Pleural Effusion Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The presence of an excessive amount of fluid in the pleural cavity. (Human Phenotype Ontology, HP_0002202)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010996
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Genes

611 genes/proteins associated with the disease Pleural Effusion from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNF tumor necrosis factor 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.11541
IGF1 insulin-like growth factor 1 (somatomedin C) 1.92785
BAX BCL2-associated X protein 1.89121
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.88786
IL6 interleukin 6 1.87093
MPO myeloperoxidase 1.85151
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.81994
TAGLN transgelin 1.79961
GSTM1 glutathione S-transferase mu 1 1.7977
GSTP1 glutathione S-transferase pi 1 1.78129
IGFBP3 insulin-like growth factor binding protein 3 1.78071
SOD2 superoxide dismutase 2, mitochondrial 1.78013
BCL2 B-cell CLL/lymphoma 2 1.77609
DDIT3 DNA-damage-inducible transcript 3 1.75934
IL1B interleukin 1, beta 1.7568
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.7566
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.7542
IFNG interferon, gamma 1.754
CAT catalase 1.75241
IL4 interleukin 4 1.74501
TGFB1 transforming growth factor, beta 1 1.73292
CCL2 chemokine (C-C motif) ligand 2 1.72738
F3 coagulation factor III (thromboplastin, tissue factor) 1.72467
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.71627
ALDOA aldolase A, fructose-bisphosphate 1.71152
VEGFA vascular endothelial growth factor A 1.70553
JUN jun proto-oncogene 1.70512
BCL2L1 BCL2-like 1 1.70244
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.69617
IL10 interleukin 10 1.6947
ATF3 activating transcription factor 3 1.68889
IL1A interleukin 1, alpha 1.68846
S100A9 S100 calcium binding protein A9 1.67654
TP53 tumor protein p53 1.67547
HMOX1 heme oxygenase 1 1.67462
GPX1 glutathione peroxidase 1 1.67181
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.6649
NOS2 nitric oxide synthase 2, inducible 1.6621
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.65555
NQO1 NAD(P)H dehydrogenase, quinone 1 1.65045
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.6482
TEX261 testis expressed 261 1.64213
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.63406
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.63183
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.62268
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.62222
VCAM1 vascular cell adhesion molecule 1 1.61944
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.61759
RB1 retinoblastoma 1 1.61552
GCLC glutamate-cysteine ligase, catalytic subunit 1.60012
PDE4B phosphodiesterase 4B, cAMP-specific 1.59966
PRL prolactin 1.59826
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.59381
ICAM1 intercellular adhesion molecule 1 1.59264
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.58491
NFE2L2 nuclear factor, erythroid 2-like 2 1.58089
INHBA inhibin, beta A 1.57688
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.57498
POMC proopiomelanocortin 1.56459
ALB albumin 1.5641
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.55648
PPARG peroxisome proliferator-activated receptor gamma 1.555
EGFR epidermal growth factor receptor 1.55476
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.55451
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.55231
CXCL8 chemokine (C-X-C motif) ligand 8 1.54645
TIMP1 TIMP metallopeptidase inhibitor 1 1.54499
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.54281
GSR glutathione reductase 1.54111
G6PD glucose-6-phosphate dehydrogenase 1.53772
RGS4 regulator of G-protein signaling 4 1.53012
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.52718
NPPB natriuretic peptide B 1.52566
CCNG1 cyclin G1 1.52566
MCL1 myeloid cell leukemia 1 1.52464
CFLAR CASP8 and FADD-like apoptosis regulator 1.52036
RRM2 ribonucleotide reductase M2 1.51886
KRT8 keratin 8, type II 1.51708
CCND1 cyclin D1 1.51582
ODC1 ornithine decarboxylase 1 1.51531
DUSP1 dual specificity phosphatase 1 1.5143
GPX3 glutathione peroxidase 3 1.50903
