Polycystic Ovary Syndrome_Adipose tissue_GSE5090 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE5090
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Genes

600 genes differentially expressed during Polycystic Ovary Syndrome_Adipose tissue_GSE5090 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
EXT2 exostosin glycosyltransferase 2 4.05409
CSE1L CSE1 chromosome segregation 1-like (yeast) 3.41563
FBXL5 F-box and leucine-rich repeat protein 5 3.39703
TMBIM4 transmembrane BAX inhibitor motif containing 4 2.99404
PPP1R9A protein phosphatase 1, regulatory subunit 9A 2.93835
UXS1 UDP-glucuronate decarboxylase 1 2.78716
PBX2 pre-B-cell leukemia homeobox 2 2.74868
SCAPER S-phase cyclin A-associated protein in the ER 2.65815
HRAS Harvey rat sarcoma viral oncogene homolog 2.60585
MINA MYC induced nuclear antigen 2.57692
NPM3 nucleophosmin/nucleoplasmin 3 2.54803
EEA1 early endosome antigen 1 2.51829
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 2.49463
SERINC3 serine incorporator 3 2.45395
IFT57 intraflagellar transport 57 2.44089
ZCCHC6 zinc finger, CCHC domain containing 6 2.4223
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 2.37522
GTPBP6 GTP binding protein 6 (putative) 2.37452
LASP1 LIM and SH3 protein 1 2.3703
C2ORF49 chromosome 2 open reading frame 49 2.35985
DICER1 dicer 1, ribonuclease type III 2.35543
EIF5B eukaryotic translation initiation factor 5B 2.34106
CHD4 chromodomain helicase DNA binding protein 4 2.33934
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) 2.33275
SKP1 S-phase kinase-associated protein 1 2.32045
ADAM17 ADAM metallopeptidase domain 17 2.31102
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.30353
PXK PX domain containing serine/threonine kinase 2.30172
TROVE2 TROVE domain family, member 2 2.27406
SCPEP1 serine carboxypeptidase 1 2.25015
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.19988
RPS19 ribosomal protein S19 2.15553
SPEN spen family transcriptional repressor 2.15382
MXRA7 matrix-remodelling associated 7 2.14439
KTN1 kinectin 1 (kinesin receptor) 2.14161
TCTA T-cell leukemia translocation altered 2.12689
CKAP5 cytoskeleton associated protein 5 2.08021
RRAGC Ras-related GTP binding C 2.07169
RASA1 RAS p21 protein activator (GTPase activating protein) 1 2.05591
CYB561 cytochrome b561 2.05435
MECOM MDS1 and EVI1 complex locus 2.04224
SETX senataxin 2.03745
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.03594
PHACTR2 phosphatase and actin regulator 2 2.01401
WBP1L WW domain binding protein 1-like 2.00956
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.00427
MYO6 myosin VI 1.99482
CCND2 cyclin D2 1.99399
SMNDC1 survival motor neuron domain containing 1 1.99348
SCLY selenocysteine lyase 1.98695
CCDC64B coiled-coil domain containing 64B 1.96301
B2M beta-2-microglobulin 1.94558
NME5 NME/NM23 family member 5 1.94314
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.90921
PCBP2 poly(rC) binding protein 2 1.9019
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) 1.90085
RFC2 replication factor C (activator 1) 2, 40kDa 1.8983
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) 1.89164
FERMT2 fermitin family member 2 1.88848
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 1.88461
STAP2 signal transducing adaptor family member 2 1.88248
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 1.88122
ZCCHC24 zinc finger, CCHC domain containing 24 1.87495
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 1.87269
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.8718
CHRDL1 chordin-like 1 1.86918
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.86489
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 1.86381
LEPROT leptin receptor overlapping transcript 1.86372
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 1.85914
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 1.85061
ZDHHC3 zinc finger, DHHC-type containing 3 1.84869
UBXN7 UBX domain protein 7 1.84548
EIF3A eukaryotic translation initiation factor 3, subunit A 1.84129
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.8335
KIAA0196 KIAA0196 1.82685
KIAA0232 KIAA0232 1.81402
SYNC syncoilin, intermediate filament protein 1.81375
DNAJC25-GNG10 DNAJC25-GNG10 readthrough 1.81072
CTR9 CTR9, Paf1/RNA polymerase II complex component 1.80768
