Post-translational protein modification Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
Description The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. (Gene Ontology, GO_0043687)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-597592
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Genes

278 proteins participating in the Post-translational protein modification pathway from the Reactome Pathways dataset.

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADAMTSL1 ADAMTS-like 1
ADAMTSL2 ADAMTS-like 2
ADAMTSL3 ADAMTS-like 3
ADAMTSL4 ADAMTS-like 4
ADAMTSL5 ADAMTS-like 5
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALG10 ALG10, alpha-1,2-glucosyltransferase
ALG10B ALG10B, alpha-1,2-glucosyltransferase
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALG6 ALG6, alpha-1,3-glucosyltransferase
ALG8 ALG8, alpha-1,3-glucosyltransferase
ALG9 ALG9, alpha-1,2-mannosyltransferase
ARSA arylsulfatase A
ARSB arylsulfatase B
ARSD arylsulfatase D
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ARSF arylsulfatase F
ARSG arylsulfatase G
ARSH arylsulfatase family, member H
ARSI arylsulfatase family, member I
ARSJ arylsulfatase family, member J
ARSK arylsulfatase family, member K
B3GALTL beta 1,3-galactosyltransferase-like
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1GALT1C1 C1GALT1-specific chaperone 1
CALR calreticulin
CANX calnexin
CFP complement factor properdin
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CTSA cathepsin A
DAD1 defender against cell death 1
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DHDDS dehydrodolichyl diphosphate synthase
DHPS deoxyhypusine synthase
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DOHH deoxyhypusine hydroxylase/monooxygenase
DOLK dolichol kinase
DOLPP1 dolichyldiphosphatase 1
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPH1 diphthamide biosynthesis 1
DPH2 DPH2 homolog (S. cerevisiae)
DPH3 diphthamide biosynthesis 3
DPH5 diphthamide biosynthesis 5
DPH6 diphthamine biosynthesis 6
DPH7 diphthamide biosynthesis 7
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EEF2 eukaryotic translation elongation factor 2
EIF5A eukaryotic translation initiation factor 5A
EIF5A2 eukaryotic translation initiation factor 5A2
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F9 coagulation factor IX
FURIN furin (paired basic amino acid cleaving enzyme)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15
GALNT16 polypeptide N-acetylgalactosaminyltransferase 16
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GALNT9 polypeptide N-acetylgalactosaminyltransferase 9
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6
GANAB glucosidase, alpha; neutral AB
GAS6 growth arrest-specific 6
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GCNT6 glucosaminyl (N-acetyl) transferase 6
GCNT7 glucosaminyl (N-acetyl) transferase family member 7
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GGCX gamma-glutamyl carboxylase
GLB1 galactosidase, beta 1
GMPPA GDP-mannose pyrophosphorylase A
GMPPB GDP-mannose pyrophosphorylase B
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GPAA1 glycosylphosphatidylinositol anchor attachment 1
LMAN1 lectin, mannose-binding, 1
MAGT1 magnesium transporter 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN1A2 mannosidase, alpha, class 1A, member 2
MAN1B1 mannosidase, alpha, class 1B, member 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MANEA mannosidase, endo-alpha
MCFD2 multiple coagulation factor deficiency 2
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGAT4C MGAT4 family, member C
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MLEC malectin
MOGS mannosyl-oligosaccharide glucosidase
MPDU1 mannose-P-dolichol utilization defect 1
MPI mannose phosphate isomerase
MUC1 mucin 1, cell surface associated
MUC12 mucin 12, cell surface associated
MUC13 mucin 13, cell surface associated
MUC15 mucin 15, cell surface associated
MUC16 mucin 16, cell surface associated
MUC17 mucin 17, cell surface associated
MUC19 mucin 19, oligomeric
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC20 mucin 20, cell surface associated
MUC21 mucin 21, cell surface associated
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MUCL1 mucin-like 1
MVD mevalonate (diphospho) decarboxylase
NANP N-acetylneuraminic acid phosphatase
NANS N-acetylneuraminic acid synthase
NEU1 sialidase 1 (lysosomal sialidase)
NEU2 sialidase 2 (cytosolic sialidase)
NEU3 sialidase 3 (membrane sialidase)
NEU4 sialidase 4
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
PDIA3 protein disulfide isomerase family A, member 3
PGAP1 post-GPI attachment to proteins 1
PGM3 phosphoglucomutase 3
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGM phosphatidylinositol glycan anchor biosynthesis, class M
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIGW phosphatidylinositol glycan anchor biosynthesis, class W
PIGX phosphatidylinositol glycan anchor biosynthesis, class X
PLAUR plasminogen activator, urokinase receptor
PMM1 phosphomannomutase 1
PMM2 phosphomannomutase 2
POFUT2 protein O-fucosyltransferase 2
PREB prolactin regulatory element binding
PRKCSH protein kinase C substrate 80K-H
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PROZ protein Z, vitamin K-dependent plasma glycoprotein
RFT1 RFT1 homolog (S. cerevisiae)
RPN1 ribophorin I
RPN2 ribophorin II
SAE1 SUMO1 activating enzyme subunit 1
SAR1B secretion associated, Ras related GTPase 1B
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SENP1 SUMO1/sentrin specific peptidase 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SENP5 SUMO1/sentrin specific peptidase 5
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
SSPO SCO-spondin
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STS steroid sulfatase (microsomal), isozyme S
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
SUMF1 sulfatase modifying factor 1
SUMF2 sulfatase modifying factor 2
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THSD1 thrombospondin, type I, domain containing 1
THSD4 thrombospondin, type I, domain containing 4
THSD7A thrombospondin, type I, domain containing 7A
THSD7B thrombospondin, type I, domain containing 7B
TUSC3 tumor suppressor candidate 3
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2I ubiquitin-conjugating enzyme E2I
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VKORC1 vitamin K epoxide reductase complex, subunit 1
WBSCR17 Williams-Beuren syndrome chromosome region 17