Peritonitis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A gastrointestinal system disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, fluid in the abdomen, nausea, vomiting and low urine output. (Human Disease Ontology, DOID_8283)
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Genes

11 genes associated with the Peritonitis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
CCL2 chemokine (C-C motif) ligand 2
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
LEP leptin
LEPR leptin receptor
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
NOD2 nucleotide-binding oligomerization domain containing 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TLR2 toll-like receptor 2