PLA2G12A phospholipase A2, group XIIA 1.79894
SCAF11 SR-related CTD-associated factor 11 1.78813
NCKAP1 NCK-associated protein 1 1.78633
NAGA N-acetylgalactosaminidase, alpha- 1.78491
MTDH metadherin 1.78461
FNDC3B fibronectin type III domain containing 3B 1.77641
TULP4 tubby like protein 4 1.77416
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 1.77288
KRT10 keratin 10, type I 1.77187
USP8 ubiquitin specific peptidase 8 1.76668
MSRA methionine sulfoxide reductase A 1.76494
GSTM1 glutathione S-transferase mu 1 1.76172
PSENEN presenilin enhancer gamma secretase subunit 1.75895
MAP4 microtubule-associated protein 4 1.7553
LBR lamin B receptor 1.7477
PPP1R7 protein phosphatase 1, regulatory subunit 7 1.7465
CTBP1 C-terminal binding protein 1 1.74608
SETD3 SET domain containing 3 1.74557
MSN moesin 1.7393
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.73573
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.73396
ANGPTL2 angiopoietin-like 2 1.73235
N4BP1 NEDD4 binding protein 1 1.72949
SDCBP syndecan binding protein (syntenin) 1.72829
BAG5 BCL2-associated athanogene 5 1.72101
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 1.71935
USP33 ubiquitin specific peptidase 33 1.71792
RAB9A RAB9A, member RAS oncogene family 1.7179
RPIA ribose 5-phosphate isomerase A 1.71738
MAEA macrophage erythroblast attacher 1.71478
DACH1 dachshund family transcription factor 1 1.71391
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 1.70858
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.69074
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 1.68832
DYNLL1 dynein, light chain, LC8-type 1 1.68793
PVRIG poliovirus receptor related immunoglobulin domain containing 1.68045
PTPN6 protein tyrosine phosphatase, non-receptor type 6 1.67138
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.67093
IL6ST interleukin 6 signal transducer 1.6674
KLHDC3 kelch domain containing 3 1.66699
KIF1BP KIF1 binding protein 1.66602
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 1.66537
GSTM2 glutathione S-transferase mu 2 (muscle) 1.66443
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 1.66151
ACAA1 acetyl-CoA acyltransferase 1 1.65804
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 1.65178
CREB3L2 cAMP responsive element binding protein 3-like 2 1.65149
LMBR1L limb development membrane protein 1-like 1.65009
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 1.64254
PTGES2 prostaglandin E synthase 2 1.64229
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 1.63854
SCRN1 secernin 1 1.63669
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.63463
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.63454
SP140 SP140 nuclear body protein 1.62863
CCDC91 coiled-coil domain containing 91 1.62634
TMEM183A transmembrane protein 183A 1.62294
ANKRD46 ankyrin repeat domain 46 1.61925
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.6047
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.60292
C8ORF33 chromosome 8 open reading frame 33 1.60223
BAHD1 bromo adjacent homology domain containing 1 1.59845
WRB tryptophan rich basic protein 1.59726
CAV1 caveolin 1, caveolae protein, 22kDa 1.59715
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 1.59487
STRAP serine/threonine kinase receptor associated protein 1.58838
KRAS Kirsten rat sarcoma viral oncogene homolog 1.58709
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.582
TUFT1 tuftelin 1 1.57568
NR1D2 nuclear receptor subfamily 1, group D, member 2 1.57276
EPRS glutamyl-prolyl-tRNA synthetase 1.56897
CSTB cystatin B (stefin B) 1.5689
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.56809
SESN1 sestrin 1 1.56435
UNC13B unc-13 homolog B (C. elegans) 1.56298
PPARD peroxisome proliferator-activated receptor delta 1.56285
CHMP1A charged multivesicular body protein 1A 1.56133
VLDLR very low density lipoprotein receptor 1.55666
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 1.55621
TRIM16 tripartite motif containing 16 1.55376
PAIP1 poly(A) binding protein interacting protein 1 1.55214
CRLF3 cytokine receptor-like factor 3 1.55072
PHKB phosphorylase kinase, beta 1.55072
MDH1 malate dehydrogenase 1, NAD (soluble) 1.54503
PHKG2 phosphorylase kinase, gamma 2 (testis) 1.54448
AASS aminoadipate-semialdehyde synthase 1.54381
JTB jumping translocation breakpoint 1.54288
