Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D054218
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Genes

143 genes/proteins associated with the disease Precursor T-Cell Lymphoblastic Leukemia-Lymphoma from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
RPL10 ribosomal protein L10 2.88009
IL7R interleukin 7 receptor 2.88009
RPL5 ribosomal protein L5 2.88009
CNOT3 CCR4-NOT transcription complex, subunit 3 2.88009
MYB v-myb avian myeloblastosis viral oncogene homolog 2.88009
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 2.88009
TAL1 T-cell acute lymphocytic leukemia 1 2.88009
PHF6 PHD finger protein 6 2.88009
LMO2 LIM domain only 2 (rhombotin-like 1) 2.88009
LMO1 LIM domain only 1 (rhombotin 1) 2.88009
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.88009
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 2.88009
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.88009
NOTCH1 notch 1 2.88009
PTPN2 protein tyrosine phosphatase, non-receptor type 2 2.88009
TLX1 T-cell leukemia homeobox 1 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.72384
ERBB2 erb-b2 receptor tyrosine kinase 2 1.68676
GSTM1 glutathione S-transferase mu 1 1.66425
BCL2L1 BCL2-like 1 1.56214
FAS Fas cell surface death receptor 1.54937
TYMS thymidylate synthetase 1.5382
BBC3 BCL2 binding component 3 1.50018
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.48736
VCAM1 vascular cell adhesion molecule 1 1.47167
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.46961
F3 coagulation factor III (thromboplastin, tissue factor) 1.46015
PARP1 poly (ADP-ribose) polymerase 1 1.4559
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.44899
BAX BCL2-associated X protein 1.42616
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.4164
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.41451
NQO1 NAD(P)H dehydrogenase, quinone 1 1.40623
PPARD peroxisome proliferator-activated receptor delta 1.39086
BCL2 B-cell CLL/lymphoma 2 1.37561
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.36332
NPPB natriuretic peptide B 1.36161
TP53 tumor protein p53 1.34459
IFNG interferon, gamma 1.33022
IL2 interleukin 2 1.32488
TGFB1 transforming growth factor, beta 1 1.29287
FOXO1 forkhead box O1 1.29194
IL4 interleukin 4 1.2895
IGFBP3 insulin-like growth factor binding protein 3 1.28119
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.27875
FKBP5 FK506 binding protein 5 1.26669
VEGFA vascular endothelial growth factor A 1.26267
LMCD1 LIM and cysteine-rich domains 1 1.26205
IGFBP5 insulin-like growth factor binding protein 5 1.25494
PLAT plasminogen activator, tissue 1.25121
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.24905
C1QA complement component 1, q subcomponent, A chain 1.24905
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.24874
TFPI2 tissue factor pathway inhibitor 2 1.24591
FASLG Fas ligand (TNF superfamily, member 6) 1.24024
BUB3 BUB3 mitotic checkpoint protein 1.2393
MCL1 myeloid cell leukemia 1 1.23648
THBS1 thrombospondin 1 1.22916
TNF tumor necrosis factor 1.22727
IL6 interleukin 6 1.22112
BIRC2 baculoviral IAP repeat containing 2 1.21887
MUCL1 mucin-like 1 1.21823
GCLC glutamate-cysteine ligase, catalytic subunit 1.21823
RRM2 ribonucleotide reductase M2 1.2137
CCND3 cyclin D3 1.21043
KLF2 Kruppel-like factor 2 1.20751
DMD dystrophin 1.20751
PRC1 protein regulator of cytokinesis 1 1.20751
GPX3 glutathione peroxidase 3 1.20361
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.20196
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.19246
CDK2 cyclin-dependent kinase 2 1.18718
ATF3 activating transcription factor 3 1.18293
CSTA cystatin A (stefin A) 1.17497
PMP22 peripheral myelin protein 22 1.167
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.16104
F2 coagulation factor II (thrombin) 1.15122
GBP1 guanylate binding protein 1, interferon-inducible 1.1485
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.1461
SPP1 secreted phosphoprotein 1 1.14302
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.14064
TGFBR3 transforming growth factor, beta receptor III 1.14064
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.1403
SOD2 superoxide dismutase 2, mitochondrial 1.13997
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.12391
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.12323
MKI67 marker of proliferation Ki-67 1.12219
CTGF connective tissue growth factor 1.11843
PRLR prolactin receptor 1.11741
IL5 interleukin 5 1.1122
TOP2A topoisomerase (DNA) II alpha 170kDa 1.1122
CTSL cathepsin L 1.11151
BAD BCL2-associated agonist of cell death 1.11081
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.10942
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.10631
RB1 retinoblastoma 1 1.10596
NPPA natriuretic peptide A 1.10388
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.08904
CES3 carboxylesterase 3 1.08372
CCL2 chemokine (C-C motif) ligand 2 1.08196
EPO erythropoietin 1.0784
CD69 CD69 molecule 1.07732
GSTA1 glutathione S-transferase alpha 1 1.07732
DUSP10 dual specificity phosphatase 10 1.07411
CXCL10 chemokine (C-X-C motif) ligand 10 1.07269
APOB apolipoprotein B 1.06987
CCNE1 cyclin E1 1.06844
MAP2K3 mitogen-activated protein kinase kinase 3 1.06844
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.06808
MPO myeloperoxidase 1.06625
IGF1 insulin-like growth factor 1 (somatomedin C) 1.06442
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.06333
EGF epidermal growth factor 1.06188
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.06152
KRT8 keratin 8, type II 1.06008
CCNA2 cyclin A2 1.05972
DDIT3 DNA-damage-inducible transcript 3 1.05793
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.05648
EDNRB endothelin receptor type B 1.05163
HSPA1B heat shock 70kDa protein 1B 1.05015
IL1B interleukin 1, beta 1.04904
DUSP4 dual specificity phosphatase 4 1.04794
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.04684
MAOA monoamine oxidase A 1.04684
DOK4 docking protein 4 1.04647
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.04276
LBP lipopolysaccharide binding protein 1.03976
SESN1 sestrin 1 1.03159
BTG2 BTG family, member 2 1.03009
MGMT O-6-methylguanine-DNA methyltransferase 1.03009
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.02708
UGCG UDP-glucose ceramide glucosyltransferase 1.0241
CCL5 chemokine (C-C motif) ligand 5 1.0241
TF transferrin 1.02262
CD14 CD14 molecule 1.02262
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.02225
MMP3 matrix metallopeptidase 3 1.01701
FYN FYN proto-oncogene, Src family tyrosine kinase 1.01663
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.01399
GSK3B glycogen synthase kinase 3 beta 1.01286
HAMP hepcidin antimicrobial peptide 1.01212
ERBB3 erb-b2 receptor tyrosine kinase 3 1.01174
CD68 CD68 molecule 1.01174