Paratyphoid Fever Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A primary bacterial infectious disease that results_in infection located_in intestine, has_material_basis_in Salmonella enterica subsp enterica serovar Paratyphi A, B or C, which are transmitted_by ingestion of contaminated food. The infection has_symptom fever, has_symptom headache, has_symptom abdominal pain, has_symptom malaise, has_symptom anorexia, has_symptom constipation, has_symptom rosy spots on the central body, has_symptom non productive cough (in early stage of illness), has_symptom bradycardia, and has_symptom hepatosplenomegaly. (Human Disease Ontology, DOID_3055)
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Genes

11 genes associated with the Paratyphoid Fever phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
CASP1 caspase 1, apoptosis-related cysteine peptidase
CRP C-reactive protein, pentraxin-related
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
PARK2 parkin RBR E3 ubiquitin protein ligase
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A