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.54063
TOB1 transducer of ERBB2, 1 1.5396
MXD4 MAX dimerization protein 4 1.53821
UBN1 ubinuclein 1 1.53595
ZNF136 zinc finger protein 136 1.5348
FAM63A family with sequence similarity 63, member A 1.53351
NFE2L1 nuclear factor, erythroid 2-like 1 1.53119
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 1.53028
GOLGA5 golgin A5 1.52887
CDKN2AIP CDKN2A interacting protein 1.52675
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 1.52394
MAP1B microtubule-associated protein 1B 1.51955
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 1.51925
CHP1 calcineurin-like EF-hand protein 1 1.51877
ARHGAP10 Rho GTPase activating protein 10 1.51699
DYNLRB1 dynein, light chain, roadblock-type 1 1.51354
TMEM140 transmembrane protein 140 1.51271
VEZF1 vascular endothelial zinc finger 1 1.51157
WBSCR22 Williams Beuren syndrome chromosome region 22 1.51137
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 1.51127
STAMBP STAM binding protein 1.50766
THOC2 THO complex 2 1.50754
COX7BP1 cytochrome c oxidase subunit VIIb pseudogene 1 1.50463
CHD8 chromodomain helicase DNA binding protein 8 1.50333
TNPO1 transportin 1 1.50182
PEX3 peroxisomal biogenesis factor 3 1.5016
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 1.50156
ZNF148 zinc finger protein 148 1.49786
MAN2A2 mannosidase, alpha, class 2A, member 2 1.49744
ANXA11 annexin A11 1.4937
GTF2IRD1 GTF2I repeat domain containing 1 1.49125
AKTIP AKT interacting protein 1.49114
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 1.48847
SATB1 SATB homeobox 1 1.48635
GRB2 growth factor receptor-bound protein 2 1.48589
TMEM184B transmembrane protein 184B 1.48325
WRN Werner syndrome, RecQ helicase-like 1.48147
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.4809
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 1.4788
PCSK5 proprotein convertase subtilisin/kexin type 5 1.4778
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) 1.47748
RPP30 ribonuclease P/MRP 30kDa subunit 1.47257
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 1.4718
STARD13 StAR-related lipid transfer (START) domain containing 13 1.47018
CDC14B cell division cycle 14B 1.4673
LEMD3 LEM domain containing 3 1.46703
IFNGR1 interferon gamma receptor 1 1.46575
TPK1 thiamin pyrophosphokinase 1 1.46509
SURF1 surfeit 1 1.46442
PARG poly (ADP-ribose) glycohydrolase 1.46337
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 1.46029
MRPS6 mitochondrial ribosomal protein S6 1.4595
MTMR6 myotubularin related protein 6 1.45803
COPS8 COP9 signalosome subunit 8 1.45405
SNRK SNF related kinase 1.45282
GLYATL2 glycine-N-acyltransferase-like 2 1.45115
LYPLA2 lysophospholipase II 1.45091
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 1.44832
HMGB1 high mobility group box 1 1.44805
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 1.44269
TRIM66 tripartite motif containing 66 1.44096
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 1.43906
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.43231
ERBB4 erb-b2 receptor tyrosine kinase 4 1.4319
SLC39A6 solute carrier family 39 (zinc transporter), member 6 1.42841
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 1.42833
HIPK1 homeodomain interacting protein kinase 1 1.42532
PAPD5 PAP associated domain containing 5 1.42427
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.42293
TMEM5 transmembrane protein 5 1.42183
ANXA7 annexin A7 1.42162
FKBP9 FK506 binding protein 9, 63 kDa 1.42124
TMSB10 thymosin beta 10 1.42118
ALG6 ALG6, alpha-1,3-glucosyltransferase 1.41785
RAB14 RAB14, member RAS oncogene family 1.41585
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.41466
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 1.41356
RPL27A ribosomal protein L27a 1.41318
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 1.41287
S100A10 S100 calcium binding protein A10 1.41187
CLCN3 chloride channel, voltage-sensitive 3 1.4118
KLK1 kallikrein 1 1.41157
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.41106
DAXX death-domain associated protein 1.4104
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 1.40917
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.40649
ADGRA3 adhesion G protein-coupled receptor A3 1.40445
PRR13 proline rich 13 1.40278
