Polyps Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Discrete abnormal tissue masses that protrude into the lumen of the DIGESTIVE TRACT or the RESPIRATORY TRACT. Polyps can be spheroidal, hemispheroidal, or irregular mound-shaped structures attached to the MUCOUS MEMBRANE of the lumen wall either by a stalk, pedunculus, or by a broad base.|A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations. -- 2004|A usually exophytic mass attached to the underlying tissue by a broad base or a thin stalk. Polyps can be neoplastic or non-neoplastic. Neoplastic polyps usually represent proliferations of the epithelium, and are commonly seen in the gastrointestinal tract. Polyps of the gastrointestinal tract are often called adenomas, are associated with dysplasia, and may eventually transform into carcinomas. Non-neoplastic polyps may be inflammatory, degenerative, or the result of malformations. (Experimental Factor Ontology, EFO_0000662)
Similar Terms
Downloads & Tools

Genes

47 genes associated with the Polyps phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
APC adenomatous polyposis coli
ARMS2 age-related maculopathy susceptibility 2
BMPR1A bone morphogenetic protein receptor, type IA
BRAF B-Raf proto-oncogene, serine/threonine kinase
C2 complement component 2
C3 complement component 3
C5 complement component 5
C7 complement component 7
CETP cholesteryl ester transfer protein, plasma
CFB complement factor B
CFH complement factor H
CFI complement factor I
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
ERCC6 excision repair cross-complementation group 6
FBLN5 fibulin 5
HMCN1 hemicentin 1
HTRA1 HtrA serine peptidase 1
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
KDR kinase insert domain receptor
LOC389641 uncharacterized LOC389641
MUTYH mutY homolog
NOA1 nitric oxide associated 1
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
REST RE1-silencing transcription factor
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMAD4 SMAD family member 4
SOD1 superoxide dismutase 1, soluble
TIMP3 TIMP metallopeptidase inhibitor 3
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor