Parkinson Disease Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions. (Human Disease Ontology, DOID_14330)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D010300
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Genes

517 genes/proteins associated with the disease Parkinson Disease from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
PARK7 parkinson protein 7 2.88009
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.88009
MAPT microtubule-associated protein tau 2.88009
INSR insulin receptor 2.88009
PARK16 Parkinson disease 16 (susceptibility) 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.88009
MAOA monoamine oxidase A 2.88009
MAOB monoamine oxidase B 2.88009
FGB fibrinogen beta chain 2.88009
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.88009
NGF nerve growth factor (beta polypeptide) 2.88009
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.88009
GAK cyclin G associated kinase 2.88009
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 2.88009
POR P450 (cytochrome) oxidoreductase 2.88009
CP ceruloplasmin (ferroxidase) 2.88009
HMOX1 heme oxygenase 1 2.88009
IL6 interleukin 6 2.88009
RPL14 ribosomal protein L14 2.88009
EDN1 endothelin 1 2.88009
MAG myelin associated glycoprotein 2.88009
PINK1 PTEN induced putative kinase 1 2.88009
DRD1 dopamine receptor D1 2.88009
DRD2 dopamine receptor D2 2.88009
FBP1 fructose-1,6-bisphosphatase 1 2.88009
RPL6 ribosomal protein L6 2.88009
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 2.88009
ATP13A2 ATPase type 13A2 2.88009
SOD1 superoxide dismutase 1, soluble 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
HSPA1A heat shock 70kDa protein 1A 2.88009
HLA-DRA major histocompatibility complex, class II, DR alpha 2.88009
PARK2 parkin RBR E3 ubiquitin protein ligase 2.88009
LRRK2 leucine-rich repeat kinase 2 2.88009
TALDO1 transaldolase 1 2.88009
TNF tumor necrosis factor 2.88009
GSTA4 glutathione S-transferase alpha 4 2.88009
IGF1R insulin-like growth factor 1 receptor 2.88009
CHP1 calcineurin-like EF-hand protein 1 2.88009
HFE hemochromatosis 2.88009
BDNF brain-derived neurotrophic factor 2.88009
GSTP1 glutathione S-transferase pi 1 2.88009
HSPA9 heat shock 70kDa protein 9 (mortalin) 2.88009
UPP1 uridine phosphorylase 1 2.88009
MAP3K5 mitogen-activated protein kinase kinase kinase 5 2.88009
NQO1 NAD(P)H dehydrogenase, quinone 1 2.88009
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 2.88009
GBA glucosidase, beta, acid 2.88009
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2.88009
DDIT4 DNA-damage-inducible transcript 4 2.88009
RPL23A ribosomal protein L23a 2.88009
INS insulin 2.88009
RPS8 ribosomal protein S8 2.88009
BST1 bone marrow stromal cell antigen 1 2.88009
AIF1 allograft inflammatory factor 1 2.88009
IGF2 insulin-like growth factor 2 2.88009
SLC30A10 solute carrier family 30, member 10 2.88009
GSTM1 glutathione S-transferase mu 1 2.88009
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.88009
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.88009
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 2.88009
GPX1 glutathione peroxidase 1 2.88009
GDNF glial cell derived neurotrophic factor 2.88009
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.88009
GFAP glial fibrillary acidic protein 2.88009
IGF2R insulin-like growth factor 2 receptor 2.88009
CAT catalase 2.36496
BAX BCL2-associated X protein 2.34229
TH tyrosine hydroxylase 2.31809
NOS2 nitric oxide synthase 2, inducible 2.24697
PRL prolactin 2.2458
EGR1 early growth response 1 2.22565
MAPK3 mitogen-activated protein kinase 3 2.22152
BCL2 B-cell CLL/lymphoma 2 2.19544
MAPK1 mitogen-activated protein kinase 1 2.18847
JUN jun proto-oncogene 2.18428
FOS FBJ murine osteosarcoma viral oncogene homolog 2.1753
NFE2L2 nuclear factor, erythroid 2-like 2 2.16225
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.15537
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.11211
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.09649
IFNG interferon, gamma 2.07684
COMT catechol-O-methyltransferase 2.07009
DRD3 dopamine receptor D3 2.05808
IL1B interleukin 1, beta 2.05645
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.04767
ALB albumin 2.03807
TP53 tumor protein p53 2.03663
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.03573
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.02698
FAS Fas cell surface death receptor 2.00647
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.0044
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.00426
CREB1 cAMP responsive element binding protein 1 1.97884
GSK3B glycogen synthase kinase 3 beta 1.95691
ACHE acetylcholinesterase (Yt blood group) 1.9428
GSR glutathione reductase 1.93398
VEGFA vascular endothelial growth factor A 1.89359
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.88622
PRKCD protein kinase C, delta 1.88622
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.85747
GSTT1 glutathione S-transferase theta 1 1.84429
CCND1 cyclin D1 1.84019
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.83895
MAPK8 mitogen-activated protein kinase 8 1.83272
CYCS cytochrome c, somatic 1.8313
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.81224
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.80567
TGFB1 transforming growth factor, beta 1 1.79579
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.78606
IGF1 insulin-like growth factor 1 (somatomedin C) 1.78052
IL10 interleukin 10 1.77355
DDIT3 DNA-damage-inducible transcript 3 1.77024
APP amyloid beta (A4) precursor protein 1.76771
PPARG peroxisome proliferator-activated receptor gamma 1.75281
CCL2 chemokine (C-C motif) ligand 2 1.74361
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.74361
ADORA2A adenosine A2a receptor 1.73818
BCL2L1 BCL2-like 1 1.7319
LEP leptin 1.72968
DUSP1 dual specificity phosphatase 1 1.71871
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.70574
TAC1 tachykinin, precursor 1 1.70491
GSTA1 glutathione S-transferase alpha 1 1.70306
CD36 CD36 molecule (thrombospondin receptor) 1.69211
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.6906
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.66857
MMP9 matrix metallopeptidase 9 1.66253
ESR1 estrogen receptor 1 1.65292
PENK proenkephalin 1.65023
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.64708
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.63473
NOS3 nitric oxide synthase 3 (endothelial cell) 1.6296
JUNB jun B proto-oncogene 1.62222
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.62129
CCL5 chemokine (C-C motif) ligand 5 1.62083
IL2 interleukin 2 1.61897
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.61897
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.61667
CCNB2 cyclin B2 1.61342
ERN1 endoplasmic reticulum to nucleus signaling 1 1.61201
MAPK9 mitogen-activated protein kinase 9 1.61178
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.60921
F2 coagulation factor II (thrombin) 1.60151
FASLG Fas ligand (TNF superfamily, member 6) 1.5992
ACO2 aconitase 2, mitochondrial 1.59755
NOS1 nitric oxide synthase 1 (neuronal) 1.59497
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.59288
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.58865
FN1 fibronectin 1 1.58351
ODC1 ornithine decarboxylase 1 1.579
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.57594
GCLC glutamate-cysteine ligase, catalytic subunit 1.57474
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.57329
CTSB cathepsin B 1.57186
GADD45A growth arrest and DNA-damage-inducible, alpha 1.56755
FASN fatty acid synthase 1.56459
MMP2 matrix metallopeptidase 2 1.56312
LPL lipoprotein lipase 1.56263
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.56092
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.55896
MAP2K1 mitogen-activated protein kinase kinase 1 1.55772
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.55157
POMC proopiomelanocortin 1.54986
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.54451
CCNB1 cyclin B1 1.54354
COL1A1 collagen, type I, alpha 1 1.54062
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.53844
MPO myeloperoxidase 1.53506
GJA1 gap junction protein, alpha 1, 43kDa 1.53036
CASP12 caspase 12 (gene/pseudogene) 1.52938
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.52743
NPY neuropeptide Y 1.52011
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.51632
SREBF1 sterol regulatory element binding transcription factor 1 1.51531
AR androgen receptor 1.50953
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.50599
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.50423
NUPR1 nuclear protein, transcriptional regulator, 1 1.50273
XBP1 X-box binding protein 1 1.49558
E2F1 E2F transcription factor 1 1.49304
PRKCA protein kinase C, alpha 1.49019
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 1.4889
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.48556
RGS2 regulator of G-protein signaling 2 1.48556
HSPB1 heat shock 27kDa protein 1 1.48428
TIMP3 TIMP metallopeptidase inhibitor 3 1.47991
DRD4 dopamine receptor D4 1.47838
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.47838
GMFB glia maturation factor, beta 1.46832
TIMP2 TIMP metallopeptidase inhibitor 2 1.46754
BID BH3 interacting domain death agonist 1.46515
PRDX6 peroxiredoxin 6 1.46225
G6PD glucose-6-phosphate dehydrogenase 1.4583
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.45803
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.4559
GH1 growth hormone 1 1.45326
PPARA peroxisome proliferator-activated receptor alpha 1.44899
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.44845
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.44708
MBP myelin basic protein 1.44626
PARP1 poly (ADP-ribose) polymerase 1 1.43864
PCNA proliferating cell nuclear antigen 1.43809
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.437
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.4351
CTSL cathepsin L 1.43374
ACO1 aconitase 1, soluble 1.4332
ATF3 activating transcription factor 3 1.43266
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.43021
EGFR epidermal growth factor receptor 1.42913
RTN4 reticulon 4 1.41965
SIRT1 sirtuin 1 1.41884
PDYN prodynorphin 1.41856
NCF1 neutrophil cytosolic factor 1 1.41721
PRNP prion protein 1.41586
JUND jun D proto-oncogene 1.41008
PDE5A phosphodiesterase 5A, cGMP-specific 1.40176
CXCL8 chemokine (C-X-C motif) ligand 8 1.4012
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.3931
ICAM1 intercellular adhesion molecule 1 1.3917
HSPA8 heat shock 70kDa protein 8 1.3878
PKM pyruvate kinase, muscle 1.38752
NEFH neurofilament, heavy polypeptide 1.38384
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.38242
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.38043
BBC3 BCL2 binding component 3 1.37902
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.37789
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 1.37761
PON1 paraoxonase 1 1.3759
BAD BCL2-associated agonist of cell death 1.37389
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.37217
SQSTM1 sequestosome 1 1.37217
CXCL2 chemokine (C-X-C motif) ligand 2 1.37103
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.36791
SPP1 secreted phosphoprotein 1 1.36791
UBC ubiquitin C 1.36791
FTH1 ferritin, heavy polypeptide 1 1.36562
GCLM glutamate-cysteine ligase, modifier subunit 1.36533
NAMPT nicotinamide phosphoribosyltransferase 1.36418
CRH corticotropin releasing hormone 1.35763
BCHE butyrylcholinesterase 1.35647
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.35618
RRM2 ribonucleotide reductase M2 1.35502
TFRC transferrin receptor 1.35444
HRAS Harvey rat sarcoma viral oncogene homolog 1.35444
ZFP36 ZFP36 ring finger protein 1.35444
MCL1 myeloid cell leukemia 1 1.35271
MAPK14 mitogen-activated protein kinase 14 1.35041
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.34518
EN1 engrailed homeobox 1 1.34518
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.34227
GRM5 glutamate receptor, metabotropic 5 1.34169
TGFB2 transforming growth factor, beta 2 1.33701
GPNMB glycoprotein (transmembrane) nmb 1.33672
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.33672
IRS2 insulin receptor substrate 2 1.32935
BIRC3 baculoviral IAP repeat containing 3 1.32846
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.32846
IL1R1 interleukin 1 receptor, type I 1.32696
ADORA1 adenosine A1 receptor 1.32399
TACC3 transforming, acidic coiled-coil containing protein 3 1.32221
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.32192
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.32103
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.31566
ENO1 enolase 1, (alpha) 1.31476
LHB luteinizing hormone beta polypeptide 1.31208
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.30758
GSTM3 glutathione S-transferase mu 3 (brain) 1.30512
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.30329
ATF4 activating transcription factor 4 1.30269
CALR calreticulin 1.30056
ATM ATM serine/threonine kinase 1.29781
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 1.29719
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.29471
CDKN3 cyclin-dependent kinase inhibitor 3 1.29317
PRKCE protein kinase C, epsilon 1.29194
APLP2 amyloid beta (A4) precursor-like protein 2 1.29133
CIRBP cold inducible RNA binding protein 1.29041
GSTA2 glutathione S-transferase alpha 2 1.28734
APOA1 apolipoprotein A-I 1.28734
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.28641
ALPP alkaline phosphatase, placental 1.28395
CDC20 cell division cycle 20 1.28364
S100A4 S100 calcium binding protein A4 1.28303
APOE apolipoprotein E 1.28119
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.27966
PDE4B phosphodiesterase 4B, cAMP-specific 1.27966
BECN1 beclin 1, autophagy related 1.27626
BIRC5 baculoviral IAP repeat containing 5 1.27595
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.2744
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.27316
FGF2 fibroblast growth factor 2 (basic) 1.27162
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.27009
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.26576
PRDX1 peroxiredoxin 1 1.26452
IL1A interleukin 1, alpha 1.26359
FTL ferritin, light polypeptide 1.26329
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.25682
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.25369
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.25338
PSEN1 presenilin 1 1.25307
ELK1 ELK1, member of ETS oncogene family 1.25307
GRM1 glutamate receptor, metabotropic 1 1.25276
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.24905
MT2A metallothionein 2A 1.24181
GPX3 glutathione peroxidase 3 1.2415
NGFR nerve growth factor receptor 1.24118
PRLR prolactin receptor 1.24118
ACSL5 acyl-CoA synthetase long-chain family member 5 1.23743
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.2352
CDK1 cyclin-dependent kinase 1 1.23488
VCAM1 vascular cell adhesion molecule 1 1.23296
PGF placental growth factor 1.22758
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.22242
PRDX2 peroxiredoxin 2 1.22016
CXCR4 chemokine (C-X-C motif) receptor 4 1.21919
TJP1 tight junction protein 1 1.21727
TRIB3 tribbles pseudokinase 3 1.21206
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.21141
MKI67 marker of proliferation Ki-67 1.21043
IGFBP1 insulin-like growth factor binding protein 1 1.20946
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.20751
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.20751
CDC42 cell division cycle 42 1.20751
NCF2 neutrophil cytosolic factor 2 1.20751
SP1 Sp1 transcription factor 1.20719
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.20394
LTF lactotransferrin 1.20394
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.20262
ACTB actin, beta 1.20229
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.20064
HSPA4 heat shock 70kDa protein 4 1.20031
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 1.20031
TF transferrin 1.19542
TXN2 thioredoxin 2 1.19445
HSPH1 heat shock 105kDa/110kDa protein 1 1.19412
FGF1 fibroblast growth factor 1 (acidic) 1.19412
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.19345
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.19047
FADD Fas (TNFRSF6)-associated via death domain 1.18981
TLR4 toll-like receptor 4 1.18882
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.18849
PNOC prepronociceptin 1.18685
KIF20A kinesin family member 20A 1.18652
S100A8 S100 calcium binding protein A8 1.18587
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.18293
CXCL5 chemokine (C-X-C motif) ligand 5 1.18293
XDH xanthine dehydrogenase 1.18093
BIN1 bridging integrator 1 1.18059
GPX2 glutathione peroxidase 2 1.18026
APAF1 apoptotic peptidase activating factor 1 1.18026
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.17959
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.17926
MDM4 MDM4, p53 regulator 1.17464
S100A6 S100 calcium binding protein A6 1.173
SDC2 syndecan 2 1.17235
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.16967
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.16567
GADD45B growth arrest and DNA-damage-inducible, beta 1.16434
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.16401
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.1617
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.1617
ATF2 activating transcription factor 2 1.16001
CCNA1 cyclin A1 1.15967
CAPN1 calpain 1, (mu/I) large subunit 1.15967
TXN thioredoxin 1.15899
GPC1 glypican 1 1.15763
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 1.1556
ANGPTL4 angiopoietin-like 4 1.15391
ARG2 arginase 2 1.15357
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.15357
FOXM1 forkhead box M1 1.15156
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.15122
MT1A metallothionein 1A 1.14885
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.14713
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.1461
MGST1 microsomal glutathione S-transferase 1 1.1461
AURKA aurora kinase A 1.14404
RB1 retinoblastoma 1 1.14166
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.1403
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.13862
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.13758
AHR aryl hydrocarbon receptor 1.13381
BAK1 BCL2-antagonist/killer 1 1.13347
GCH1 GTP cyclohydrolase 1 1.13177
CXCL10 chemokine (C-X-C motif) ligand 10 1.13143
FBXO32 F-box protein 32 1.13143
ALPL alkaline phosphatase, liver/bone/kidney 1.12872
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.12771
GSTM2 glutathione S-transferase mu 2 (muscle) 1.12771
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.12634
FKBP5 FK506 binding protein 5 1.12564
PDIA3 protein disulfide isomerase family A, member 3 1.12564
ALPI alkaline phosphatase, intestinal 1.12564
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 1.12391
ARC activity-regulated cytoskeleton-associated protein 1.12391
GSTA3 glutathione S-transferase alpha 3 1.12357
DAD1 defender against cell death 1 1.12117
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.12014
ALAD aminolevulinate dehydratase 1.1198
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.11911
FSHB follicle stimulating hormone, beta polypeptide 1.11775
CCND2 cyclin D2 1.11431
CCL3 chemokine (C-C motif) ligand 3 1.1122
IL12A interleukin 12A 1.11186
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.11081
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.11081
CDC25A cell division cycle 25A 1.10907
MMP1 matrix metallopeptidase 1 1.10769
CTGF connective tissue growth factor 1.10769