TUBA1A tubulin, alpha 1a 1.40074
RPS13 ribosomal protein S13 1.39312
MRPL24 mitochondrial ribosomal protein L24 1.39197
NUTF2 nuclear transport factor 2 1.39175
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 1.39138
ZNF329 zinc finger protein 329 1.39097
SMAD2 SMAD family member 2 1.38897
TPD52L1 tumor protein D52-like 1 1.38577
UBE2G2 ubiquitin-conjugating enzyme E2G 2 1.38539
RHOC ras homolog family member C 1.37652
SCAMP2 secretory carrier membrane protein 2 1.37179
CIAO1 cytosolic iron-sulfur assembly component 1 1.36831
RASA2 RAS p21 protein activator 2 1.36757
NF1 neurofibromin 1 1.36598
ESYT1 extended synaptotagmin-like protein 1 1.36345
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.36315
RBM22 RNA binding motif protein 22 1.36149
MTMR14 myotubularin related protein 14 1.35861
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 1.35755
TTC27 tetratricopeptide repeat domain 27 1.35656
SCNM1 sodium channel modifier 1 1.35395
GLB1L galactosidase, beta 1-like 1.35359
PON2 paraoxonase 2 1.35239
DDB1 damage-specific DNA binding protein 1, 127kDa 1.35189
CMC4 C-x(9)-C motif containing 4 1.35078
DNASE2 deoxyribonuclease II, lysosomal 1.34836
OXSR1 oxidative stress responsive 1 1.34346
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 1.34133
CETN2 centrin, EF-hand protein, 2 1.34064
ZCCHC2 zinc finger, CCHC domain containing 2 1.33969
CLU clusterin 1.33951
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.33918
TTC17 tetratricopeptide repeat domain 17 1.33913
PTPRG protein tyrosine phosphatase, receptor type, G 1.33796
SCRIB scribbled planar cell polarity protein 1.33752
SLMO2 slowmo homolog 2 (Drosophila) 1.33749
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.33678
LYPLA1 lysophospholipase I 1.33572
TMF1 TATA element modulatory factor 1 1.33435
ACBD3 acyl-CoA binding domain containing 3 1.3325
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 1.33176
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.33086
PRIM1 primase, DNA, polypeptide 1 (49kDa) 1.33085
SAP30 Sin3A-associated protein, 30kDa 1.32845
RNF121 ring finger protein 121 1.32682

decreased expression

Symbol Name Standardized Value
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) -3.89468
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -3.64469
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -3.17592
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -3.15312
TMEM248 transmembrane protein 248 -3.1445
APP amyloid beta (A4) precursor protein -2.9734
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -2.94763
SDC2 syndecan 2 -2.89319
NONO non-POU domain containing, octamer-binding -2.6867
MED17 mediator complex subunit 17 -2.67856
PSEN1 presenilin 1 -2.6044
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -2.59396
TRIM13 tripartite motif containing 13 -2.57514
TOX4 TOX high mobility group box family member 4 -2.54103
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -2.45834
PDE5A phosphodiesterase 5A, cGMP-specific -2.44481
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -2.44266
PURA purine-rich element binding protein A -2.41612
MEOX1 mesenchyme homeobox 1 -2.41214
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -2.38377
ADORA1 adenosine A1 receptor -2.36996
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -2.36423
NUP214 nucleoporin 214kDa -2.3572
MFAP4 microfibrillar-associated protein 4 -2.34893
TMEM87A transmembrane protein 87A -2.34318
CBFB core-binding factor, beta subunit -2.34043
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit -2.30384
RPP14 ribonuclease P/MRP 14kDa subunit -2.29922
LAMP1 lysosomal-associated membrane protein 1 -2.28823
COG5 component of oligomeric golgi complex 5 -2.28373
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -2.28239
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -2.27523
THRA thyroid hormone receptor, alpha -2.27433
CARS cysteinyl-tRNA synthetase -2.27071
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.26585
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.26501
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -2.26378
HELZ helicase with zinc finger -2.24674
FHOD1 formin homology 2 domain containing 1 -2.24423
DCAF7 DDB1 and CUL4 associated factor 7 -2.24219
RBM28 RNA binding motif protein 28 -2.23215
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.22125
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa -2.21335
GALC galactosylceramidase -2.20589
ZBTB5 zinc finger and BTB domain containing 5 -2.20335
MTMR9 myotubularin related protein 9 -2.18295
ASNSD1 asparagine synthetase domain containing 1 -2.17655
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.17207
AKT3 v-akt murine thymoma viral oncogene homolog 3 -2.1715
CXCL9 chemokine (C-X-C motif) ligand 9 -2.16793
ZMYM6 zinc finger, MYM-type 6 -2.15573
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.15216
FKBP1A FK506 binding protein 1A, 12kDa -2.1381
CNOT1 CCR4-NOT transcription complex, subunit 1 -2.13033
SERBP1 SERPINE1 mRNA binding protein 1 -2.12588
ZNF330 zinc finger protein 330 -2.12021
API5 apoptosis inhibitor 5 -2.11522
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.11227
DDIT3 DNA-damage-inducible transcript 3 -2.11037
EFNB1 ephrin-B1 -2.10668
TSPAN7 tetraspanin 7 -2.10182
CD40 CD40 molecule, TNF receptor superfamily member 5 -2.09699
DSTN destrin (actin depolymerizing factor) -2.09339
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -2.08522
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.08225
OCEL1 occludin/ELL domain containing 1 -2.07766
ARF1 ADP-ribosylation factor 1 -2.07113
RPS2 ribosomal protein S2 -2.06931
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.0645
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -2.06079
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.05258
NOTCH2 notch 2 -2.02965
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -2.02758
GCDH glutaryl-CoA dehydrogenase -2.02069
SEC16A SEC16 homolog A (S. cerevisiae) -2.01581
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 -2.01513
METTL4 methyltransferase like 4 -2.00413
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -2.00291
CCKBR cholecystokinin B receptor -2.00204
MRPS30 mitochondrial ribosomal protein S30 -2.00185
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -1.99327
METAP1 methionyl aminopeptidase 1 -1.98268
YY1 YY1 transcription factor -1.96734
RPS18 ribosomal protein S18 -1.95463
YIPF3 Yip1 domain family, member 3 -1.93216
PDIA3 protein disulfide isomerase family A, member 3 -1.92692
LAPTM4A lysosomal protein transmembrane 4 alpha -1.9227
THAP7 THAP domain containing 7 -1.9199
SRP72 signal recognition particle 72kDa -1.9095
ZC3H11A zinc finger CCCH-type containing 11A -1.90787
RGS17 regulator of G-protein signaling 17 -1.9056
ADO 2-aminoethanethiol (cysteamine) dioxygenase -1.9006
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -1.88638
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) -1.88455
FAM50A family with sequence similarity 50, member A -1.88126
SDF2 stromal cell-derived factor 2 -1.87682
TPT1 tumor protein, translationally-controlled 1 -1.8744
CADM1 cell adhesion molecule 1 -1.87305
HRG histidine-rich glycoprotein -1.87292
TLR4 toll-like receptor 4 -1.87225
ZNF207 zinc finger protein 207 -1.86563
BUD31 BUD31 homolog (S. cerevisiae) -1.86421
IMMT inner membrane protein, mitochondrial -1.86115
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -1.8588
ZNF710 zinc finger protein 710 -1.85661
PTGES prostaglandin E synthase -1.8466
GM2A GM2 ganglioside activator -1.84205
CDC37L1 cell division cycle 37-like 1 -1.84161
TSPAN12 tetraspanin 12 -1.84157
RANBP3 RAN binding protein 3 -1.83001
PLXNA1 plexin A1 -1.82633
MPP1 membrane protein, palmitoylated 1, 55kDa -1.80792
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -1.80705
MED9 mediator complex subunit 9 -1.79841
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 -1.79516
ATG2B autophagy related 2B -1.7889
CCDC130 coiled-coil domain containing 130 -1.78833
ZNF24 zinc finger protein 24 -1.77848
FBXO7 F-box protein 7 -1.7672
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -1.7637
NSUN3 NOP2/Sun domain family, member 3 -1.76111
ADCK2 aarF domain containing kinase 2 -1.76026
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -1.75687
DACT1 dishevelled-binding antagonist of beta-catenin 1 -1.75649
SIAH1 siah E3 ubiquitin protein ligase 1 -1.75611
GCHFR GTP cyclohydrolase I feedback regulator -1.75542
KCTD9 potassium channel tetramerization domain containing 9 -1.75224
RAB8A RAB8A, member RAS oncogene family -1.74343
RNF126P1 ring finger protein 126 pseudogene 1 -1.74094
SS18 synovial sarcoma translocation, chromosome 18 -1.73799
HAB1 B1 for mucin -1.73758
EMG1 EMG1 N1-specific pseudouridine methyltransferase -1.73672
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.73205
CSNK2A1 casein kinase 2, alpha 1 polypeptide -1.71835
C1ORF27 chromosome 1 open reading frame 27 -1.70947
NID1 nidogen 1 -1.7086
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -1.70789
TMEM131 transmembrane protein 131 -1.70518
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -1.69732
AKAP8L A kinase (PRKA) anchor protein 8-like -1.69409
SBF1 SET binding factor 1 -1.69033
MAPK13 mitogen-activated protein kinase 13 -1.6892
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -1.68608
CCHCR1 coiled-coil alpha-helical rod protein 1 -1.686
C9ORF40 chromosome 9 open reading frame 40 -1.6856
SREBF1 sterol regulatory element binding transcription factor 1 -1.68371
ERLIN1 ER lipid raft associated 1 -1.68054
AR androgen receptor -1.67657
NADK NAD kinase -1.67277
ARL8B ADP-ribosylation factor-like 8B -1.67269
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -1.67229
XPO7 exportin 7 -1.67223
TEX30 testis expressed 30 -1.67218
FAM49A family with sequence similarity 49, member A -1.66936
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.66561
DOCK9 dedicator of cytokinesis 9 -1.65779
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit -1.65727
BCL2L1 BCL2-like 1 -1.65497
DCTN5 dynactin 5 (p25) -1.65302
RALY RALY heterogeneous nuclear ribonucleoprotein -1.65127
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) -1.64496
SRSF1 serine/arginine-rich splicing factor 1 -1.64483
PDIA6 protein disulfide isomerase family A, member 6 -1.6442
ANAPC5 anaphase promoting complex subunit 5 -1.64253
MORC4 MORC family CW-type zinc finger 4 -1.63989
RAI2 retinoic acid induced 2 -1.6398
MARS methionyl-tRNA synthetase -1.63445
HLA-G major histocompatibility complex, class I, G -1.63191
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -1.6309
CCDC73 coiled-coil domain containing 73 -1.62908
HMOX2 heme oxygenase 2 -1.62485
IFITM3 interferon induced transmembrane protein 3 -1.61464
MFAP1 microfibrillar-associated protein 1 -1.61328
SAMD14 sterile alpha motif domain containing 14 -1.61184
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -1.61052
PANK2 pantothenate kinase 2 -1.60984
PRPF4B pre-mRNA processing factor 4B -1.60779
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.60772
CSRP2 cysteine and glycine-rich protein 2 -1.60575
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -1.60517
DAP death-associated protein -1.60392
INO80B INO80 complex subunit B -1.60382
FBLN1 fibulin 1 -1.6032
DRAM1 DNA-damage regulated autophagy modulator 1 -1.59789
CLTA clathrin, light chain A -1.59749
ARF3 ADP-ribosylation factor 3 -1.59526
ZNF195 zinc finger protein 195 -1.59483
TMEM63A transmembrane protein 63A -1.5929
RBM8A RNA binding motif protein 8A -1.58977
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -1.58147
DERL1 derlin 1 -1.57996
GALNS galactosamine (N-acetyl)-6-sulfatase -1.57383
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -1.57302
VWA8 von Willebrand factor A domain containing 8 -1.57129
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -1.56816
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) -1.56725
ASTN2 astrotactin 2 -1.56693
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -1.56541
TRIM24 tripartite motif containing 24 -1.56457
SSRP1 structure specific recognition protein 1 -1.56391
SOX15 SRY (sex determining region Y)-box 15 -1.55596
TRAF3 TNF receptor-associated factor 3 -1.55485
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) -1.55419
EML4 echinoderm microtubule associated protein like 4 -1.5531
SNF8 SNF8, ESCRT-II complex subunit -1.55167
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -1.54779
CXCL12 chemokine (C-X-C motif) ligand 12 -1.54718
FUBP1 far upstream element (FUSE) binding protein 1 -1.54591
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -1.54447
EMC7 ER membrane protein complex subunit 7 -1.53629
MPZL1 myelin protein zero-like 1 -1.53437
GOSR2 golgi SNAP receptor complex member 2 -1.53396
GTPBP3 GTP binding protein 3 (mitochondrial) -1.5324
HYOU1 hypoxia up-regulated 1 -1.52785
LTBP1 latent transforming growth factor beta binding protein 1 -1.5275