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.4889
FAS Fas cell surface death receptor 1.48736
VLDLR very low density lipoprotein receptor 1.48093
SRGN serglycin 1.47966
MAPK1 mitogen-activated protein kinase 1 1.47634
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.47556
FABP4 fatty acid binding protein 4, adipocyte 1.47556
IL12B interleukin 12B 1.47374
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.47141
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.46727
MMP9 matrix metallopeptidase 9 1.46648
FOXO1 forkhead box O1 1.46568
FOS FBJ murine osteosarcoma viral oncogene homolog 1.46225
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.46093
PPARA peroxisome proliferator-activated receptor alpha 1.46041
PLAU plasminogen activator, urokinase 1.46015
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.4575
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.44954
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.44927
NOS3 nitric oxide synthase 3 (endothelial cell) 1.44899
MBP myelin basic protein 1.44708
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.44382
FKBP5 FK506 binding protein 5 1.44111
CTSL cathepsin L 1.43892
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.43782
PLTP phospholipid transfer protein 1.43755
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.437
HSPA8 heat shock 70kDa protein 8 1.42589
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.42401
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.41965
IL5 interleukin 5 1.41856
IL18 interleukin 18 1.41856
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.41829
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.41478
PRKCE protein kinase C, epsilon 1.41119
CLU clusterin 1.41008
FGF2 fibroblast growth factor 2 (basic) 1.40897
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.4076
PARP1 poly (ADP-ribose) polymerase 1 1.40568
THBS1 thrombospondin 1 1.40401
ANXA2 annexin A2 1.40401
COL1A1 collagen, type I, alpha 1 1.40288
SOD1 superoxide dismutase 1, soluble 1.40064
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.39952
NES nestin 1.39869
STAR steroidogenic acute regulatory protein 1.39366
PRDX1 peroxiredoxin 1 1.39366
MAPK3 mitogen-activated protein kinase 3 1.39198
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.38946
IGF2 insulin-like growth factor 2 1.38696
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.38641
TH tyrosine hydroxylase 1.38584
FASN fatty acid synthase 1.38584
HSPA1A heat shock 70kDa protein 1A 1.38469
PCNA proliferating cell nuclear antigen 1.38384
COL3A1 collagen, type III, alpha 1 1.38043
POR P450 (cytochrome) oxidoreductase 1.38015
FBXO32 F-box protein 32 1.37987
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.37987
LHB luteinizing hormone beta polypeptide 1.3793
IL1RN interleukin 1 receptor antagonist 1.37902
EGR1 early growth response 1 1.3759
RXRG retinoid X receptor, gamma 1.37217
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.37103
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.36961
CNR1 cannabinoid receptor 1 (brain) 1.36933
CRYAB crystallin, alpha B 1.36791
CCL3 chemokine (C-C motif) ligand 3 1.36735
KCTD12 potassium channel tetramerization domain containing 12 1.36735
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.36619
GDNF glial cell derived neurotrophic factor 1.36218
IL12A interleukin 12A 1.36161
GCLM glutamate-cysteine ligase, modifier subunit 1.35991
RRAS related RAS viral (r-ras) oncogene homolog 1.35849
PKP2 plakophilin 2 1.35849
ATF4 activating transcription factor 4 1.3556
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.35415
CPT1A carnitine palmitoyltransferase 1A (liver) 1.35271
JAK1 Janus kinase 1 1.34811
TIMP2 TIMP metallopeptidase inhibitor 2 1.34547
MMP3 matrix metallopeptidase 3 1.34401
ACO2 aconitase 2, mitochondrial 1.34343
AKR1C3 aldo-keto reductase family 1, member C3 1.34256
ASL argininosuccinate lyase 1.34169
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.3388
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.33405
MMP2 matrix metallopeptidase 2 1.33405
ERBB4 erb-b2 receptor tyrosine kinase 4 1.33346
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.33228
GFAP glial fibrillary acidic protein 1.32993
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.32993
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 1.32667
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.32577
KLF4 Kruppel-like factor 4 (gut) 1.32577
BHLHE40 basic helix-loop-helix family, member e40 1.32577
LIF leukemia inhibitory factor 1.32577
TYMS thymidylate synthetase 1.32428
LSP1 lymphocyte-specific protein 1 1.32192
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.32162
GSK3B glycogen synthase kinase 3 beta 1.31985
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.31837
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.31776
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.31716
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.31716
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.31626
CXCL2 chemokine (C-X-C motif) ligand 2 1.31416
SPP1 secreted phosphoprotein 1 1.31237
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.31089
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.30727
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.30696
FSHB follicle stimulating hormone, beta polypeptide 1.30056
MAP2K1 mitogen-activated protein kinase kinase 1 1.29936
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.29905
GNAS GNAS complex locus 1.29905
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.29812
GADD45A growth arrest and DNA-damage-inducible, alpha 1.29781
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.29533
CTGF connective tissue growth factor 1.2941
MMP1 matrix metallopeptidase 1 1.2941
CD36 CD36 molecule (thrombospondin receptor) 1.29041
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.28919
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.28919
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.28919
OSBPL8 oxysterol binding protein-like 8 1.28889
GDF15 growth differentiation factor 15 1.28796
LOX lysyl oxidase 1.28734
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.28672
SFRP2 secreted frizzled-related protein 2 1.28672
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.28518
PRNP prion protein 1.28518
TLR4 toll-like receptor 4 1.28425
CCNB1 cyclin B1 1.28303
GJA1 gap junction protein, alpha 1, 43kDa 1.2818
PPARD peroxisome proliferator-activated receptor delta 1.28149
VIM vimentin 1.27936
XDH xanthine dehydrogenase 1.27936
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.27782
FASLG Fas ligand (TNF superfamily, member 6) 1.2772
BACE1 beta-site APP-cleaving enzyme 1 1.2772
ACADVL acyl-CoA dehydrogenase, very long chain 1.27689
TEK TEK tyrosine kinase, endothelial 1.27409
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.27224
SREBF1 sterol regulatory element binding transcription factor 1 1.27224
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.2707
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 1.2707
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.26886
RFC3 replication factor C (activator 1) 3, 38kDa 1.26794
S100A8 S100 calcium binding protein A8 1.26732
PRKCB protein kinase C, beta 1.26732
TIMP3 TIMP metallopeptidase inhibitor 3 1.26732
ADIPOQ adiponectin, C1Q and collagen domain containing 1.26545
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.26545
ARRDC3 arrestin domain containing 3 1.26483
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.2639
APP amyloid beta (A4) precursor protein 1.26329
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.26267
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.25868
LPL lipoprotein lipase 1.25432
REL v-rel avian reticuloendotheliosis viral oncogene homolog 1.25307
HSPB1 heat shock 27kDa protein 1 1.25307
MAP2K2 mitogen-activated protein kinase kinase 2 1.25183
RAD17 RAD17 homolog (S. pombe) 1.25121
TXN thioredoxin 1.25028
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.25028
CXCL10 chemokine (C-X-C motif) ligand 10 1.24874
DUSP4 dual specificity phosphatase 4 1.2475
NDRG2 NDRG family member 2 1.2475
ANGPTL4 angiopoietin-like 4 1.24687
IRS1 insulin receptor substrate 1 1.24687
IL2 interleukin 2 1.24687
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.2456
SRXN1 sulfiredoxin 1 1.24528
CSF3 colony stimulating factor 3 (granulocyte) 1.24528