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 1.10699
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.10527
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.10493
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.09998
TXNRD1 thioredoxin reductase 1 1.09892
CPT1A carnitine palmitoyltransferase 1A (liver) 1.09786
IL5 interleukin 5 1.09786
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.09716
RPS6 ribosomal protein S6 1.09646
CAV1 caveolin 1, caveolae protein, 22kDa 1.09541
CDK2 cyclin-dependent kinase 2 1.09366
SCARB1 scavenger receptor class B, member 1 1.09332
CD14 CD14 molecule 1.09332
SIRT2 sirtuin 2 1.09332
IL12B interleukin 12B 1.08868
MT3 metallothionein 3 1.08726
CD38 CD38 molecule 1.08726
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.08726
ACADL acyl-CoA dehydrogenase, long chain 1.08655
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 1.08655
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 1.08655
VIM vimentin 1.08442
CLU clusterin 1.08442
MMP3 matrix metallopeptidase 3 1.08407
GAP43 growth associated protein 43 1.08372
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.08372
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.08266
FST follistatin 1.08055
RET ret proto-oncogene 1.08055
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 1.07875
CA2 carbonic anhydrase II 1.07732
STMN1 stathmin 1 1.07732
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.07732
TRIP13 thyroid hormone receptor interactor 13 1.07732
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.07518
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.07376
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.07022
DHCR24 24-dehydrocholesterol reductase 1.07022
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.06771
MAPK12 mitogen-activated protein kinase 12 1.06771
ADM adrenomedullin 1.06661
FGF9 fibroblast growth factor 9 1.06406
CDCA8 cell division cycle associated 8 1.06406
ACLY ATP citrate lyase 1.0637
CYBB cytochrome b-245, beta polypeptide 1.0637
HSF1 heat shock transcription factor 1 1.0637
ADIPOQ adiponectin, C1Q and collagen domain containing 1.06225
CYC1 cytochrome c-1 1.06152
HEPH hephaestin 1.06152
DIABLO diablo, IAP-binding mitochondrial protein 1.06008
KLHL24 kelch-like family member 24 1.05972
NFIB nuclear factor I/B 1.05972
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.05972
ACACA acetyl-CoA carboxylase alpha 1.05864
APOB apolipoprotein B 1.05864
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.05828
GSTA5 glutathione S-transferase alpha 5 1.05685
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.05685
BIRC2 baculoviral IAP repeat containing 2 1.05349
TTK TTK protein kinase 1.05126
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.05089
BTG1 B-cell translocation gene 1, anti-proliferative 1.05052
PARM1 prostate androgen-regulated mucin-like protein 1 1.05015
PRKCH protein kinase C, eta 1.04941
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.04904
ALDOA aldolase A, fructose-bisphosphate 1.04389
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.04352
SRXN1 sulfiredoxin 1 1.04314
IGFBP3 insulin-like growth factor binding protein 3 1.04276
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 1.04276
NEK2 NIMA-related kinase 2 1.04276
ADRB2 adrenoceptor beta 2, surface 1.04276
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.04126
ANXA1 annexin A1 1.04051
CHRM2 cholinergic receptor, muscarinic 2 1.04051
B2M beta-2-microglobulin 1.03752
IL4 interleukin 4 1.03641
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.03641
UBE2C ubiquitin-conjugating enzyme E2C 1.03419
RACGAP1 Rac GTPase activating protein 1 1.03419
LDLR low density lipoprotein receptor 1.03235
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.03122
E2F8 E2F transcription factor 8 1.03009
WT1 Wilms tumor 1 1.03009
RAD51AP1 RAD51 associated protein 1 1.03009
THRA thyroid hormone receptor, alpha 1.02821
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.02821
HSPA1B heat shock 70kDa protein 1B 1.02783
GPX4 glutathione peroxidase 4 1.02485
CHRM1 cholinergic receptor, muscarinic 1 1.02485
APLP1 amyloid beta (A4) precursor-like protein 1 1.02373
STRBP spermatid perinuclear RNA binding protein 1.02373
ACP5 acid phosphatase 5, tartrate resistant 1.02225
EIF5 eukaryotic translation initiation factor 5 1.02225
FKBP4 FK506 binding protein 4, 59kDa 1.02225
ANKRD37 ankyrin repeat domain 37 1.02077
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.0189
PBK PDZ binding kinase 1.01814
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.01587
COX5B cytochrome c oxidase subunit Vb 1.01549
LITAF lipopolysaccharide-induced TNF factor 1.01437
SGK1 serum/glucocorticoid regulated kinase 1 1.01324
TK1 thymidine kinase 1, soluble 1.01286
CCNE2 cyclin E2 1.01286
EIF2A eukaryotic translation initiation factor 2A, 65kDa 1.01062
EFNA1 ephrin-A1 1.01062
SDC4 syndecan 4 1.01062