MTPAP mitochondrial poly(A) polymerase -1.52617
TMEM41B transmembrane protein 41B -1.5256
KIF2A kinesin heavy chain member 2A -1.52546
WDR78 WD repeat domain 78 -1.5233
CAB39 calcium binding protein 39 -1.52249
MAPK1 mitogen-activated protein kinase 1 -1.52149
RNF146 ring finger protein 146 -1.52102
FXN frataxin -1.52088
HAUS7 HAUS augmin-like complex, subunit 7 -1.52052
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -1.51795
SF3B5 splicing factor 3b, subunit 5, 10kDa -1.51791
DCTN4 dynactin 4 (p62) -1.51649
MPHOSPH6 M-phase phosphoprotein 6 -1.51112
IGFBP7 insulin-like growth factor binding protein 7 -1.51011
DTX4 deltex 4, E3 ubiquitin ligase -1.50939
CLIC4 chloride intracellular channel 4 -1.50878
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -1.50729
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 -1.50652
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.50645
TRIP12 thyroid hormone receptor interactor 12 -1.50339
RELN reelin -1.50182
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -1.49601
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -1.49468
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -1.49408
ADPGK ADP-dependent glucokinase -1.49211
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein -1.49197
ASL argininosuccinate lyase -1.49193
AIP aryl hydrocarbon receptor interacting protein -1.4839
BFAR bifunctional apoptosis regulator -1.48385
RAB11FIP5 RAB11 family interacting protein 5 (class I) -1.47976
IGSF1 immunoglobulin superfamily, member 1 -1.47973
PVT1 Pvt1 oncogene (non-protein coding) -1.4796
WDR82 WD repeat domain 82 -1.47944
TEX261 testis expressed 261 -1.47939
ATP9B ATPase, class II, type 9B -1.47815
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -1.47624
HHEX hematopoietically expressed homeobox -1.47161
GNL1 guanine nucleotide binding protein-like 1 -1.47005
AGBL2 ATP/GTP binding protein-like 2 -1.46898
PMPCA peptidase (mitochondrial processing) alpha -1.46461
TRAPPC4 trafficking protein particle complex 4 -1.46445
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -1.46355
TMEM30A transmembrane protein 30A -1.46063
TSPAN14 tetraspanin 14 -1.45907
ADORA2B adenosine A2b receptor -1.45632
STAT5B signal transducer and activator of transcription 5B -1.4551
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -1.4531
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -1.45305
SERP1 stress-associated endoplasmic reticulum protein 1 -1.45246
LRRC14 leucine rich repeat containing 14 -1.45055
ADGRL3 adhesion G protein-coupled receptor L3 -1.45004
AUP1 ancient ubiquitous protein 1 -1.44793
KLF3 Kruppel-like factor 3 (basic) -1.44655
ESRRA estrogen-related receptor alpha -1.44268
MDC1 mediator of DNA-damage checkpoint 1 -1.44162
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 -1.43952
DONSON downstream neighbor of SON -1.43543
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -1.43532
MUTYH mutY homolog -1.4353
CNTN1 contactin 1 -1.43418
WDR77 WD repeat domain 77 -1.43366
TM9SF1 transmembrane 9 superfamily member 1 -1.43271
OSR2 odd-skipped related transciption factor 2 -1.43055
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.43044
AP4S1 adaptor-related protein complex 4, sigma 1 subunit -1.42956
MED25 mediator complex subunit 25 -1.42864
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -1.42738
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -1.42667
THAP4 THAP domain containing 4 -1.42646
PARK2 parkin RBR E3 ubiquitin protein ligase -1.42257
NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 -1.42205
SCRG1 stimulator of chondrogenesis 1 -1.42205
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -1.41995
CALCOCO2 calcium binding and coiled-coil domain 2 -1.41829
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -1.41444
WDR26 WD repeat domain 26 -1.4136
CPQ carboxypeptidase Q -1.41105
ISOC1 isochorismatase domain containing 1 -1.41087
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -1.41079
FBXW11 F-box and WD repeat domain containing 11 -1.40994
IL13RA1 interleukin 13 receptor, alpha 1 -1.40927
TEX10 testis expressed 10 -1.40878
SP100 SP100 nuclear antigen -1.40855
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -1.40796
ASXL1 additional sex combs like transcriptional regulator 1 -1.40789