Personality Disorders Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

41 genes associated with the Personality Disorders phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AFG3L2 AFG3-like AAA ATPase 2
AR androgen receptor
BDNF brain-derived neurotrophic factor
CHRM2 cholinergic receptor, muscarinic 2
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
GCH1 GTP cyclohydrolase 1
GSK3B glycogen synthase kinase 3 beta
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTT huntingtin
KCNIP4 Kv channel interacting protein 4
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
MAOA monoamine oxidase A
MAT1A methionine adenosyltransferase I, alpha
MAT2A methionine adenosyltransferase II, alpha
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NOS1 nitric oxide synthase 1 (neuronal)
PLXNA2 plexin A2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SYNJ1 synaptojanin 1
SYNJ2 synaptojanin 2
TH tyrosine hydroxylase
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2