Prestwick-1082-7267 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the Prestwick-1082-7267 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ARID1A AT rich interactive domain 1A (SWI-like)
ATF6B activating transcription factor 6 beta
BAIAP2 BAI1-associated protein 2
BCR breakpoint cluster region
BTN3A1 butyrophilin, subfamily 3, member A1
C1ORF116 chromosome 1 open reading frame 116
C9ORF156 chromosome 9 open reading frame 156
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CDC25C cell division cycle 25C
CEP112 centrosomal protein 112kDa
COX4I1 cytochrome c oxidase subunit IV isoform 1
CREB5 cAMP responsive element binding protein 5
CSRNP3 cysteine-serine-rich nuclear protein 3
CTSO cathepsin O
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DOCK5 dedicator of cytokinesis 5
DUSP1 dual specificity phosphatase 1
EFNB2 ephrin-B2
ELL elongation factor RNA polymerase II
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERCC1 excision repair cross-complementation group 1
FAM131B family with sequence similarity 131, member B
FEM1B fem-1 homolog b (C. elegans)
FKBP8 FK506 binding protein 8, 38kDa
FOXN3 forkhead box N3
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GABARAPL1 GABA(A) receptor-associated protein like 1
GNL1 guanine nucleotide binding protein-like 1
GOLGA2 golgin A2
GOLGA8A golgin A8 family, member A
HEATR6 HEAT repeat containing 6
HES2 hes family bHLH transcription factor 2
HIST1H2BN histone cluster 1, H2bn
HMOX1 heme oxygenase 1
HOXB7 homeobox B7
HPS4 Hermansky-Pudlak syndrome 4
IRS2 insulin receptor substrate 2
JADE2 jade family PHD finger 2
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAOA monoamine oxidase A
MAPK3 mitogen-activated protein kinase 3
MED25 mediator complex subunit 25
MID2 midline 2
MTUS1 microtubule associated tumor suppressor 1
MXD4 MAX dimerization protein 4
MYH15 myosin, heavy chain 15
NAV2 neuron navigator 2
NEBL nebulette
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NNMT nicotinamide N-methyltransferase
NOV nephroblastoma overexpressed
NRXN3 neurexin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARM1 prostate androgen-regulated mucin-like protein 1
PAX9 paired box 9
PDE4D phosphodiesterase 4D, cAMP-specific
PER1 period circadian clock 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCH1 phospholipase C, eta 1
PNPLA4 patatin-like phospholipase domain containing 4
RAP1GAP2 RAP1 GTPase activating protein 2
RGS17 regulator of G-protein signaling 17
RHOQ ras homolog family member Q
RNF146 ring finger protein 146
ROR1 receptor tyrosine kinase-like orphan receptor 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERTAD3 SERTA domain containing 3
SETD6 SET domain containing 6
SLC22A14 solute carrier family 22, member 14
SLC38A7 solute carrier family 38, member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG6 SMG6 nonsense mediated mRNA decay factor
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STS steroid sulfatase (microsomal), isozyme S
STX7 syntaxin 7
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP10 t-complex 10
THBS1 thrombospondin 1
TJAP1 tight junction associated protein 1 (peripheral)
TMCC1 transmembrane and coiled-coil domain family 1
TNIK TRAF2 and NCK interacting kinase
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPAN1 tetraspanin 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TXNRD3 thioredoxin reductase 3
UBOX5 U-box domain containing 5
UNC45A unc-45 homolog A (C. elegans)
VCAN versican
ZC3H12A zinc finger CCCH-type containing 12A
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF219 zinc finger protein 219
ZNF224 zinc finger protein 224
ZNF500 zinc finger protein 500
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
AATF apoptosis antagonizing transcription factor
ABHD8 abhydrolase domain containing 8
ANKFY1 ankyrin repeat and FYVE domain containing 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BTBD7 BTB (POZ) domain containing 7
C17ORF80 chromosome 17 open reading frame 80
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CAPN5 calpain 5
CCRL2 chemokine (C-C motif) receptor-like 2
CEP72 centrosomal protein 72kDa
CEP97 centrosomal protein 97kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN14 claudin 14
CLDN15 claudin 15
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COLGALT2 collagen beta(1-O)galactosyltransferase 2
COPS7B COP9 signalosome subunit 7B
CRYBB2P1 crystallin, beta B2 pseudogene 1
CUL9 cullin 9
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHRS3 dehydrogenase/reductase (SDR family) member 3
ECM1 extracellular matrix protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA4 ephrin-A4
EGLN1 egl-9 family hypoxia-inducible factor 1
EPHA4 EPH receptor A4
ERI3 ERI1 exoribonuclease family member 3
FGGY FGGY carbohydrate kinase domain containing
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HDAC9 histone deacetylase 9
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HIST1H1E histone cluster 1, H1e
HIST1H2AI histone cluster 1, H2ai
HIST1H3B histone cluster 1, H3b
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INSIG2 insulin induced gene 2
JAM3 junctional adhesion molecule 3
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIZ kizuna centrosomal protein
LPAR3 lysophosphatidic acid receptor 3
MEIS1 Meis homeobox 1
MFSD12 major facilitator superfamily domain containing 12
MITF microphthalmia-associated transcription factor
MXRA8 matrix-remodelling associated 8
NAG18 NAG18 mRNA
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NPR3 natriuretic peptide receptor 3
NTSR1 neurotensin receptor 1 (high affinity)
OLFML2A olfactomedin-like 2A
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPL periplakin
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKX protein kinase, X-linked
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STBD1 starch binding domain 1
STX17 syntaxin 17
STX5 syntaxin 5
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYTL2 synaptotagmin-like 2
TESPA1 thymocyte expressed, positive selection associated 1
TMEM121 transmembrane protein 121
TMEM2 transmembrane protein 2
TMEM57 transmembrane protein 57
TNS2 tensin 2
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TUBA3C tubulin, alpha 3c
TULP4 tubby like protein 4
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
XAB2 XPA binding protein 2
ZFYVE16 zinc finger, FYVE domain containing 16
ZMAT5 zinc finger, matrin-type 5
ZNF107 zinc finger protein 107
ZNF177 zinc finger protein 177
ZNF33B zinc finger protein 33B
ZNF385D zinc finger protein 385D
ZNF551 zinc finger protein 551
ZNF813 zinc finger protein 813
ZNF816 zinc finger protein 816