CKM creatine kinase, muscle 1.24496
CCNE1 cyclin E1 1.24465
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.24181
EDN1 endothelin 1 1.2415
TSPAN4 tetraspanin 4 1.23993
LBP lipopolysaccharide binding protein 1.2393
MAPK9 mitogen-activated protein kinase 9 1.2393
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.23868
EGF epidermal growth factor 1.23837
EDNRB endothelin receptor type B 1.23712
KITLG KIT ligand 1.23648
PIR pirin (iron-binding nuclear protein) 1.23648
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.23392
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.23392
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.23233
UBC ubiquitin C 1.22884
NUPR1 nuclear protein, transcriptional regulator, 1 1.22632
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.22599
MMP13 matrix metallopeptidase 13 1.22469
GRB7 growth factor receptor-bound protein 7 1.22436
WEE1 WEE1 G2 checkpoint kinase 1.22339
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.22339
UGCG UDP-glucose ceramide glucosyltransferase 1.22339
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.22177
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.22177
XBP1 X-box binding protein 1 1.22177
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.2208
MAPK14 mitogen-activated protein kinase 14 1.2208
TRIB3 tribbles pseudokinase 3 1.21855
PECAM1 platelet/endothelial cell adhesion molecule 1 1.21855
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.21599
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.21599
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.21599
CAPN2 calpain 2, (m/II) large subunit 1.2137
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.2137
MT1X metallothionein 1X 1.21337
EIF4E eukaryotic translation initiation factor 4E 1.21337
BDNF brain-derived neurotrophic factor 1.21076
CAV1 caveolin 1, caveolae protein, 22kDa 1.20978
FOSL2 FOS-like antigen 2 1.20848
PLG plasminogen 1.20848
DDIT4 DNA-damage-inducible transcript 4 1.20526
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.20361
GATA3 GATA binding protein 3 1.20361
THBD thrombomodulin 1.20361
IL6ST interleukin 6 signal transducer 1.199
NCOA2 nuclear receptor coactivator 2 1.19868
COL1A2 collagen, type I, alpha 2 1.19672
MAP2K6 mitogen-activated protein kinase kinase 6 1.19412
CP ceruloplasmin (ferroxidase) 1.19279
HSPA4 heat shock 70kDa protein 4 1.19213
BST2 bone marrow stromal cell antigen 2 1.1908
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.18981
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.18981
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.18948
LPAR2 lysophosphatidic acid receptor 2 1.18685
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.18326
ETFDH electron-transferring-flavoprotein dehydrogenase 1.18226
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.18226
TNC tenascin C 1.18093
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.18059
THRSP thyroid hormone responsive 1.1786
HSF1 heat shock transcription factor 1 1.1786
NPR1 natriuretic peptide receptor 1 1.17827
ADRB2 adrenoceptor beta 2, surface 1.17662
MT2A metallothionein 2A 1.17662
BIRC5 baculoviral IAP repeat containing 5 1.17629
KDR kinase insert domain receptor 1.1753
GBP1 guanylate binding protein 1, interferon-inducible 1.17431
VGF VGF nerve growth factor inducible 1.17399
CCL4 chemokine (C-C motif) ligand 4 1.17399
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.17034
LDLR low density lipoprotein receptor 1.17
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 1.17
ORM1 orosomucoid 1 1.16833
PLIN2 perilipin 2 1.16799
TSC22D3 TSC22 domain family, member 3 1.16799
SYK spleen tyrosine kinase 1.166
OCLN occludin 1.16401
GSTT1 glutathione S-transferase theta 1 1.16368
E2F3 E2F transcription factor 3 1.16236
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.16236
NET1 neuroepithelial cell transforming 1 1.16236
NOX4 NADPH oxidase 4 1.16203
DSC2 desmocollin 2 1.16203
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 1.16001
MSMO1 methylsterol monooxygenase 1 1.15967
NGF nerve growth factor (beta polypeptide) 1.15865
THRA thyroid hormone receptor, alpha 1.15593
