognition factor-like
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
PAIP2B poly(A) binding protein interacting protein 2B
PDLIM2 PDZ and LIM domain 2 (mystique)
PHEX phosphate regulating endopeptidase homolog, X-linked
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRPH peripherin
QSER1 glutamine and serine rich 1
RABL6 RAB, member RAS oncogene family-like 6
RASAL1 RAS protein activator like 1 (GAP1 like)
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMA4 glucuronidase, beta pseudogene
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SP1 Sp1 transcription factor
SULT4A1 sulfotransferase family 4A, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TARP TCR gamma alternate reading frame protein
TBL1Y transducin (beta)-like 1, Y-linked
THBS3 thrombospondin 3
THRB thyroid hormone receptor, beta
TMC5 transmembrane channel-like 5
TMEM45A transmembrane protein 45A
TRAIP TRAF interacting protein
TUBA3C tubulin, alpha 3c
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZNF329 zinc finger protein 329
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516
ZNF532 zinc finger protein 532
ZNF665 zinc finger protein 665