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.15593
PLA1A phospholipase A1 member A 1.15492
CDKN2A cyclin-dependent kinase inhibitor 2A 1.15492
OTC ornithine carbamoyltransferase 1.15458
ELAVL1 ELAV like RNA binding protein 1 1.15458
CBR1 carbonyl reductase 1 1.15189
SERINC3 serine incorporator 3 1.15122
JUNB jun B proto-oncogene 1.15122
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.15055
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.14989
COL9A1 collagen, type IX, alpha 1 1.14816
HMGB1 high mobility group box 1 1.14816
F2R coagulation factor II (thrombin) receptor 1.14816
H2AFX H2A histone family, member X 1.14781
PLAT plasminogen activator, tissue 1.14781
PTEN phosphatase and tensin homolog 1.14781
TOP2A topoisomerase (DNA) II alpha 170kDa 1.14747
RBPMS RNA binding protein with multiple splicing 1.14713
BAD BCL2-associated agonist of cell death 1.14644
ALAS1 5'-aminolevulinate synthase 1 1.14575
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.14438
APOE apolipoprotein E 1.14404
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 1.1437
SPON1 spondin 1, extracellular matrix protein 1.14336
PALLD palladin, cytoskeletal associated protein 1.14336
KMT2A lysine (K)-specific methyltransferase 2A 1.13997
LAMC1 laminin, gamma 1 (formerly LAMB2) 1.13963
NPPA natriuretic peptide A 1.13929
CYCS cytochrome c, somatic 1.13895
ADORA3 adenosine A3 receptor 1.13655
AVP arginine vasopressin 1.13655
EPOR erythropoietin receptor 1.13621
PDLIM7 PDZ and LIM domain 7 (enigma) 1.13621
SPON2 spondin 2, extracellular matrix protein 1.13621
HRAS Harvey rat sarcoma viral oncogene homolog 1.13484
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.13484
EGR2 early growth response 2 1.13449
IRF1 interferon regulatory factor 1 1.13449
PRDX2 peroxiredoxin 2 1.13449
TFRC transferrin receptor 1.13449
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.13109
FMO2 flavin containing monooxygenase 2 (non-functional) 1.13007
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.12668
MDK midkine (neurite growth-promoting factor 2) 1.12668
LGALS3 lectin, galactoside-binding, soluble, 3 1.12564
MIR150 microRNA 150 1.12357
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 1.12323
PKNOX2 PBX/knotted 1 homeobox 2 1.12288
NOL6 nucleolar protein 6 (RNA-associated) 1.12288
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.12014
MT1G metallothionein 1G 1.1198
C10ORF10 chromosome 10 open reading frame 10 1.11673
TFF3 trefoil factor 3 (intestinal) 1.11673
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.11673
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.11639
GUCY1B3 guanylate cyclase 1, soluble, beta 3 1.11639
CRHBP corticotropin releasing hormone binding protein 1.11571
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.11501
REPIN1 replication initiator 1 1.11501
TAC1 tachykinin, precursor 1 1.11466
GSTA1 glutathione S-transferase alpha 1 1.1136
CALB1 calbindin 1, 28kDa 1.1136
GATA2 GATA binding protein 2 1.11325
MT1E metallothionein 1E 1.11325
ACTG2 actin, gamma 2, smooth muscle, enteric 1.11325
RAD51 RAD51 recombinase 1.11325
MCAM melanoma cell adhesion molecule 1.11046
RHOA ras homolog family member A 1.10838
EPHX2 epoxide hydrolase 2, cytoplasmic 1.10838
BBC3 BCL2 binding component 3 1.10838
RGS13 regulator of G-protein signaling 13 1.10803
C8ORF4 chromosome 8 open reading frame 4 1.10803
ELMOD3 ELMO/CED-12 domain containing 3 1.10803
ANGPT1 angiopoietin 1 1.10699
ARNT aryl hydrocarbon receptor nuclear translocator 1.10665
KRT18 keratin 18, type I 1.10665
ADM adrenomedullin 1.10665
AR androgen receptor 1.10596
CYBB cytochrome b-245, beta polypeptide 1.10493
POSTN periostin, osteoblast specific factor 1.10424
SFTPB surfactant protein B 1.10424
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.10388
HAS2 hyaluronan synthase 2 1.10388
CHUK conserved helix-loop-helix ubiquitous kinase 1.10353
TGFA transforming growth factor, alpha 1.10317
BID BH3 interacting domain death agonist 1.10175
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.10104
GAMT guanidinoacetate N-methyltransferase 1.10104
DUSP10 dual specificity phosphatase 10 1.10104
IL3 interleukin 3 1.10104
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.10069
GADD45B growth arrest and DNA-damage-inducible, beta 1.09998
FABP1 fatty acid binding protein 1, liver 1.09998
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.09857
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.09822
KEAP1 kelch-like ECH-associated protein 1 1.09822
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.09822
GH1 growth hormone 1 1.09681
ACSL1 acyl-CoA synthetase long-chain family member 1 1.09681
ALAS2 5'-aminolevulinate synthase 2 1.09506
CRH corticotropin releasing hormone 1.09506
MXD1 MAX dimerization protein 1 1.09506
GTPBP1 GTP binding protein 1 1.09436
CYR61 cysteine-rich, angiogenic inducer, 61 1.09366
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.09262
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.09226
MAPK10 mitogen-activated protein kinase 10 1.09226
PML promyelocytic leukemia 1.09226
APOD apolipoprotein D 1.09226
AK4 adenylate kinase 4 1.09226
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.0919
CCND3 cyclin D3 1.09011
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.0894
SOCS1 suppressor of cytokine signaling 1 1.0894
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.0894
S100A11 S100 calcium binding protein A11 1.08904
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.08868
HMHA1 histocompatibility (minor) HA-1 1.08762
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.08655
PFKP phosphofructokinase, platelet 1.08655
CDK2 cyclin-dependent kinase 2 1.08655
NPY neuropeptide Y 1.08407
DBP D site of albumin promoter (albumin D-box) binding protein 1.08372
ADIPOR2 adiponectin receptor 2 1.08372
FN1 fibronectin 1 1.08266
HSPA1B heat shock 70kDa protein 1B 1.08266
TGFB2 transforming growth factor, beta 2 1.08266
BRCA1 breast cancer 1, early onset 1.08231
HLA-DRA major histocompatibility complex, class II, DR alpha 1.08126
FHL1 four and a half LIM domains 1 1.08091
ECI1 enoyl-CoA delta isomerase 1 1.08091
BAK1 BCL2-antagonist/killer 1 1.08091
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.08091
MRPS12 mitochondrial ribosomal protein S12 1.08091
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.07947
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.07804
DPPA4 developmental pluripotency associated 4 1.07732
HSF2 heat shock transcription factor 2 1.07518
MXRA7 matrix-remodelling associated 7 1.07518
ELMO1 engulfment and cell motility 1 1.07482
SGK1 serum/glucocorticoid regulated kinase 1 1.0734
MEF2C myocyte enhancer factor 2C 1.07305
SDC1 syndecan 1 1.07305
AKAP12 A kinase (PRKA) anchor protein 12 1.07269
RORA RAR-related orphan receptor A 1.07269
ZEB1 zinc finger E-box binding homeobox 1 1.07269
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.07199
CAPN1 calpain 1, (mu/I) large subunit 1.07057
CXCR4 chemokine (C-X-C motif) receptor 4 1.07022
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.06917
CCND2 cyclin D2 1.06881
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 1.06881
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.06881
SOX13 SRY (sex determining region Y)-box 13 1.06881
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.06808
STAT5A signal transducer and activator of transcription 5A 1.06771
PER1 period circadian clock 1 1.06734
INS insulin 1.06734
CREB1 cAMP responsive element binding protein 1 1.06734
TYMP thymidine phosphorylase 1.06588
PRC1 protein regulator of cytokinesis 1 1.06515
LCN2 lipocalin 2 1.06442
CTSB cathepsin B 1.06442
SP1 Sp1 transcription factor 1.06297
BTG2 BTG family, member 2 1.06297
HEXB hexosaminidase B (beta polypeptide) 1.06297
SELL selectin L 1.06261
COL18A1 collagen, type XVIII, alpha 1 1.06225
C3 complement component 3 1.05757
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.05721
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.05721
TF transferrin 1.0561
CD44 CD44 molecule (Indian blood group) 1.05461
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.05461
EFNA1 ephrin-A1 1.05461
ESR1 estrogen receptor 1 1.05274
EPX eosinophil peroxidase 1.05126
CFB complement factor B 1.04941
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.04941
S100A10 S100 calcium binding protein A10 1.04941
CTSD cathepsin D 1.04868
LEP leptin 1.04868
SQSTM1 sequestosome 1 1.04721
WIPF1 WAS/WASL interacting protein family, member 1 1.04684
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.04465
MMP7 matrix metallopeptidase 7 1.04465
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.04465
HK2 hexokinase 2 1.04465
CXCL12 chemokine (C-X-C motif) ligand 12 1.04314
TAT tyrosine aminotransferase 1.04239
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.04201
RGS8 regulator of G-protein signaling 8 1.04126
HOXA5 homeobox A5 1.04088
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 1.04088
PRKCD protein kinase C, delta 1.04051
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.04014
ACAA2 acetyl-CoA acyltransferase 2 1.03976
ATF6 activating transcription factor 6 1.03976
PLCG1 phospholipase C, gamma 1 1.03976
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.03901
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.03789
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.03715
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.03715
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.03678
IL13 interleukin 13 1.03641
PBX2 pre-B-cell leukemia homeobox 2 1.03604
LZTFL1 leucine zipper transcription factor-like 1 1.03604
TNRC6A trinucleotide repeat containing 6A 1.03604
WNT5B wingless-type MMTV integration site family, member 5B 1.03604
LDHB lactate dehydrogenase B 1.03308
SOCS2 suppressor of cytokine signaling 2 1.03271
ACO1 aconitase 1, soluble 1.03271
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 1.03122
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 1.03084
SAT1 spermidine/spermine N1-acetyltransferase 1 1.03046
JARID2 jumonji, AT rich interactive domain 2 1.03046
MAPK4 mitogen-activated protein kinase 4 1.03046
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.02821
PER2 period circadian clock 2 1.02821
HADH hydroxyacyl-CoA dehydrogenase 1.02821
ALOX5 arachidonate 5-lipoxygenase 1.02708
MT1A metallothionein 1A 1.02708
VAV2 vav 2 guanine nucleotide exchange factor 1.02634
FOXJ1 forkhead box J1 1.02596
ETHE1 ethylmalonic encephalopathy 1 1.02596
PLD3 phospholipase D family, member 3 1.02559
LTF lactotransferrin 1.02447
MYD88 myeloid differentiation primary response 88 1.02373
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.02373
BAG3 BCL2-associated athanogene 3 1.02373
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.02373
RXRA retinoid X receptor, alpha 1.02336
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.02188
INPP1 inositol polyphosphate-1-phosphatase 1.02151
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.02114
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 1.02114
BIRC3 baculoviral IAP repeat containing 3 1.02077
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.02077
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.02077
FST follistatin 1.01928
PTGES prostaglandin E synthase 1.01928
MYOG myogenin (myogenic factor 4) 1.01739
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.01739
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.01701
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.01701
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.01701
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.01663
ANK1 ankyrin 1, erythrocytic 1.01663
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 1.01625
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.01587
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.01587
TPI1 triosephosphate isomerase 1 1.01512
WISP1 WNT1 inducible signaling pathway protein 1 1.01286
CPN1 carboxypeptidase N, polypeptide 1 1.01212
PRPH peripherin 1.01212
LIMCH1 LIM and calponin homology domains 1 1.01174
ARL4C ADP-ribosylation factor-like 4C 1.01174
COLEC12 collectin sub-family member 12 1.01174
KLF13 Kruppel-like factor 13 1.01137
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.01137
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.01099
CCNG2 cyclin G2 1.01099
CXCL5 chemokine (C-X-C motif) ligand 5 1.01099
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.01062
CDKN3 cyclin-dependent kinase inhibitor 3 1.01062
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.01062